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3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis
 

3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis

Article DOI: 10.3791/63106-v • 06:46 min • February 25th, 2022
February 25th, 2022 •
1, 1, 1, 1
1Gastroenterology and Hepatology, Stanford University

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The present protocol optimizes the liver in situ perfusion/decellularization and two-photon microscopy methods to establish a reliable platform to visualize the dynamics of extracellular matrix (ECM) remodeling during non-alcoholic steatohepatitis (NASH).

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Keywords: 3D Imaging Liver Extracellular Matrix Mouse Model Non-alcoholic Steatohepatitis NASH Fibrosis Cirrhosis Liver Cancer ECM Remodeling Portal Vein Catheterization Perfusion Sodium Deoxycholate
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