Klaus-Dieter Schlüter Institute of Physiology Justus Liebig University Giessen Biography Publications Institution JoVE Articles Klaus-Dieter Schlüter has not added a biography. If you are Klaus-Dieter Schlüter and would like to personalize this page please email our Author Liaison for assistance. Publications Oxidized Low-density Lipoprotein (oxLDL) Affects Load-free Cell Shortening of Cardiomyocytes in a Proprotein Convertase Subtilisin/kexin 9 (PCSK9)-dependent Way Basic Research in Cardiology. Sep, 2017 | Pubmed ID: 28913715 Effects of 6-months' Exercise on Cardiac Function, Structure and Metabolism in Female Hypertensive Rats-The Decisive Role of Lysyl Oxidase and Collagen III Frontiers in Physiology. 2017 | Pubmed ID: 28824452 Physiological and Therapeutic Regulation of PCSK9 Activity in Cardiovascular Disease Basic Research in Cardiology. May, 2017 | Pubmed ID: 28439730 The Gap Junction Modifier ZP1609 Decreases Cardiomyocyte Hypercontracture Following Ischaemia/reperfusion Independent from Mitochondrial Connexin 43 British Journal of Pharmacology. Jul, 2017 | Pubmed ID: 28369703 Mitochondrial Cx43 Hemichannels Contribute to Mitochondrial Calcium Entry and Cell Death in the Heart Basic Research in Cardiology. May, 2017 | Pubmed ID: 28364353 PCSK9 Targets Important for Lipid Metabolism Clinical Research in Cardiology Supplements. Mar, 2017 | Pubmed ID: 28176216 Effect of Ticagrelor on Endothelial Calcium Signalling and Barrier Function Thrombosis and Haemostasis. Jan, 2017 | Pubmed ID: 27904901 The Role of Calcium-Sensing Receptors in Endothelin-1-Dependent Effects on Adult Rat Ventricular Cardiomyocytes: Possible Contribution to Adaptive Myocardial Hypertrophy Journal of Cellular Physiology. Sep, 2017 | Pubmed ID: 27662515 Effect of Nitric Oxide Deficiency on the Pulmonary PTHrP System Journal of Cellular and Molecular Medicine. Jan, 2017 | Pubmed ID: 27581501 The Effects of Swiprosin-1 on the Formation of Pseudopodia-Like Structures and β-Adrenoceptor Coupling in Cultured Adult Rat Ventricular Cardiomyocytes PloS One. 2016 | Pubmed ID: 27992454 Effect of High Fat Diet on Pulmonary Expression of Parathyroid Hormone-related Protein and Its Downstream Targets Heliyon. Oct, 2016 | Pubmed ID: 27830194 Diastolic Dysfunction in Prediabetic Male Rats: Role of Mitochondrial Oxidative Stress American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2016 | Pubmed ID: 27521417 Specific Mechanisms Underlying Right Heart Failure: The Missing Upregulation of Superoxide Dismutase-2 and Its Decisive Role in Antioxidative Defense Antioxidants & Redox Signaling. Nov, 2015 | Pubmed ID: 25978844 Pressure Overload, Sympathetic Drive, and Inflammation: is Ghrelin the Link? Hypertension (Dallas, Tex. : 1979). Jun, 2015 | Pubmed ID: 25870192 Arginase Induction and Activation During Ischemia and Reperfusion and Functional Consequences for the Heart Frontiers in Physiology. 2015 | Pubmed ID: 25814956 Molecular and Cellular Function of the Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Basic Research in Cardiology. Mar, 2015 | Pubmed ID: 25600226 Mechanism and Consequences of the Shift in Cardiac Arginine Metabolism Following Ischaemia and Reperfusion in Rats Thrombosis and Haemostasis. Mar, 2015 | Pubmed ID: 25502809 Mechanisms by Which Calcium Receptor Stimulation Modifies Electromechanical Coupling in Isolated Ventricular Cardiomyocytes Pflugers Archiv : European Journal of Physiology. Feb, 2015 | Pubmed ID: 24687204 Interleukin-6 Contributes to the Paracrine Effects of Cardiospheres Cultured from Human, Murine and Rat Hearts Journal of Cellular Physiology. Nov, 2014 | Pubmed ID: 24623002 Intrinsic Vascular Dopamine - a Key Modulator of Hypoxia-induced Vasodilatation in Splanchnic Vessels The Journal of Physiology. Apr, 2014 | Pubmed ID: 24535440 Renin and the IGFII/M6P Receptor System in Cardiac Biology TheScientificWorldJournal. 