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Cancer Research

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JoVE Journal Cancer Research
Dynamische beeldvorming van chimere antigeenreceptor T-cellen met [18F]Tetrafluoroboraat positronemissietomografie/computertomografie
 
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Dynamische beeldvorming van chimere antigeenreceptor T-cellen met [18F]Tetrafluoroboraat positronemissietomografie/computertomografie

Article DOI: 10.3791/62334-v • 09:34 min • February 17th, 2022
February 17th, 2022 •
1,2, 1,2, 3, 1,2,4,5, 1,2, 3, 3, 3, 3, 1,2, 1,2,5,6
1T Cell Engineering, Mayo Clinic, 2Division of Hematology, Mayo Clinic, 3Department of Radiology, Mayo Clinic, 4Regenerative Sciences PhD, Mayo Clinic, 5Department of Molecular Medicine, Mayo Clinic, 6Department of Immunology, Mayo Clinic

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Dit protocol beschrijft de methodologie voor het niet-invasief volgen van T-cellen die genetisch gemanipuleerd zijn om chimere antigeenreceptoren in vivo tot expressie te brengen met een klinisch beschikbaar platform.

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Cancer Research CAR T cell NIS reporter [18F]TFB-PET non-invasive imaging
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