Balázs Gereben Laboratory of Molecular Cell Metabolism Institute of Experimental Medicine Biography Publications Institution JoVE Articles Balázs Gereben has not added a biography. If you are Balázs Gereben and would like to personalize this page please email our Author Liaison for assistance. Publications Axonal T3 Uptake and Transport Can Trigger Thyroid Hormone Signaling in the Brain ELife. May, 2023 | Pubmed ID: 37204837 Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4) International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36674439 Different Hypothalamic Mechanisms Control Decreased Circulating Thyroid Hormone Levels in Infection and Fasting-Induced Non-Thyroidal Illness Syndrome in Male Thyroid Hormone Action Indicator Mice Thyroid : Official Journal of the American Thyroid Association. Jan, 2023 | Pubmed ID: 36322711 Tetrabromobisphenol A and Diclazuril Evoke Tissue-Specific Changes of Thyroid Hormone Signaling in Male Thyroid Hormone Action Indicator Mice International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36499108 Origin of Thyrotropin-releasing Hormone Neurons That Innervate the Tuberomammillary Nuclei Brain Structure & Function. Sep, 2022 | Pubmed ID: 35934753 Triiodothyronine (T3) Promotes Brown Fat Hyperplasia Via Thyroid Hormone Receptor α Mediated Adipocyte Progenitor Cell Proliferation Nature Communications. Jun, 2022 | Pubmed ID: 35697700 Tanycyte Specific Ablation of Diacylglycerol Lipase Alpha Stimulates the Hypothalamic-pituitary-thyroid Axis by Decreasing the Endocannabinoid Mediated Inhibition of TRH Release Journal of Neuroendocrinology. Jan, 2022 | Pubmed ID: 34970803 Expression of Glucagon-like Peptide 1 Receptor in Neuropeptide Y Neurons of the Arcuate Nucleus in Mice Brain Structure & Function. Jan, 2022 | Pubmed ID: 34596755 Distribution and Ultrastructural Localization of the Glucagon-like Peptide-1 Receptor (GLP-1R) in the Rat Brain Brain Structure & Function. Jan, 2021 | Pubmed ID: 33341919 A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release Via the Endocannabinoid System IScience. Mar, 2020 | Pubmed ID: 32143135 Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs Thyroid : Official Journal of the American Thyroid Association. Dec, 2019 | Pubmed ID: 31659941 Paradigms of Dynamic Control of Thyroid Hormone Signaling Endocrine Reviews. Aug, 2019 | Pubmed ID: 31033998 Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis Alcoholism, Clinical and Experimental Research. Jul, 2019 | Pubmed ID: 30908637 Type 2 Deiodinase Polymorphism Causes ER Stress and Hypothyroidism in the Brain The Journal of Clinical Investigation. Jan, 2019 | Pubmed ID: 30352046 The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia Cell Reports. Jan, 2018 | Pubmed ID: 29320745 A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action Endocrinology. Feb, 2018 | Pubmed ID: 29253128 Transient Hypothyroidism Favors Oligodendrocyte Generation Providing Functional Remyelination in the Adult Mouse Brain ELife. Sep, 2017 | Pubmed ID: 28875931 A Unique Haplotype of RCCX Copy Number Variation: from the Clinics of Congenital Adrenal Hyperplasia to Evolutionary Genetics European Journal of Human Genetics : EJHG. Jun, 2017 | Pubmed ID: 28401898 Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function Thyroid : Official Journal of the American Thyroid Association. Apr, 2017 | Pubmed ID: 27967605 Variable Proopiomelanocortin Expression in Tanycytes of the Adult Rat Hypothalamus and Pituitary Stalk The Journal of Comparative Neurology. Feb, 2017 | Pubmed ID: 27503597 Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice Endocrinology. Sep, 2016 | Pubmed ID: 27501182 Thyroid Hormone Activation by Type 2 Deiodinase Mediates Exercise-induced Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Expression in Skeletal Muscle The Journal of Physiology. Sep, 2016 | Pubmed ID: 27302464 Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function Cell Metabolism. May, 2016 | Pubmed ID: 27133129 Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis Via Type 2 Deiodinase in Male Mice Endocrinology. Jun, 2016 | Pubmed ID: 27046436 Different Types of Luciferase Reporters Show Distinct Susceptibility to T3-Evoked Downregulation Thyroid : Official Journal of the American Thyroid Association. Jan, 2016 | Pubmed ID: 26629840 Perinatal Deiodinase 2 Expression in Hepatocytes Defines Epigenetic Susceptibility to Liver Steatosis and Obesity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26508642 Scope and Limitations of Iodothyronine Deiodinases in Hypothyroidism Nature Reviews. Endocrinology. Nov, 2015 | Pubmed ID: 26416219 Endotoxin-induced Inflammation Down-regulates L-type Amino Acid Transporter 1 (LAT1) Expression at the Blood-brain Barrier of Male Rats and Mice Fluids and Barriers of the CNS. Sep, 2015 | Pubmed ID: 26337286 Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes