Hu Chen Mechanobiology Institute National University of Singapore Biography Publications Institution JoVE Articles Hu Chen has not added a biography. If you are Hu Chen and would like to personalize this page please email our Author Liaison for assistance. Publications The Effect of CCR5Δ32 on the Risk of Grade 3-4 Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis Clinical Transplantation. Sep, 2017 | Pubmed ID: 28862353 Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) As a Potent ALK/EGFR Dual Kinase Inhibitor Capable of Overcoming a Variety of ALK/EGFR Associated Drug Resistant Mutants in NSCLC European Journal of Medicinal Chemistry. Aug, 2017 | Pubmed ID: 28850922 All-trans Retinoic Acid Induces Autophagic Degradation of Ubiquitin-like Modifier Activating Enzyme 3 in Acute Promyelocytic Leukemia Cells Leukemia & Lymphoma. Aug, 2017 | Pubmed ID: 28849722 SIRT1 Functions As a Negative Regulator of Eukaryotic Poly(A)RNA Transport Current Biology : CB. Aug, 2017 | Pubmed ID: 28756945 Immediate Implant Placement into Posterior Sockets with or Without Buccal Bone Dehiscence Defects: A Retrospective Cohort Study Journal of Dentistry. Jul, 2017 | Pubmed ID: 28739320 Dithiopheneindenofluorene (TIF) Semiconducting Polymers with Very High Mobility in Field-Effect Transistors Advanced Materials (Deerfield Beach, Fla.). Jul, 2017 | Pubmed ID: 28731227 Transcriptome Landscape of Porcine Intramuscular Adipocytes During Differentiation Journal of Agricultural and Food Chemistry. Aug, 2017 | Pubmed ID: 28673084 Microbial Eukaryote Diversity and Activity in the Water Column of the South China Sea Based on DNA and RNA High Throughput Sequencing Frontiers in Microbiology. 2017 | Pubmed ID: 28659910 Socioeconomic Factors Affect the Selection of Proton Radiation Therapy for Children Cancer. Jun, 2017 | Pubmed ID: 28654202 Risk Factors for Graft-Versus-Host Disease After Transplantation of Hematopoietic Stem Cells from Unrelated Donors in the China Marrow Donor Program Annals of Transplantation. Jun, 2017 | Pubmed ID: 28652564 Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive-Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937 Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Jun, 2017 | Pubmed ID: 28648948 Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839 Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Sep, 2017 | Pubmed ID: 28629896 Structure-activity Relationship Investigation for Benzonaphthyridinone Derivatives As Novel Potent Bruton's Tyrosine Kinase (BTK) Irreversible Inhibitors European Journal of Medicinal Chemistry. Sep, 2017 | Pubmed ID: 28628824 Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN) IEEE Transactions on Medical Imaging. Jun, 2017 | Pubmed ID: 28622671 Prenatal Chromium Exposure and Risk of Preterm Birth: a Cohort Study in Hubei, China Scientific Reports. Jun, 2017 | Pubmed ID: 28596517 Laparoscopic Versus Open Distal Pancreatectomy for Pancreatic Ductal Adenocarcinoma: a Single-center Experience Journal of Zhejiang University. Science. B. Jun, 2017 | Pubmed ID: 28585429 Dexmedetomidine Alleviates Lipopolysaccharide-induced Lung Injury in Wistar Rats Oncotarget. Jul, 2017 | Pubmed ID: 28574842 AlCl3 Catalyzed Coupling of N-benzylic Sulfonamides with 2-substituted Cyanoacetates Through Carbon-nitrogen Bond Cleavage Organic & Biomolecular Chemistry. Jun, 2017 | Pubmed ID: 28561129 Identification of Long Non-coding RNA P34822 As a Potential Plasma Biomarker for the Diagnosis of Hepatocellular Carcinoma Science China. Life Sciences. Sep, 2017 | Pubmed ID: 28547580 Immunomodulatory Function of Whole Human Umbilical Cord Derived Mesenchymal Stem Cells Molecular Immunology. Jul, 2017 | Pubmed ID: 28531813 CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2017 | Pubmed ID: 28527722 Footprints of Domestication Revealed by