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JoVE Journal Neuroscience
An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
 

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Article DOI: 10.3791/64863-v • 08:59 min • March 3rd, 2023
March 3rd, 2023 •
1,2, 1, 1, 1, 1, 1,2, 1,2
1Division of Systems Neuroscience, New York State Psychiatric Institute, 2Department of Psychiatry, Columbia University

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Here, we present a simplified open-source hardware and software setup for investigating mouse spatial learning using virtual reality (VR). This system displays a virtual linear track to a head-restrained mouse running on a wheel by utilizing a network of microcontrollers and a single-board computer running an easy-to-use Python graphical software package.

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Keywords: Virtual Reality Spatial Learning Head-restrained Mice Open-source System Modular Electronic Setup Rotary Encoder ESP32 Serial Communication Solenoid Valve Lick Port Single Board Computer GPU Projection Screen
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