2013 | Pubmed ID: 24288471 Inhibition of AP-1 Signaling by JDP2 Overexpression Protects Cardiomyocytes Against Hypertrophy and Apoptosis Induction Cardiovascular Research. Jul, 2013 | Pubmed ID: 23612584 Reply from Klaus-Dieter Schluter and Rolf Schreckenberg The Journal of Physiology. Apr, 2013 | Pubmed ID: 23588505 Mechanisms Involved in Postconditioning Protection of Cardiomyocytes Against Acute Reperfusion Injury Journal of Molecular and Cellular Cardiology. May, 2013 | Pubmed ID: 23328483 Hypoxia-reoxygenation-induced Endothelial Barrier Failure: Role of RhoA, Rac1 and Myosin Light Chain Kinase The Journal of Physiology. Jan, 2013 | Pubmed ID: 23090948 Adverse Cardiac Remodelling in Spontaneously Hypertensive Rats: Acceleration by High Aerobic Exercise Intensity The Journal of Physiology. Nov, 2012 | Pubmed ID: 22930266 Effects of Nicotine on PTHrP and PTHrP Receptor Expression in Rat Coronary Endothelial Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2012 | Pubmed ID: 22508055 Effects of Cerivastatin on Adrenergic Pathways, Hypertrophic Growth and TGFbeta Expression in Adult Ventricular Cardiomyocytes European Journal of Cell Biology. May, 2012 | Pubmed ID: 22365145 Transforming Growth Factor β₁ Oppositely Regulates the Hypertrophic and Contractile Response to β-adrenergic Stimulation in the Heart PloS One. 2011 | Pubmed ID: 22125598 Rat Intermedin1-47 Does Not Improve Functional Recovery in Postischemic Hearts Naunyn-Schmiedeberg's Archives of Pharmacology. Dec, 2011 | Pubmed ID: 21881857 TGFβ Receptor Activation Enhances Cardiac Apoptosis Via SMAD Activation and Concomitant NO Release Journal of Cellular Physiology. Oct, 2011 | Pubmed ID: 21792926 Conditional Transgenic Expression of Fibroblast Growth Factor 9 in the Adult Mouse Heart Reduces Heart Failure Mortality After Myocardial Infarction Circulation. Feb, 2011 | Pubmed ID: 21262993 Interplay Between Ca2+ Cycling and Mitochondrial Permeability Transition Pores Promotes Reperfusion-induced Injury of Cardiac Myocytes Journal of Cellular and Molecular Medicine. Nov, 2011 | Pubmed ID: 21199327 Controlling Cardiomyocyte Length: the Role of Renin and PPAR-{gamma} Cardiovascular Research. Feb, 2011 | Pubmed ID: 20884641 Interaction Between Exercise and Hypertension in Spontaneously Hypertensive Rats: a Meta-analysis of Experimental Studies Hypertension Research : Official Journal of the Japanese Society of Hypertension. Nov, 2010 | Pubmed ID: 20720553 TGF-beta1 Improves Cardiac Performance Via Up-regulation of Laminin Receptor 37/67 in Adult Ventricular Cardiomyocytes Basic Research in Cardiology. Sep, 2010 | Pubmed ID: 20556404 New Insights into Paracrine Mechanisms of Human Cardiac Progenitor Cells European Journal of Heart Failure. Jul, 2010 | Pubmed ID: 20406797 Aldosterone Improves Contractile Function of Adult Rat Ventricular Cardiomyocytes in a Non-acute Way: Potential Relationship to the Calcium Paradox of Aldosteronism Basic Research in Cardiology. Mar, 2010 | Pubmed ID: 19763404 Parathyroid Hormone-related Protein (PTHrP)-dependent Regulation of Bcl-2 and Tissue Inhibitor of Metalloproteinase (TIMP)-1 in Coronary Endothelial Cells Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2009 | Pubmed ID: 19910689 Ischemic Injury and the Parathyroid Hormone-related Protein System: Friend or Foe? Basic Research in Cardiology. Jul, 2009 | Pubmed ID: 19377853 Post-conditioning Restores Pre-ischaemic Receptor Coupling in Rat Isolated Hearts British Journal of Pharmacology. Mar, 2009 | Pubmed ID: 19366352 Cell-specific Effects of Nitric Oxide Deficiency on Parathyroid