RAD-tag Resequencing in Loquat: SNP Data Reveals a Non-significant Domestication Bottleneck and a Single Domestication Event BMC Genomics. May, 2017 | Pubmed ID: 28477616 ΔNp63α is a Common Inhibitory Target in Oncogenic PI3K/Ras/Her2-induced Cell Motility and Tumor Metastasis Proceedings of the National Academy of Sciences of the United States of America. May, 2017 | Pubmed ID: 28468801 [Establishment of Mouse Stably Knockout of MYSM1 in MSC Cell Line C3H10T1/2 and Its Effect on the Immune Regulation in Vitro] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Apr, 2017 | Pubmed ID: 28446309 Erratum To: Transposon Insertion Resulted in the Silencing of Wx-B1n in Chinese Wheat Landraces TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik. Jun, 2017 | Pubmed ID: 28434026 An Expedient Total Synthesis of Triciribine Molecules (Basel, Switzerland). Apr, 2017 | Pubmed ID: 28420174 Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells Stem Cells and Development. Jun, 2017 | Pubmed ID: 28418782 Systematic Characterization of A-to-I RNA Editing Hotspots in MicroRNAs Across Human Cancers Genome Research. Jul, 2017 | Pubmed ID: 28411194 Identification of a Novel Functional JAK1 S646P Mutation in Acute Lymphoblastic Leukemia Oncotarget. May, 2017 | Pubmed ID: 28410228 Discovery and Characterization of a Novel Irreversible EGFR Mutants Selective and Potent Kinase Inhibitor CHMFL-EGFR-26 with a Distinct Binding Mode Oncotarget. Mar, 2017 | Pubmed ID: 28407693 The Efficacy of Tocilizumab for the Treatment of Chinese Takayasu's Arteritis Clinical and Experimental Rheumatology. Mar-Apr, 2017 | Pubmed ID: 28406764 Elasticity of the Transition State Leading to an Unexpected Mechanical Stabilization of Titin Immunoglobulin Domains Angewandte Chemie (International Ed. in English). May, 2017 | Pubmed ID: 28394039 Neoantimycins A and B, Two Unusual Benzamido Nine-Membered Dilactones from Marine-Derived Streptomyces Antibioticus H12-15 Molecules (Basel, Switzerland). Mar, 2017 | Pubmed ID: 28358337 Irreversible Inhibition of BTK Kinase by a Novel Highly Selective Inhibitor CHMFL-BTK-11 Suppresses Inflammatory Response in Rheumatoid Arthritis Model Scientific Reports. Mar, 2017 | Pubmed ID: 28352114 A Phase 1/2 Trial of a Combination of Paclitaxel and Trastuzumab With Daily Irradiation or Paclitaxel Alone With Daily Irradiation After Transurethral Surgery for Noncystectomy Candidates With Muscle-Invasive Bladder Cancer (Trial NRG Oncology RTOG 0524) International Journal of Radiation Oncology, Biology, Physics. Apr, 2017 | Pubmed ID: 28333021 Transposon Insertion Resulted in the Silencing of Wx-B1n in Chinese Wheat Landraces TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik. Jun, 2017 | Pubmed ID: 28314934 Dual-Physical Cross-Linked Tough and Photoluminescent Hydrogels with Good Biocompatibility and Antibacterial Activity Macromolecular Rapid Communications. May, 2017 | Pubmed ID: 28295772 Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) As a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode Journal of Medicinal Chemistry. Apr, 2017 | Pubmed ID: 28282122 Salinomycin Repressed the Epithelial-mesenchymal Transition of Epithelial Ovarian Cancer Cells Via Downregulating Wnt/β-catenin Pathway OncoTargets and Therapy. 2017 | Pubmed ID: 28280366 Low-dose CT Via Convolutional Neural Network Biomedical Optics Express. Feb, 2017 | Pubmed ID: 28270976 The Antimicrobial Activity of Nanoparticles: Present Situation and Prospects for the Future International Journal of Nanomedicine. 