Endocrinology. Oct, 2015 | Pubmed ID: 26214036 Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-brain Barrier of Male Rodents Endocrinology. Apr, 2015 | Pubmed ID: 25594699 Prevalent Polymorphism in Thyroid Hormone-activating Enzyme Leaves a Genetic Fingerprint That Underlies Associated Clinical Syndromes The Journal of Clinical Endocrinology and Metabolism. Mar, 2015 | Pubmed ID: 25569702 Differences in Hypothalamic Type 2 Deiodinase Ubiquitination Explain Localized Sensitivity to Thyroxine The Journal of Clinical Investigation. Feb, 2015 | Pubmed ID: 25555216 Tissue-specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse Diabetes. May, 2014 | Pubmed ID: 24487027 American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models Thyroid : Official Journal of the American Thyroid Association. Jan, 2014 | Pubmed ID: 24001133 The Type II Deiodinase is Retrotranslocated to the Cytoplasm and Proteasomes Via P97/Atx3 Complex Molecular Endocrinology (Baltimore, Md.). Dec, 2013 | Pubmed ID: 24196352 Coordination of Hypothalamic and Pituitary T3 Production Regulates TSH Expression The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23524969 Neuronal Hypoxia Induces Hsp40-mediated Nuclear Import of Type 3 Deiodinase As an Adaptive Mechanism to Reduce Cellular Metabolism The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2012 | Pubmed ID: 22723689 A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons PloS One. 2012 | Pubmed ID: 22719854 Endoplasmic Reticulum Stress Decreases Intracellular Thyroid Hormone Activation Via an EIF2a-mediated Decrease in Type 2 Deiodinase Synthesis Molecular Endocrinology (Baltimore, Md.). Dec, 2011 | Pubmed ID: 22053000 Thyroid Hormone and the Neuroglia: Both Source and Target Journal of Thyroid Research. 2011 | Pubmed ID: 21876836 KISS1R Intracellular Trafficking and Degradation: Effect of the Arg386Pro Disease-associated Mutation Endocrinology. Apr, 2011 | Pubmed ID: 21285314 Paracrine Signaling by Glial Cell-derived Triiodothyronine Activates Neuronal Gene Expression in the Rodent Brain and Human Cells The Journal of Clinical Investigation. Jun, 2010 | Pubmed ID: 20458138 Regulation of Thyroid Hormone Activation Via the Liver X-receptor/retinoid X-receptor Pathway The Journal of Endocrinology. May, 2010 | Pubmed ID: 20176747 Knockdown of the Type 3 Iodothyronine Deiodinase (D3) Interacting Protein Peroxiredoxin 3 Decreases D3-mediated Deiodination in Intact Cells Endocrinology. Nov, 2009 | Pubmed ID: 19819956 The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase Molecular and Cellular Biology. Oct, 2009 | Pubmed ID: 19651899 Cellular and Molecular Basis of Deiodinase-regulated Thyroid Hormone Signaling Endocrine Reviews. Dec, 2008 | Pubmed ID: 18815314 Lasting Changes in Social Behavior and Amygdala Function Following Traumatic Experience Induced by a Single Series of Foot-shocks Psychoneuroendocrinology. Oct, 2008 | Pubmed ID: 18656313 The Thyroid Hormone-inactivating Deiodinase Functions As a Homodimer Molecular Endocrinology (Baltimore, Md.). Jun, 2008 | Pubmed ID: 18356288 Expression Patterns of WSB-1 and USP-33 Underlie Cell-specific Posttranslational Control of Type 2 Deiodinase in the Rat Brain Endocrinology. Oct, 2007 | Pubmed ID: 17628004 Ubiquitination-induced Conformational Change Within the Deiodinase Dimer is a Switch Regulating Enzyme Activity Molecular and Cellular Biology. Jul, 2007 | Pubmed ID: 17452445 Metabolic Instability of Type 2 Deiodinase is Transferable to Stable Proteins Independently of Subcellular Localization The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16928685 Characterization of the Nuclear Factor-kappa B Responsiveness of the Human Dio2 Gene Endocrinology. Sep, 2006 | Pubmed ID: 16728495 Pretranslational Regulation of Type 2 Deiodinase Thyroid : Official Journal of the American Thyroid Association. Aug, 2005 | Pubmed ID: 16131328 The Hedgehog-inducible Ubiquitin Ligase Subunit WSB-1 Modulates Thyroid Hormone Activation and PTHrP Secretion in the Developing Growth Plate Nature Cell Biology. Jul, 2005 | Pubmed ID: 15965468 Ontogenic Redistribution of Type 2 Deiodinase Messenger Ribonucleic Acid in the Brain of Chicken Endocrinology. Aug, 2004 | Pubmed ID: 15087435 Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome Endocrinology. Apr, 2004 | Pubmed ID: 14684601 Deubiquitination of Type 2 Iodothyronine Deiodinase by Von Hippel-Lindau Protein-interacting Deubiquitinating Enzymes Regulates Thyroid Hormone Activation The Journal of Clinical Investigation. Jul, 2003 | Pubmed ID: 12865408 The MRNA Structure Has Potent Regulatory Effects on Type 2 Iodothyronine Deiodinase Expression Molecular Endocrinology (Baltimore, Md.). Jul, 2002 | Pubmed ID: 12089359 Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 신경과학
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 신경과학