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Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
 

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

Article DOI: 10.3791/56015-v • 08:43 min • August 7th, 2017
August 7th, 2017 •
1, 2, 3, 1, 3, 2, 3
1Zhejiang Chinese Medical University, 2Department of Psychiatry, Zhejiang Provincial People's Hospital, 3Department of Radiology, Zhejiang Provincial People's Hospital

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Based on resting-state functional magnetic resonance imaging with Granger causality analysis, we investigated the alterations in the directed functional connectivity between the posterior cingulate cortex and whole brain in patients with Alzheimer's Disease (AD), patients with Mild Cognitive Impairment (MCI), and healthy controls.

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Keywords: Granger Causality Analysis Directed Functional Connectivity Alzheimer's Disease Mild Cognitive Impairment FMRI PCC Diagnosis Progression EEG Preprocessing DicomToNifti Slice Timing Realignment Normalization Segmentation Smoothing
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