Hormone-related Peptide (PTHrP) Responsiveness and PTH1 Receptor Expression in Cardiovascular Cells Endocrinology. Aug, 2009 | Pubmed ID: 19342458 Effect of Preischemic Beta-adrenoceptor Stimulation on Postischemic Contractile Dysfunction Life Sciences. Mar, 2009 | Pubmed ID: 19302819 Stimulation of CGMP Signalling Protects Coronary Endothelium Against Reperfusion-induced Intercellular Gap Formation Cardiovascular Research. Jul, 2009 | Pubmed ID: 19234300 Parathyroid Hormone Improves Contractile Performance of Adult Rat Ventricular Cardiomyocytes at Low Concentrations in a Non-acute Way Cardiovascular Research. Apr, 2009 | Pubmed ID: 19168854 CGRP-alpha Responsiveness of Adult Rat Ventricular Cardiomyocytes from Normotensive and Spontaneously Hypertensive Rats European Journal of Cell Biology. Apr, 2009 | Pubmed ID: 19128857 Angiotensin II-dependent Loss of Cardiac Function: Mechanisms and Pharmacological Targets Attenuating This Effect Journal of Cellular Physiology. Oct, 2008 | Pubmed ID: 18528823 Stem Cell Mobilization Versus Stem Cell Homing: Potential Role for Parathyroid Hormone? Cardiovascular Research. Mar, 2008 | Pubmed ID: 18194991 Sarcoplasmic Reticulum-mitochondrial Interaction in the Mechanism of Acute Reperfusion Injury. Viewpoint Cardiovascular Research. Jan, 2008 | Pubmed ID: 18006433 Parathyroid Hormone-related Protein (PTHrP) Signal Cascade Modulates Myocardial Dysfunction in the Pressure Overloaded Heart European Journal of Heart Failure. Dec, 2007 | Pubmed ID: 17997355 The Acute Phase Protein Alpha2-macroglobulin Induces Rat Ventricular Cardiomyocyte Hypertrophy Via ERK1,2 and PI3-kinase/Akt Pathways Cardiovascular Research. Jul, 2007 | Pubmed ID: 17412314 On the Role of Junctin in Cardiac Ca2+ Handling, Contractility, and Heart Failure American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2007 | Pubmed ID: 17400717 Vasodilatory Effect of Tuberoinfundibular Peptide (TIP39): Requirement of Receptor Desensitization and Its Beneficial Effect in the Post-ischemic Heart Peptides. Apr, 2007 | Pubmed ID: 17222942 Impaired Release of Bioactive Parathyroid Hormone-related Peptide in Patients with Pulmonary Hypertension and Endothelial Dysfunction Journal of Vascular Research. 2007 | Pubmed ID: 17191022 Contractile Performance of Adult Ventricular Rat Cardiomyocytes is Not Directly Jeopardized by NO/cGMP-dependent Induction of Pro-apoptotic Pathways Journal of Molecular and Cellular Cardiology. Feb, 2007 | Pubmed ID: 17157310 Lack of Endothelial Nitric Oxide Synthase-derived Nitric Oxide Formation Favors Hypertrophy in Adult Ventricular Cardiomyocytes Hypertension (Dallas, Tex. : 1979). Jan, 2007 | Pubmed ID: 17075027 N-terminal Parathyroid Hormone-related Peptide Hyperpolarizes Endothelial Cells and Causes a Reduction of the Coronary Resistance of the Rat Heart Via Endothelial Hyperpolarization Peptides. Nov, 2006 | Pubmed ID: 16806582 Contribution of PI 3-kinase Isoforms to Angiotensin II- and Alpha-adrenoceptor-mediated Signalling Pathways in Cardiomyocytes Cardiovascular Research. Jul, 2006 | Pubmed ID: 16750184 Insulin Protects Cardiomyocytes Against Reoxygenation-induced Hypercontracture by a Survival Pathway Targeting SR Ca2+ Storage Cardiovascular Research. May, 2006 | Pubmed ID: 16569400 PKC-independent Signal Transduction Pathways Increase SERCA2 Expression in Adult Rat Cardiomyocytes Journal of Molecular and Cellular Cardiology. Dec, 2005 | Pubmed ID: 16236312 No Correlation Between the P38 MAPK Pathway and the Contractile Dysfunction in Diabetic Cardiomyocytes: Hyperglycaemia-induced Signalling and Contractile Function Pflugers Archiv : European Journal of Physiology. Nov, 2005 | Pubmed ID: 16041601 The Influence of Oestrogen-deficiency and ACE