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Neuroscience

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An Engulfment Assay
 

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons

Article DOI: 10.3791/51482-v 07:38 min June 8th, 2014
June 8th, 2014

Capitoli

Riepilogo

Microglia are the resident immune cells of the central nervous system (CNS) with a high capacity to phagocytose or engulf material in their extracellular environment. Here, a broadly applicable, reliable, and highly quantitative assay for visualizing and measuring microglia-mediated engulfment of synaptic components is described.

Tags

Keywords: Phagocytosis Microglia CNS Engulfment Assay Neurodegenerative Disease Synaptic Pruning Retinogeniculate System Astrocytes Macrophages Synaptic Remodeling
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