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Bioengineering

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JoVE Journal Bioengineering
Fabrication of Micro-tissues using Modules of Collagen Gel Containing Cells
 
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Fabrication of Micro-tissues using Modules of Collagen Gel Containing Cells

Article DOI: 10.3791/2177-v • 09:29 min • December 13th, 2010
December 13th, 2010 •
1, 1, 1, 2, 1, 2, 1, 2, 2, 2, 1
1Institute of Biomaterials and Biomedical Engineering / Department of Chemical Engineering and Applied Chemistry, University of Toronto, 2Institute of Biomaterials and Biomedical Engineering, University of Toronto

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Creation of micro-tissues using cylindrical collagen gels, called modules, that contain embedded cells and which surface is coated with endothelial cells.

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Fabrication Micro-tissues Modules Collagen Gel Cells Uniform Scalable Vascularized Tissues Gelable Materials Crosslinkable Materials Size Shrinkage Endothelial Cells Diffusion Limit Oxygen Nutrients Perfusable Tissues Modular Construction Cell Types Neutralizing Collagen Embedding Cells Gelling Collagen Cutting Modules Coating Endothelial Cells
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