Masaaki Higashiyama Department of internal medicine National Defense Medical College Biography Publications Institution JoVE Articles Masaaki Higashiyama has not added a biography. If you are Masaaki Higashiyama and would like to personalize this page please email our Author Liaison for assistance. Publications Redox-dependent PPARγ/Tnpo1 Complex Formation Enhances PPARγ Nuclear Localization and Signaling Free Radical Biology & Medicine. Jun, 2020 | Pubmed ID: 32553752 [Role of Immunomodulators on Treatment of Patients with Inflammatory Bowel Diseases in Special Occasions, Pregnancy or Elderly] Nihon Shokakibyo Gakkai Zasshi = The Japanese Journal of Gastro-enterology. 2020 | Pubmed ID: 32161244 Dietary Emulsifier Polysorbate-80-induced Small-intestinal Vulnerability to Indomethacin-induced Lesions Via Dysbiosis Journal of Gastroenterology and Hepatology. Jan, 2020 | Pubmed ID: 31359491 Correction To: Management of Elderly Ulcerative Colitis in Japan Journal of Gastroenterology. Oct, 2019 | Pubmed ID: 31392487 Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice Hepatology Communications. Aug, 2019 | Pubmed ID: 31388630 Chitinase 3-like 1 Deficiency Ameliorates Liver Fibrosis by Promoting Hepatic Macrophage Apoptosis Hepatology Research : the Official Journal of the Japan Society of Hepatology. Nov, 2019 | Pubmed ID: 31250532 Management of Elderly Ulcerative Colitis in Japan Journal of Gastroenterology. Jul, 2019 | Pubmed ID: 31025187 Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma Internal Medicine (Tokyo, Japan). Jul, 2019 | Pubmed ID: 30918171 Depression Promotes the Onset of Irritable Bowel Syndrome Through Unique Dysbiosis in Rats Gut and Liver. 05, 2019 | Pubmed ID: 30602220 Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy Internal Medicine (Tokyo, Japan). Feb, 2019 | Pubmed ID: 30210116 Nicotine Treatment Ameliorates DSS-induced Colitis by Suppressing MAdCAM-1 Expression and Leukocyte Recruitment Journal of Leukocyte Biology. 11, 2018 | Pubmed ID: 29901817 Clinical Differences Between Elderly-onset Ulcerative Colitis and Non-elderly-onset Ulcerative Colitis: A Nationwide Survey Data in Japan Journal of Gastroenterology and Hepatology. Nov, 2018 | Pubmed ID: 29669163 Amelioration of Colitis Through Blocking Lymphocytes Entry to Peyer's Patches by Sphingosine-1-phosphate Lyase Inhibitor Journal of Gastroenterology and Hepatology. Jan, 2018 | Pubmed ID: 29336057 Vitamin A-coupled Liposome System Targeting Free Cholesterol Accumulation in Hepatic Stellate Cells Offers a Beneficial Therapeutic Strategy for Liver Fibrosis Hepatology Research : the Official Journal of the Japan Society of Hepatology. Apr, 2018 | Pubmed ID: 29243365 Human Intestinal Spirochetosis Mimicking Ulcerative Colitis Clinical Journal of Gastroenterology. Apr, 2018 | Pubmed ID: 29204849 Evaluation by MR Enterocolonography of Lansoprazole-induced Collagenous Colitis Accompanied with Protein-losing Enteropathy Internal Medicine (Tokyo, Japan). Jan, 2018 | Pubmed ID: 29033425 Novel Probiotics Isolated from a Japanese Traditional Fermented Food, Funazushi, Attenuates DSS-induced Colitis by Increasing the Induction of High Integrin αv/β8-expressing Dendritic Cells Journal of Gastroenterology. Mar, 2018 | Pubmed ID: 28631049 Uric Acid Ameliorates Indomethacin-induced Enteropathy in Mice Through Its Antioxidant Activity Journal of Gastroenterology and Hepatology. Nov, 2017 | Pubmed ID: 28295549 Psychological Stress Exacerbates NSAID-induced Small Bowel Injury by Inducing Changes in Intestinal Microbiota and Permeability Via Glucocorticoid Receptor Signaling Journal of Gastroenterology. Jan, 2017 | Pubmed ID: 27075753 Platelet Interaction with Lymphatics Aggravates Intestinal Inflammation by Suppressing Lymphangiogenesis American Journal of Physiology. Gastrointestinal and Liver Physiology. 08, 2016 | Pubmed ID: 27313177 Recombinant Thrombomodulin Modulates Murine Colitis Possibly Via High-Mobility Group Box 1 Protein Inhibition Digestion. 