Screening Lipid Structures Using Stable Isotope Labeling

August 23, 2024

安定同位体標識 LC-TIMS-TOF MS/MS を用いた de novo 脂質の追跡

Calibration of the Mass Spectrometer for Screening Lipids with Stable Isotope Labeling by LC-TIMS-TOF MS/MS

LC-TIMS-TOF MS/MS Data Analysis for Screening Lipids with Stable Isotope Labeling

Katherine D. Castro, Lilian Valadares Tose, Matthew Willetts, Melvin A. Park, Marcela Nouzova, Fernando G. Noriega⁵, Francisco Fernandez-Lima⁶

¹Deparment of Chemistry and Biochemistry,Florida International University, ²Bruker Daltonics Inc., ³Institute of Parasitology,Biology Centre CAS, ⁴Department of Biological Sciences,Florida International University, ⁵Department of Parasitology,University of South Bohemia, ⁶Biomolecular Sciences Institute,Florida International University

Summary

ここでは、安定同位体標識により、その保持時間、移動度、およびフラグメンテーションを利用した脂質構造をスクリーニングする方法を紹介します。

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