Martini Clift Medical School Swansea University Biography Publications Institution JoVE Articles Martini Clift Martin gained his PhD at Edinburgh Napier University in 2009, in Nanoparticle In Vitro Toxicolog. From 2008 to 2015, Martin spent his post-doctoral studies in Switzerland at both the University of Bern, as well as the Adolphe Merkle Institute, University of Fribourg. Martin joined Swansea University Medical School in Dec 2015. Martin has a core competence in particle and fibre toxicology. Martin’s research is focused on the nanoparticle-(mammalian)cell interaction, with a view to determining the mechanistic toxicological, immunological and genotoxic effects that nanoparticles, with varying physico-chemcial characteristics, may cause at the cellular level by using advanced, next-level in vitro systems combined with state-of-the-art microscopy and bioanalytical approaches. Special interests include the ability for nanoparticle geometry and surface properties to interfere with the human immune system and bloodstream. Another clear ambition of Martin's research is to create, study and promote alternative in vitro models that mimic in vivo environments, in order to gain a mechanistic understanding of how nanoparticles may, potentially, adversely impact human health. Special focus is also given to creating disease-based in vitro models and the role nanoparticles play in disease onsert and/or exacerbation. Martin has >100 publications within the field of nanotoxicology and the nanoparticle-cell interaction in vitro. Publications Uterine Infection Alters the Transcriptome of the Bovine Reproductive Tract Three Months Later Reproduction (Cambridge, England). Jul, 2020 | Pubmed ID: 32422601 Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety Chemical Research in Toxicology. May, 2020 | Pubmed ID: 32307980 Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy Nanomaterials (Basel, Switzerland). Dec, 2019 | Pubmed ID: 31835823 Assessment of the Potential for In-plume Sulphur Dioxide Gas-ash Interactions to Influence the Respiratory Toxicity of Volcanic Ash Environmental Research. 12, 2019 | Pubmed ID: 31629947 Biological Response of an in Vitro Human 3D Lung Cell Model Exposed to Brake Wear Debris Varies Based on Brake Pad Formulation Archives of Toxicology. 07, 2018 | Pubmed ID: 29748788 Respiratory Hazard Assessment of Combined Exposure to Complete Gasoline Exhaust and Respirable Volcanic Ash in a Multicellular Human Lung Model at the Air-liquid Interface Environmental Pollution (Barking, Essex : 1987). Jul, 2018 | Pubmed ID: 29455917 Aligning Nanotoxicology with the 3Rs: What is Needed to Realise the Short, Medium and Long-term Opportunities? Regulatory Toxicology and Pharmacology : RTP. Dec, 2017 | Pubmed ID: 29069581 Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge Environmental Health Perspectives. 10, 2017 | Pubmed ID: 29017987 A Novel Technique to Determine the Cell Type Specific Response Within an in Vitro Co-culture Model Via Multi-colour Flow Cytometry Scientific Reports. 03, 2017 | Pubmed ID: 28348366 Critical Review of the Current and Future Challenges Associated with Advanced in Vitro Systems Towards the Study of Nanoparticle (secondary) Genotoxicity Mutagenesis. 01, 2017 | Pubmed ID: 27815329 Combined Exposure of Diesel Exhaust Particles and Respirable Soufrière Hills Volcanic Ash Causes a (pro-)inflammatory Response in an in Vitro Multicellular Epithelial Tissue Barrier Model Particle and Fibre Toxicology. 12, 2016 | Pubmed ID: 27955700 A Critical Review of the Current Knowledge Regarding the Biological Impact of Nanocellulose Journal of Nanobiotechnology. Dec, 2016 | Pubmed ID: 27903280 장기 나노 물질 노출 다음 체외 물질 독성 테스트를 위한 고급 3D 간 모델 Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioingegneria
장기 나노 물질 노출 다음 체외 물질 독성 테스트를 위한 고급 3D 간 모델 Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioingegneria