Frank Maldarelli The virology Core at the HIV Drug Resistance Program NCI-Frederick Biography Publications Institution JoVE Articles Frank Maldarelli has not added a biography. If you are Frank Maldarelli and would like to personalize this page please email our Author Liaison for assistance. Publications Short-course Raltegravir Intensification Does Not Increase 2 Long Terminal Repeat Episomal HIV-1 DNA in Patients on Effective Antiretroviral Therapy Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2012 | Pubmed ID: 22016501 Short-course Combivir After Single-dose Nevirapine Reduces but Does Not Eliminate the Emergence of Nevirapine Resistance in Women Antiviral Therapy. Nov, 2011 | Pubmed ID: 22293443 Clinical Management of HIV Drug Resistance Viruses. Apr, 2011 | Pubmed ID: 21994737 Genotypic Resistance at Viral Rebound Among Patients Who Received Lopinavir/ritonavir-based or Efavirenz-based First Antiretroviral Therapy in South Africa Journal of Acquired Immune Deficiency Syndromes (1999). Nov, 2011 | Pubmed ID: 21694608 Majority of CD4+ T Cells from Peripheral Blood of HIV-1-infected Individuals Contain Only One HIV DNA Molecule Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21690402 Transmitted Raltegravir Resistance in an HIV-1 CRF_AG-infected Patient Antiviral Therapy. 2011 | Pubmed ID: 21447876 Estimate of Effective Recombination Rate and Average Selection Coefficient for HIV in Chronic Infection Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21436045 High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial The Journal of Infectious Diseases. Mar, 2011 | Pubmed ID: 21325137 CD4 and CD8 T Cell Immune Activation During Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2011 | Pubmed ID: 21257970 Targeting Viral Reservoirs: Ability of Antiretroviral Therapy to Stop Viral Replication Current Opinion in HIV and AIDS. Jan, 2011 | Pubmed ID: 21228755 Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques Despite Antiretroviral Therapy Journal of Virology. Jan, 2011 | Pubmed ID: 21084490 Characterization of the Meiosis-specific Recombinase Dmc1 of Pneumocystis The Journal of Infectious Diseases. Dec, 2010 | Pubmed ID: 21050123 XMRV: a New Virus in Prostate Cancer? Cancer Research. Dec, 2010 | Pubmed ID: 20966126 Current Status of Xenotropic Murine Leukemia Virus-related Retrovirus in Chronic Fatigue Syndrome and Prostate Cancer: Reach for a Scorecard, Not a Prescription Pad The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20936981 HIV-1 Continues to Replicate and Evolve in Patients with Natural Control of HIV Infection Journal of Virology. Dec, 2010 | Pubmed ID: 20926564 Patterns of Human Immunodeficiency Virus Type 1 Recombination Ex Vivo Provide Evidence for Coadaptation of Distant Sites, Resulting in Purifying Selection for Intersubtype Recombinants During Replication Journal of Virology. Aug, 2010 | Pubmed ID: 20504919 Comparison of Standard PCR/cloning to Single Genome Sequencing for Analysis of HIV-1 Populations Journal of Virological Methods. Sep, 2010 | Pubmed ID: 20451557 Optimization of Allele-specific PCR Using Patient-specific HIV Consensus Sequences for Primer Design Journal of Virological Methods. Mar, 2010 | Pubmed ID: 19948190 RT-SHIV Subpopulation Dynamics in Infected Macaques During Anti-HIV Therapy Retrovirology. 2009 | Pubmed ID: 19889213 Subtype-specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3'-azido-3'-deoxythymidine Journal of Virology. Sep, 2009 | Pubmed ID: 19553318 Evaluation of the Pathogenesis of Decreasing CD4(+) T Cell Counts in Human Immunodeficiency Virus Type 1-infected Patients Receiving Successfully Suppressive Antiretroviral Therapy The Journal of Infectious Diseases. Jun, 2009 | Pubmed ID: 19432547 Regimen Simplification to Atazanavir-ritonavir Alone As Maintenance Antiretroviral Therapy: Final 48-week Clinical and Virologic Outcomes The Journal of Infectious Diseases. Mar, 2009 | Pubmed ID: 19191590 Inferiority of IL-2 Alone Versus IL-2 with HAART in Maintaining CD4 T Cell Counts During HAART Interruption: a Randomized Controlled Trial AIDS (London, England). Jan, 2009 | Pubmed ID: 19098490 Lytic Granule Loading of CD8+ T Cells is Required for HIV-infected Cell Elimination Associated with Immune Control Immunity. Dec, 2008 | Pubmed ID: 19062316 Iatrogenic Cushing Syndrome After Epidural Triamcinolone Injections in an HIV Type 1-infected Patient Receiving Therapy with Ritonavir-lopinavir Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2008 | Pubmed ID: 18991509 Efavirenz Induces CYP2B6-mediated Hydroxylation of Bupropion in Healthy Subjects Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2008 | Pubmed ID: 18989234 Variation in the Major Surface Glycoprotein Genes in Pneumocystis Jirovecii The Journal of Infectious Diseases. Sep, 2008 | Pubmed ID: 18627244 Low-level Viremia