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Immunology and Infection

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JoVE Journal Immunology and Infection
Brug af invertebrate Galleria mellonella som en infektions model til undersøgelse af Mycobacterium tuberkulose komplekset
 
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Brug af invertebrate Galleria mellonella som en infektions model til undersøgelse af Mycobacterium tuberkulose komplekset

Article DOI: 10.3791/59703-v • 09:23 min • June 30th, 2019
June 30th, 2019 •
*1, *1, 1,2, 1, 3, *1, *1
1Section of Pediatric Infectious Diseases and Allergy, Department of Medicine, Imperial College London, 2Department of Pharmacy, National University of Singapore, 3MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London
* These authors contributed equally

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Galleria mellonella blev for nylig etableret som en reproducerbar, billig, og etisk acceptabel infektion model for Mycobacterium tuberkulose kompleks. Her beskriver og demonstrerer vi de skridt, der er taget for at etablere en vellykket infektion af G. mellonella med bioluminescent Mycobacterium bovis BCG Lux.

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Immunologi og infektion Galleria mellonella mycobakterier tuberkulose Mycobacterium bovis BCG Lux infektion model Host-pathogen interaktioner Mycobacterium tuberkulose kompleks hemocytes
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