2017 | Pubmed ID: 28243086 Pen-2 and Presenilin Are Sufficient to Catalyze Notch Processing Journal of Alzheimer's Disease : JAD. 2017 | Pubmed ID: 28234257 Long-term Outcomes With Planned Multistage Reduced Dose Repeat Stereotactic Radiosurgery for Treatment of Inoperable High-Grade Arteriovenous Malformations: An Observational Retrospective Cohort Study Neurosurgery. Jul, 2017 | Pubmed ID: 28201783 Lurasidone Versus Treatment As Usual for Cognitive Impairment in Euthymic Patients with Bipolar I Disorder: a Randomised, Open-label, Pilot Study The Lancet. Psychiatry. Mar, 2017 | Pubmed ID: 28185899 Silencing Myotubularin Related Protein 7 Enhances Proliferation and Early Differentiation of C2C12 Myoblast Biochemical and Biophysical Research Communications. Mar, 2017 | Pubmed ID: 28153733 Palmdelphin Promotes Myoblast Differentiation and Muscle Regeneration Scientific Reports. Feb, 2017 | Pubmed ID: 28148961 Highly Active Three-Dimensional NiFe/Cu2 O Nanowires/Cu Foam Electrode for Water Oxidation ChemSusChem. Apr, 2017 | Pubmed ID: 28101949 Reply to D. Ball Et Al Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2017 | Pubmed ID: 28068179 Water Oxidation Catalyzed by a Charge-neutral Mononuclear Ruthenium(iii) Complex Dalton Transactions (Cambridge, England : 2003). Jan, 2017 | Pubmed ID: 28067397 Screening, Purification, and Characterization of a Novel Organic Solvent-tolerant Esterase, Lip2, from Monascus Purpureus Strain M7 Extremophiles : Life Under Extreme Conditions. Mar, 2017 | Pubmed ID: 28062919 Arabidopsis CBF3 and DELLAs Positively Regulate Each Other in Response to Low Temperature Scientific Reports. Jan, 2017 | Pubmed ID: 28051152 Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2017 | Pubmed ID: 28034064 Early Detection of Trichinella Spiralis DNA in the Feces of Experimentally Infected Mice by Using PCR Acta Tropica. Feb, 2017 | Pubmed ID: 27983972 Discovery of 4-Methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((1-nicotinoylpiperidin-4-yl)oxy)benzamide (CHMFL-ABL/KIT-155) As a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding Journal of Medicinal Chemistry. Jan, 2017 | Pubmed ID: 27966954 Treatment Design and Rationale for a Randomized Trial of Cisplatin and Etoposide Plus Thoracic Radiotherapy Followed by Nivolumab or Placebo for Locally Advanced Non-Small-Cell Lung Cancer (RTOG 3505) Clinical Lung Cancer. May, 2017 | Pubmed ID: 27923550 Trajectories of Body Mass Index Change in First Episode of Mania: 3-year Data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM) Journal of Affective Disorders. Jan, 2017 | Pubmed ID: 27794253 Prescribing Patterns of Psychotropic Medications and Clinical Features in Patients with Major Depressive Disorder with and Without Comorbid Dysthymia in China Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists. Mar, 2017 | Pubmed ID: 27759189 Anaplastic Lymphoma Kinase Regulates Binge-like Drinking and Dopamine Receptor Sensitivity in the Ventral Tegmental Area Addiction Biology. May, 2017 | Pubmed ID: 26752591 Third-generation CD28/4-1BB Chimeric Antigen Receptor T Cells for Chemotherapy Relapsed or Refractory Acute Lymphoblastic Leukaemia: a Non-randomised, Open-label Phase I Trial Protocol BMJ Open. Dec, 2016 | Pubmed ID: 28039295 Tumor-Specific D-Dimer Concentration Ranges and Influencing Factors: A Cross-Sectional Study PloS One. 2016 | Pubmed ID: 27835633 Learning From Trials on Radiation Dose in Non-Small Cell Lung Cancer International Journal of Radiation Oncology, Biology, Physics. Nov, 2016 | Pubmed ID: 27788947 Meta-Analysis of Laparoscopic Versus Open Hepatectomy for Live Liver Donors PloS One. 2016 | Pubmed ID: 27788201 The Efficacy and Safety of Anti-PD-1/PD-L1 Antibodies for Treatment of Advanced or Refractory Cancers: a Meta-analysis Oncotarget. 