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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
 

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Article DOI: 10.3791/63451-v • 08:40 min • January 20th, 2022
January 20th, 2022 •
1,2, 1,2, 1,2, 1,2
1INRAE, UR BIA, F-44316 Nantes, France, 2INRAE, BIBS Facility, F-44316 Nantes, France

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Ion mobility spectrometry (IMS) is an interesting complement to mass spectrometry for the characterization of biomolecules, notably because it is sensitive to isomerism. This protocol describes a tandem IMS (IMS/IMS) experiment, which allows the isolation of a molecule and the generation of the mobility profiles of its fragments.

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Keywords: Cyclic Ion Mobility Spectrometer Tandem Ion Mobility Glycan Classification Molecular Networks Mass Spectrometry Ion Mobility Arrival Time Calibration Acquisition Settings TOF Mode MSMS Mode
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