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Cancer Research

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A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
 

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Article DOI: 10.3791/55271-v 07:59 min March 4th, 2017
March 4th, 2017

Capitoli

Riepilogo

The poor understanding of the in vivo performance of nanomedicines stymies their clinical translation. Procedures to evaluate the in vivo behavior of cancer nanomedicines at systemic, tissue, single-cell, and subcellular levels in tumor-bearing immunocompetent mice are described here. This approach may help researchers to identify promising cancer nanomedicines for clinical translation.

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Keywords: Cancer Nanomedicines In Vivo Performance Tumor-bearing Mice Dual-labeling Approach Liposomes Lipophilic Cationic Fluorescent Dye Phosphate-buffered Saline Dynamic Light Scattering Radiolabeling Zirconium-89 Oxalate Size-exclusion HPLC Radiochemical Purity
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