11, 2016 | Pubmed ID: 27683031 HMGB2 Regulates Satellite-cell-mediated Skeletal Muscle Regeneration Through IGF2BP2 Journal of Cell Science. Nov, 2016 | Pubmed ID: 27672022 Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2016 | Pubmed ID: 27646951 Ibrutinib Targets Mutant-EGFR Kinase with a Distinct Binding Conformation Oncotarget. Oct, 2016 | Pubmed ID: 27626175 A Super Twin T-DNA Vector That Allows Independent Gene Expression During Agrobacterium-mediated Transformation Plasmid. Sep - Nov, 2016 | Pubmed ID: 27615011 Community-acquired Pneumonia and Survival of Critically Ill Acute Exacerbation of COPD Patients in Respiratory Intensive Care Units International Journal of Chronic Obstructive Pulmonary Disease. 2016 | Pubmed ID: 27563239 Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) As a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of CKIT Kinase Journal of Medicinal Chemistry. Sep, 2016 | Pubmed ID: 27545040 Broadly Tunable Mode-locked Ho:YAG Ceramic Laser Around 2.1 µm Optics Express. Aug, 2016 | Pubmed ID: 27505767 Evolutionary and Functional Analysis of Mulberry Type III Polyketide Synthases BMC Genomics. Aug, 2016 | Pubmed ID: 27487946 ATF4 Regulates SREBP1c Expression to Control Fatty Acids Synthesis in 3T3-L1 Adipocytes Differentiation Biochimica Et Biophysica Acta. 11, 2016 | Pubmed ID: 27452504 Synthesis and Cytotoxicity Evaluation of 4'-amino-4'-dehydroxyloleandrin Derivatives Fitoterapia. Sep, 2016 | Pubmed ID: 27431773 Base-Catalyzed Hydrophosphination of Azobenzenes with Diarylphosphine Oxides: A Precise Construction of N-N-P Unit The Journal of Organic Chemistry. Aug, 2016 | Pubmed ID: 27387595 Improved Synthesis and Growth of Graphene Oxide for Field Effect Transistor Biosensors Biomedical Microdevices. Aug, 2016 | Pubmed ID: 27379845 The Psychometric Properties of the Quick Inventory of Depressive Symptomatology-Self-Report (QIDS-SR) and the Patient Health Questionnaire-9 (PHQ-9) in Depressed Inpatients in China Psychiatry Research. Sep, 2016 | Pubmed ID: 27376668 Cathepsin S Activity Controls Injury-Related Vascular Repair in Mice Via the TLR2-Mediated P38MAPK and PI3K-Akt/p-HDAC6 Signaling Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2016 | Pubmed ID: 27365406 Discovery and Characterization of a Novel Potent Type II Native and Mutant BCR-ABL Inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) Oncotarget. Jul, 2016 | Pubmed ID: 27322145 Elevated Periostin in Serum and Peritoneal Washing Fluids As Potential Biomarkers for Endometriosis Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology. Nov, 2016 | Pubmed ID: 27251862 MiR-709 Modulates LPS-induced Inflammatory Response Through Targeting GSK-3β International Immunopharmacology. Jul, 2016 | Pubmed ID: 27232654 Clinical Characteristics of Patients with Diabetic Nephropathy on Maintenance Hemodialysis: A Multicenter Cross-sectional Survey in Anhui Province, Eastern China Chinese Medical Journal. Jun, 2016 | Pubmed ID: 27231165 Moderate and Strong Static Magnetic Fields Directly Affect EGFR Kinase Domain Orientation to Inhibit Cancer Cell Proliferation Oncotarget. Jul, 2016 | Pubmed ID: 27223425 Comprehensive Characterization of Molecular Differences in Cancer Between Male and Female Patients Cancer Cell. 05, 2016 | Pubmed ID: 27165743 Ergosterols from the Culture Broth of Marine Streptomyces Anandii H41-59 Marine Drugs. May, 2016 | Pubmed ID: 27153073 [Application of Cytotoxic T-Lymphocytes for the Treatment of Cytomegalovirus Infection in Hematopoietic Stem Cell Transplantation] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Apr, 2016 | Pubmed ID: 27151040 [Analysis of Risk Factors for Cytomegalovirus Infection After Allogeneic Hematopoietic Stem Cell Transplantation] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Apr, 2016 | Pubmed ID: 27151028 [Treatment of Cranial-cervical Aneurysms with Stent-graft: 20 Cases Report with Short-term Follow-up] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. May, 2016 | Pubmed ID: 27143203 Adoptive Transfer of T Cells Transduced with a Chimeric Antigen Receptor to Treat Relapsed or Refractory Acute Leukemia: Efficacy and Feasibility of Immunotherapy