2015 | Pubmed ID: 26302768 Lethal Hemorrhage from Duodenal Ulcer Due to Small Pancreatic Cancer Clinical Journal of Gastroenterology. Aug, 2015 | Pubmed ID: 26253020 Toll-like Receptor (TLR) 2 Agonists Ameliorate Indomethacin-induced Murine Ileitis by Suppressing the TLR4 Signaling Journal of Gastroenterology and Hepatology. Nov, 2015 | Pubmed ID: 25867219 Beneficial Effect of an Omega-6 PUFA-rich Diet in Non-steroidal Anti-inflammatory Drug-induced Mucosal Damage in the Murine Small Intestine World Journal of Gastroenterology. Jan, 2015 | Pubmed ID: 25574090 Phlebosclerotic Colitis That Was Difficult to Distinguish from Collagenous Colitis Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society. Jul, 2014 | Pubmed ID: 23902595 Prevalence of Serum Celiac Antibody in Patients with IBD in Japan Journal of Gastroenterology. May, 2014 | Pubmed ID: 23754511 Involvement of Autotaxin/lysophospholipase D Expression in Intestinal Vessels in Aggravation of Intestinal Damage Through Lymphocyte Migration Laboratory Investigation; a Journal of Technical Methods and Pathology. May, 2013 | Pubmed ID: 23478591 Endoscopic Finding of Spontaneous Hemorrhage Correlates with Tumor Necrosis Factor Alpha Expression in Colonic Mucosa of Patients with Ulcerative Colitis International Journal of Colorectal Disease. Aug, 2013 | Pubmed ID: 23377880 Dietary Lipids and Sweeteners Regulate Glucagon-like Peptide-2 Secretion American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2013 | Pubmed ID: 23370677 Indomethacin-induced Small Intestinal Injury is Ameliorated by Cilostazol, a Specific PDE-3 Inhibitor Scandinavian Journal of Gastroenterology. Sep, 2012 | Pubmed ID: 22934593 HIF-1 in T Cells Ameliorated Dextran Sodium Sulfate-induced Murine Colitis Journal of Leukocyte Biology. Jun, 2012 | Pubmed ID: 22457366 Physiological Stress Exacerbates Murine Colitis by Enhancing Proinflammatory Cytokine Expression That is Dependent on IL-18 American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2011 | Pubmed ID: 21719737 Trial to Control an Outbreak of Panton-Valentine Leukocidin-positive Methicillin-resistant Staphylococcus Aureus at a Boarding School in Japan American Journal of Infection Control. Dec, 2011 | Pubmed ID: 21658811 Cilostazol, a Specific PDE-3 Inhibitor, Ameliorates Chronic Ileitis Via Suppression of Interaction of Platelets with Monocytes American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2009 | Pubmed ID: 19815627 Long-term Outcome of Endoscopic Semiconductive Diode Laser Irradiation Therapy with Injection of Indocyanine Green for Early Gastric Cancer Journal of Gastroenterology and Hepatology. Aug, 2008 | Pubmed ID: 18624897 P-selectin-dependent Monocyte Recruitment Through Platelet Interaction in Intestinal Microvessels of LPS-treated Mice Microcirculation (New York, N.Y. : 1994). Jul, 2008 | Pubmed ID: 18574746 Expression of PD-1, PD-L1, and PD-L2 in the Liver in Autoimmune Liver Diseases The American Journal of Gastroenterology. Feb, 2007 | Pubmed ID: 17311651 [A Case of Churg-Strauss Syndrome Discovered with Hematemesis] Nihon Shokakibyo Gakkai Zasshi = The Japanese Journal of Gastro-enterology. Dec, 2006 | Pubmed ID: 17148925 [Alcoholic Ketoacidosis with Severe Abdominal Pain] Nihon Naika Gakkai Zasshi. The Journal of the Japanese Society of Internal Medicine. Jul, 2006 | Pubmed ID: 16893031 Microscopic Observation of Lymphocyte Dynamics in Rat Peyer's Patches Kazuhiko Shirakabe1,2, Masaaki Higashiyama1, Naoki Shibuya2, Kazuki Horiuchi1, Masayuki Saruta2, Ryota Hokari1 1Department of internal medicine, National Defense Medical College, 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medicine JoVE 61568 Medicina
Microscopic Observation of Lymphocyte Dynamics in Rat Peyer's Patches Kazuhiko Shirakabe1,2, Masaaki Higashiyama1, Naoki Shibuya2, Kazuki Horiuchi1, Masayuki Saruta2, Ryota Hokari1 1Department of internal medicine, National Defense Medical College, 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medicine JoVE 61568 Medicina