Shareen H. Doak In vitro Toxicology Group Swansea University Medical School Biography Publications Institution JoVE Articles Shareen H. Doak has not added a biography. If you are Shareen H. Doak and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of Passive-dosed and Solvent Spiked Exposures of Pro-carcinogen, Benzo[a]pyrene, to Human Lymphoblastoid Cell Line, MCL-5 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Jun, 2020 | Pubmed ID: 32497684 Nanomaterials and Innate Immunity: A Perspective of the Current Status in Nanosafety Chemical Research in Toxicology. May, 2020 | Pubmed ID: 32307980 Use of in Vitro 3D Tissue Models in Genotoxicity Testing: Strategic Fit, Validation Status and Way Forward. Report of the Working Group from the 7 International Workshop on Genotoxicity Testing (IWGT) Mutation Research. Feb - Mar, 2020 | Pubmed ID: 32247552 Emerging Standards and Analytical Science for Nanoenabled Medical Products Annual Review of Analytical Chemistry (Palo Alto, Calif.). Feb, 2020 | Pubmed ID: 32084321 Horizon Scanning for Novel and Emerging in Vitro Mammalian Cell Mutagenicity Test Systems Mutation Research. 11, 2019 | Pubmed ID: 31699342 Genotoxicity Assessment of Nanomaterials: Recommendations on Best Practices, Assays, and Methods Toxicological Sciences : an Official Journal of the Society of Toxicology. 08, 2018 | Pubmed ID: 29701824 STEAP2 Knockdown Reduces the Invasive Potential of Prostate Cancer Cells Scientific Reports. 04, 2018 | Pubmed ID: 29674723 A Novel, Integrated in Vitro Carcinogenicity Test to Identify Genotoxic and Non-genotoxic Carcinogens Using Human Lymphoblastoid Cells Archives of Toxicology. Feb, 2018 | Pubmed ID: 29110037 Characterizing Nanoparticles in Biological Matrices: Tipping Points in Agglomeration State and Cellular Delivery In Vitro ACS Nano. 12, 2017 | Pubmed ID: 29072897 Aligning Nanotoxicology with the 3Rs: What is Needed to Realise the Short, Medium and Long-term Opportunities? Regulatory Toxicology and Pharmacology : RTP. Dec, 2017 | Pubmed ID: 29069581 Exposure to Engineered Nanomaterials: Impact on DNA Repair Pathways International Journal of Molecular Sciences. Jul, 2017 | Pubmed ID: 28703770 The Role of Intracellular Trafficking of CdSe/ZnS QDs on Their Consequent Toxicity Profile Journal of Nanobiotechnology. Jun, 2017 | Pubmed ID: 28619032 Choose Your Cell Model Wisely: The in Vitro Nanoneurotoxicity of Differentially Coated Iron Oxide Nanoparticles for Neural Cell Labeling Acta Biomaterialia. 06, 2017 | Pubmed ID: 28373085 Tissue-Engineered Solutions in Plastic and Reconstructive Surgery: Principles and Practice Frontiers in Surgery. 2017 | Pubmed ID: 28280722 Critical Review of the Current and Future Challenges Associated with Advanced in Vitro Systems Towards the Study of Nanoparticle (secondary) Genotoxicity Mutagenesis. 01, 2017 | Pubmed ID: 27815329 Is Nickel Chloride Really a Non-Genotoxic Carcinogen? Basic & Clinical Pharmacology & Toxicology. Sep, 2017 | Pubmed ID: 27748567 Factors Affecting the in Vitro Micronucleus Assay for Evaluation of Nanomaterials Mutagenesis. 01, 2017 | Pubmed ID: 27567283 Emerging Metrology for High-throughput Nanomaterial Genotoxicology Mutagenesis. 01, 2017 | Pubmed ID: 27565834 Genetic Toxicity Assessment of Engineered Nanoparticles Using a 3D in Vitro Skin Model (EpiDerm™) Particle and Fibre Toxicology. 