Approaches Science China. Life Sciences. Jul, 2016 | Pubmed ID: 27142351 Corrigendum: Nonvolatile Modulation of Electronic Structure and Correlative Magnetism of L10-FePt Films Using Significant Strain Induced by Shape Memory Substrates Scientific Reports. Apr, 2016 | Pubmed ID: 27094438 Dual Inhibition of AKT/FLT3-ITD by A674563 Overcomes FLT3 Ligand-induced Drug Resistance in FLT3-ITD Positive AML Oncotarget. May, 2016 | Pubmed ID: 27074558 An Adsorption-release-biodegradation System for Simultaneous Biodegradation of Phenol and Ammonium in Phenol-rich Wastewater Bioresource Technology. Jul, 2016 | Pubmed ID: 27060247 Anti-Inflammatory and Antinociceptive Properties of Flavonoids from the Fruits of Black Mulberry (Morus Nigra L.) PloS One. 2016 | Pubmed ID: 27046026 Inhibiting ROS-STAT3-dependent Autophagy Enhanced Capsaicin-induced Apoptosis in Human Hepatocellular Carcinoma Cells Free Radical Research. Jul, 2016 | Pubmed ID: 27043357 Effect of MiR-26a-5p on the Wnt/Ca(2+) Pathway and Osteogenic Differentiation of Mouse Adipose-Derived Mesenchymal Stem Cells Calcified Tissue International. Aug, 2016 | Pubmed ID: 27040676 A Review on Electronic Bio-sensing Approaches Based on Non-antibody Recognition Elements The Analyst. Apr, 2016 | Pubmed ID: 27002177 Ubiquitin-specific Peptidase 10 (USP10) Deubiquitinates and Stabilizes MutS Homolog 2 (MSH2) to Regulate Cellular Sensitivity to DNA Damage The Journal of Biological Chemistry. May, 2016 | Pubmed ID: 26975374 Fe3 O4 Anisotropic Nanostructures in Hydrogels: Efficient Catalysts for the Rapid Removal of Organic Dyes from Wastewater Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jul, 2016 | Pubmed ID: 26955896 ITRAQ-based Quantitative Proteomic Analysis Reveals the Distinct Early Embryo Myofiber Type Characteristics Involved in Landrace and Miniature Pig BMC Genomics. Feb, 2016 | Pubmed ID: 26911206 Using "On/Off" (19)F NMR/Magnetic Resonance Imaging Signals to Sense Tyrosine Kinase/Phosphatase Activity in Vitro and in Cell Lysates Analytical Chemistry. Mar, 2016 | Pubmed ID: 26901415 Detection of Matrilysin Activity Using Polypeptide Functionalized Reduced Graphene Oxide Field-Effect Transistor Sensor Analytical Chemistry. Mar, 2016 | Pubmed ID: 26887256 Erratum. A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients with Stage I Peripheral Non-small Cell Lung Cancer: NRG Oncology RTOG 0915 (NCCTG N0927) International Journal of Radiation Oncology, Biology, Physics. Mar, 2016 | Pubmed ID: 26867895 Nonvolatile Modulation of Electronic Structure and Correlative Magnetism of L10-FePt Films Using Significant Strain Induced by Shape Memory Substrates Scientific Reports. Feb, 2016 | Pubmed ID: 26830325 Emodin Inhibits Epithelial to Mesenchymal Transition in Epithelial Ovarian Cancer Cells by Regulation of GSK-3β/β-catenin/ZEB1 Signaling Pathway Oncology Reports. Apr, 2016 | Pubmed ID: 26820690 Argirein Alleviates Stress-induced and Diabetic Hypogonadism in Rats Via Normalizing Testis Endothelin Receptor A and Connexin 43 Acta Pharmacologica Sinica. Feb, 2016 | Pubmed ID: 26775665 Application of FDM Three-dimensional Printing Technology in the Digital Manufacture of Custom Edentulous Mandible Trays Scientific Reports. Jan, 2016 | Pubmed ID: 26763620 Molecular Characterization of Melanin-concentrating Hormone (MCH) in Schizothorax Prenanti: Cloning, Tissue Distribution and Role in Food Intake Regulation Fish Physiology and Biochemistry. Jun, 2016 | Pubmed ID: 26690629 Quality of Life Analysis of a Radiation Dose-Escalation Study of Patients With Non-Small-Cell Lung Cancer: A Secondary Analysis of the Radiation Therapy Oncology Group 0617 Randomized Clinical Trial JAMA Oncology. Mar, 2016 | Pubmed ID: 26606200 Treatment of Psoriasis with Mesenchymal Stem Cells The American Journal of Medicine. Mar, 2016 | Pubmed ID: 