Inhibition on the Progression of Myocardial Hypertrophy in Spontaneously Hypertensive Rats European Journal of Heart Failure. Dec, 2005 | Pubmed ID: 15922661 P38 MAP-kinase in Cultured Adult Rat Ventricular Cardiomyocytes: Expression and Involvement in Hypertrophic Signalling European Journal of Heart Failure. Jun, 2005 | Pubmed ID: 15921779 Cardiac-specific Effects of Parathyroid Hormone-related Peptide: Modification by Aging and Hypertension Cardiovascular Research. May, 2005 | Pubmed ID: 15820202 Enantioselective Actions of Bupivacaine and Ropivacaine on Coronary Vascular Resistance at Cardiotoxic Concentrations Anesthesia and Analgesia. Mar, 2005 | Pubmed ID: 15728056 Which Papers Are Most Interesting to the Readers of Cardiovascular Research? Information from Download Monitoring Cardiovascular Research. Jan, 2005 | Pubmed ID: 15621025 Adult Ventricular Cardiomyocytes: Isolation and Culture Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 15361670 Inhibition of Ca2+-dependent PKC Isoforms Unmasks ERK-dependent Hypertrophic Growth Evoked by Phenylephrine in Adult Ventricular Cardiomyocytes Cardiovascular Research. Aug, 2004 | Pubmed ID: 15276481 Synchronization and Integration of Multiple Hypertrophic Pathways in the Heart Cardiovascular Research. Aug, 2004 | Pubmed ID: 15276461 Sex-specific Differences in Ventricular Expression and Function of Parathyroid Hormone-related Peptide Cardiovascular Research. Feb, 2004 | Pubmed ID: 14736547 Reoxygenation-induced Rigor-type Contracture Journal of Molecular and Cellular Cardiology. Dec, 2003 | Pubmed ID: 14654374 Mechanism of the Positive Contractile Effect of Nitric Oxide on Rat Ventricular Cardiomyocytes with Positive Force/frequency Relationship Pflugers Archiv : European Journal of Physiology. Dec, 2003 | Pubmed ID: 14586658 Left Ventricular Hypertrophy in Rats with Biliary Cirrhosis Hepatology (Baltimore, Md.). Sep, 2003 | Pubmed ID: 12939585 Parathyroid Hormone-related Peptide is Induced by Stimulation of Alpha 1A-adrenoceptors and Improves Resistance Against Apoptosis in Coronary Endothelial Cells Molecular Pharmacology. Jan, 2003 | Pubmed ID: 12488543 Parathyroid Hormone-related Peptide Improves Contractile Function of Stunned Myocardium in Rats and Pigs American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2003 | Pubmed ID: 12485816 Mechanosensitive Release of Parathyroid Hormone-related Peptide from Coronary Endothelial Cells American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2002 | Pubmed ID: 12234801 Alterations of Beta-adrenergic Signaling and Cardiac Hypertrophy in Transgenic Mice Overexpressing TGF-beta(1) American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2002 | Pubmed ID: 12181157 Hypertrophic Responsiveness of Cardiomyocytes to Alpha- or Beta-adrenoceptor Stimulation Requires Sodium-proton-exchanger-1 (NHE-1) Activation but Not Cellular Alkalization European Journal of Heart Failure. Jun, 2002 | Pubmed ID: 12034148 Neuropeptide Y Modifies the Hypertrophic Response of Adult Ventricular Cardiomyocytes to Norepinephrine Cardiovascular Research. Mar, 2002 | Pubmed ID: 11922898 Specific Role for the Extracellular Signal-regulated Kinase Pathway in Angiotensin II- but Not Phenylephrine-induced Cardiac Hypertrophy in Vitro Pflugers Archiv : European Journal of Physiology. Jan, 2002 | Pubmed ID: 11810220 Isolation and Cultivation of Adult Rat Cardiomyocytes Franziska Nippert1, Rolf Schreckenberg1, Klaus-Dieter Schlüter1 1Institute of Physiology, Justus Liebig University Giessen JoVE 56634 Medicina
Isolation and Cultivation of Adult Rat Cardiomyocytes Franziska Nippert1, Rolf Schreckenberg1, Klaus-Dieter Schlüter1 1Institute of Physiology, Justus Liebig University Giessen JoVE 56634 Medicina