09, 2016 | Pubmed ID: 27613375 Opinion of the Scientific Committee on Consumer Safety (SCCS) - Opinion on the Use of 2,2'-methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) (nano) - S79 - In Cosmetic Products Regulatory Toxicology and Pharmacology : RTP. Apr, 2016 | Pubmed ID: 26776753 Empirical Analysis of BMD Metrics in Genetic Toxicology Part I: in Vitro Analyses to Provide Robust Potency Rankings and Support MOA Determinations Mutagenesis. 05, 2016 | Pubmed ID: 26687511 Genotoxic Capacity of Cd/Se Semiconductor Quantum Dots with Differing Surface Chemistries Mutagenesis. Jan, 2016 | Pubmed ID: 26275419 Cell Type-dependent Changes in CdSe/ZnS Quantum Dot Uptake and Toxic Endpoints Toxicological Sciences : an Official Journal of the Society of Toxicology. Apr, 2015 | Pubmed ID: 25601991 Real-time Reverse-transcription Polymerase Chain Reaction: Technical Considerations for Gene Expression Analysis Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22147577 In Vitro Genotoxicity Testing Strategy for Nanomaterials and the Adaptation of Current OECD Guidelines Mutation Research. Jun, 2012 | Pubmed ID: 21971291 Confounding Experimental Considerations in Nanogenotoxicology Mutagenesis. Jul, 2009 | Pubmed ID: 19351890 No-observed Effect Levels Are Associated with Up-regulation of MGMT Following MMS Exposure Mutation Research. Dec, 2008 | Pubmed ID: 18992265 High-resolution Imaging Using a Novel Atomic Force Microscope and Confocal Laser Scanning Microscope Hybrid Instrument: Essential Sample Preparation Aspects Histochemistry and Cell Biology. Nov, 2008 | Pubmed ID: 18719934 Aneuploidy in Upper Gastro-intestinal Tract Cancers--a Potential Prognostic Marker? Mutation Research. Mar, 2008 | Pubmed ID: 18093868 Bone Morphogenic Factor Gene Dosage Abnormalities in Prostatic Intraepithelial Neoplasia and Prostate Cancer Cancer Genetics and Cytogenetics. Jul, 2007 | Pubmed ID: 17656261 Mechanistic Influences for Mutation Induction Curves After Exposure to DNA-reactive Carcinogens Cancer Research. Apr, 2007 | Pubmed ID: 17440105 Generation of Locus-specific Probes for Interphase Fluorescence in Situ Hybridisation--application in Barrett's Esophagus Experimental and Molecular Pathology. Aug, 2004 | Pubmed ID: 15215047 Differential Expression of the MAD2, BUB1 and HSP27 Genes in Barrett's Oesophagus-their Association with Aneuploidy and Neoplastic Progression Mutation Research. Mar, 2004 | Pubmed ID: 15013707 Utilisation of the STEAP Protein Family in a Diagnostic Setting May Provide a More Comprehensive Prognosis of Prostate Cancer PloS One. | Pubmed ID: 31393902 In Vitro Detection of in Vitro Secondary Mechanisms of Genotoxicity Induced by Engineered Nanomaterials Particle and Fibre Toxicology. | Pubmed ID: 30760282 Investigating FlowSight® Imaging Flow Cytometry As a Platform to Assess Chemically Induced Micronuclei Using Human Lymphoblastoid Cells in Vitro Mutagenesis. | Pubmed ID: 30204902 장기 나노 물질 노출 다음 체외 물질 독성 테스트를 위한 고급 3D 간 모델 Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioingegneria
장기 나노 물질 노출 다음 체외 물질 독성 테스트를 위한 고급 3D 간 모델 Samantha V. Llewellyn1, Gillian E. Conway1, Ume-Kulsoom Shah1, Stephen J. Evans1, Gareth J.S. Jenkins1, Martin J.D. Clift1, Shareen H. Doak1 1In vitro Toxicology Group, Swansea University Medical School JoVE 61141 Bioingegneria