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Journal / Cancer Research / Genome-Wide Analysis of DNA Methylation in…
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Cancer Research

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JoVE Journal Cancer Research
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
 

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

Article DOI: 10.3791/61355-v • 07:50 min • September 18th, 2020
September 18th, 2020 •
1,2, 2, 1,3, 3, 3, 2, 1
1Department of Surgery, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 2Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 3Department of Surgery, Juntendo University Shizuoka Hospital

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Herein, we describe a procedure for genome-wide analysis of DNA methylation in gastrointestinal cancers. The procedure is of relevance to studies that investigate relationships between methylation patterns of genes and factors contributing to carcinogenesis in gastrointestinal cancers.

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Keywords: DNA Methylation Genome-wide Analysis Gastrointestinal Cancer Epigenetic Biomarkers LA Platform Complex Aberration Formalin-fixed Paraffin Embedded Macrodissection Bisulfite Conversion
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