Persists for at Least 7 Years in Patients on Suppressive Antiretroviral Therapy Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18332425 Frequent Polymorphism at Drug Resistance Sites in HIV-1 Protease and Reverse Transcriptase AIDS (London, England). Feb, 2008 | Pubmed ID: 18301062 Suppression of Viremia and Evolution of Human Immunodeficiency Virus Type 1 Drug Resistance in a Macaque Model for Antiretroviral Therapy Journal of Virology. Nov, 2007 | Pubmed ID: 17855539 ART Suppresses Plasma HIV-1 RNA to a Stable Set Point Predicted by Pretherapy Viremia PLoS Pathogens. Apr, 2007 | Pubmed ID: 17411338 Enfuvirtide Antiviral Activity Despite Rebound Viremia and Resistance Mutations: Fitness Tampering or a Case of Persistent Braking on Entering? The Journal of Infectious Diseases. Feb, 2007 | Pubmed ID: 17205468 Mutations in the Connection Domain of HIV-1 Reverse Transcriptase Increase 3'-azido-3'-deoxythymidine Resistance Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17179211 Tenofovir Disoproxil Fumarate and an Optimized Background Regimen of Antiretroviral Agents As Salvage Therapy: Impact on Bone Mineral Density in HIV-infected Children Pediatrics. Sep, 2006 | Pubmed ID: 16923923 Consistent Effects of TSG101 Genetic Variability on Multiple Outcomes of Exposure to Human Immunodeficiency Virus Type 1 Journal of Virology. Jul, 2006 | Pubmed ID: 16809281 Selection and Persistence of Non-nucleoside Reverse Transcriptase Inhibitor-resistant HIV-1 in Patients Starting and Stopping Non-nucleoside Therapy AIDS (London, England). Mar, 2006 | Pubmed ID: 16514300 Tenofovir Disoproxil Fumarate and an Optimized Background Regimen of Antiretroviral Agents As Salvage Therapy for Pediatric HIV Infection Pediatrics. Dec, 2005 | Pubmed ID: 16291735 Pravastatin Does Not Have a Consistent Antiviral Effect in Chronically HIV-infected Individuals on Antiretroviral Therapy AIDS (London, England). Jul, 2005 | Pubmed ID: 15958846 Mechanisms of Nonrandom Human Immunodeficiency Virus Type 1 Infection and Double Infection: Preference in Virus Entry is Important but is Not the Sole Factor Journal of Virology. Apr, 2005 | Pubmed ID: 15767415 Mechanism for Nucleoside Analog-mediated Abrogation of HIV-1 Replication: Balance Between RNase H Activity and Nucleotide Excision Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15684061 Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-experienced Patients Are Missed by Standard Genotype Analysis Journal of Clinical Microbiology. Jan, 2005 | Pubmed ID: 15635002 Prion Diseases: Update on Mad Cow Disease, Variant Creutzfeldt-Jakob Disease, and the Transmissible Spongiform Encephalopathies Current Infectious Disease Reports. Aug, 2004 | Pubmed ID: 15265460 A Proof-of-concept Study of Short-cycle Intermittent Antiretroviral Therapy with a Once-daily Regimen of Didanosine, Lamivudine, and Efavirenz for the Treatment of Chronic HIV Infection The Journal of Infectious Diseases. Jun, 2004 | Pubmed ID: 15143462 Changes in Hepatitis C Viral Response After Initiation of Highly Active Antiretroviral Therapy and Control of HIV Viremia in Chronically Co-infected Individuals HIV Clinical Trials. Jan-Feb, 2004 | Pubmed ID: 15002084 Nonrandom HIV-1 Infection and Double Infection Via Direct and Cell-mediated Pathways Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14707263 New Real-time Reverse Transcriptase-initiated PCR Assay with Single-copy Sensitivity for Human Immunodeficiency Virus Type 1 RNA in Plasma Journal of Clinical Microbiology. Oct, 2003 | Pubmed ID: 14532178 Innate Immunity in Human Immunodeficiency Virus Infection: Effect of Viremia on Natural Killer Cell Function The Journal of Infectious Diseases. Apr, 2003 | Pubmed ID: 12660917 HIV-1 Fitness and Replication Capacity: What Are They and Can They Help in Patient Management? Current Infectious Disease Reports. Feb, 2003 | Pubmed ID: 12525294 Amplifying और मानक नैदानिक Assays द्वारा जांच की सीमा से नीचे वायरल लोड के साथ एचआईवी संक्रमित व्यक्तियों में एचआईवी -1 शाही सेना बढ़ाता Helene Mens1, Mary Kearney1, Ann Wiegand1, Jonathan Spindler1, Frank Maldarelli1, John W. Mellors2, John M. Coffin3 1The virology Core at the HIV Drug Resistance Program, NCI-Frederick, 2Division of Infectious Diseases, University of Pittsburgh, 3Department of Molecular Biology and Microbiology, Tuffts University JoVE 2960 면역학 및 감염병학
Amplifying और मानक नैदानिक Assays द्वारा जांच की सीमा से नीचे वायरल लोड के साथ एचआईवी संक्रमित व्यक्तियों में एचआईवी -1 शाही सेना बढ़ाता Helene Mens1, Mary Kearney1, Ann Wiegand1, Jonathan Spindler1, Frank Maldarelli1, John W. Mellors2, John M. Coffin3 1The virology Core at the HIV Drug Resistance Program, NCI-Frederick, 2Division of Infectious Diseases, University of Pittsburgh, 3Department of Molecular Biology and Microbiology, Tuffts University JoVE 2960 면역학 및 감염병학