26582058 Genomic and Molecular Mechanisms for Efficient Biodegradation of Aromatic Dye Journal of Hazardous Materials. Jan, 2016 | Pubmed ID: 26476316 Ya-fish (Schizothorax Prenanti) Spexin: Identification, Tissue Distribution and MRNA Expression Responses to Periprandial and Fasting Fish Physiology and Biochemistry. Feb, 2016 | Pubmed ID: 26311351 Nicastrin is Required for APP but Not Notch Processing, While Aph-1 is Dispensable for Processing of Both APP and Notch Journal of Neurochemistry. Dec, 2015 | Pubmed ID: 26717550 [Association of Obstructive Sleep Apnea Hypopnea Syndrome with Carotid Atherosclerosis and the Efficacy of Continuous Positive Airway Pressure Treatment] Zhonghua Yi Xue Za Zhi. Sep, 2015 | Pubmed ID: 26711980 [Cellular Immune Therapy for Epstein-Barr Virus Infection After Hematopoietic Stem Cell Transplantation] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Dec, 2015 | Pubmed ID: 26708907 MicroRNA-130b Promotes Cell Migration and Invasion by Targeting Peroxisome Proliferator-activated Receptor Gamma in Human Glioma Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Dec, 2015 | Pubmed ID: 26653558 Revisiting the Anomalous Bending Elasticity of Sharply Bent DNA Biophysical Journal. Dec, 2015 | Pubmed ID: 26636945 Association Between Polymorphisms of DRD2, COMT, DBH, and MAO-A Genes and Migraine Susceptibility: A Meta-Analysis Medicine. Nov, 2015 | Pubmed ID: 26632697 Discovery of (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-(dimethylamino)ethanone (CHMFL-FLT3-122) As a Potent and Orally Available FLT3 Kinase Inhibitor for FLT3-ITD Positive Acute Myeloid Leukemia Journal of Medicinal Chemistry. Dec, 2015 | Pubmed ID: 26630553 Quantitative Evaluation of Tissue Surface Adaption of CAD-Designed and 3D Printed Wax Pattern of Maxillary Complete Denture BioMed Research International. 2015 | Pubmed ID: 26583108 Not All the Number of Skeletal Muscle Fibers is Determined Prenatally BMC Developmental Biology. Nov, 2015 | Pubmed ID: 26559169 A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer: NRG Oncology RTOG 0915 (NCCTG N0927) International Journal of Radiation Oncology, Biology, Physics. Nov, 2015 | Pubmed ID: 26530743 Outcome of Myeloablative Allogeneic Peripheral Blood Hematopoietic Stem Cell Transplantation for Refractory/relapsed AML Patients in NR Status Leukemia Research. Dec, 2015 | Pubmed ID: 26530539 Polyethyleneimine-Based Nanocarriers for Gene Delivery Current Pharmaceutical Design. 2015 | Pubmed ID: 26503146 Conductance Quantization in Resistive Random Access Memory Nanoscale Research Letters. Dec, 2015 | Pubmed ID: 26501832 [Therapeutic Effect of CY-fTBI and BMM Conditioning Regimen in the Process of Allo-HSCT Treating Ⅲ,Ⅳ Non-Hodgkin Lymphoma: 15 Years Analysis of Single-center] Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi. Oct, 2015 | Pubmed ID: 26477760 Hsp27 Acts As a Master Molecular Chaperone and Plays an Essential Role in Hepatocellular Carcinoma Progression Digestion. 2015 | Pubmed ID: 26381739 Efficiency of CD19 Chimeric Antigen Receptor-modified T Cells for Treatment of B Cell Malignancies in Phase I Clinical Trials: a Meta-analysis Oncotarget. Oct, 2015 | Pubmed ID: 26376680 Ibrutinib Selectively and Irreversibly Targets EGFR (L858R, Del19) Mutant but is Moderately Resistant to EGFR (T790M) Mutant NSCLC Cells Oncotarget. Oct, 2015 | Pubmed ID: 26375053 MicroRNA-203-mediated Posttranscriptional Deregulation of CPEB4 Contributes to Colorectal Cancer Progression Biochemical and Biophysical Research Communications. Oct, 2015 | Pubmed ID: 26361147 Repeated Binge Drinking Increases Perineuronal Nets in the Insular Cortex Alcoholism, Clinical and Experimental Research. Oct, 2015 | Pubmed ID: 26332441 Investigation and Analysis of Genetic Diversity of Diospyros Germplasms Using SCoT Molecular Markers in Guangxi PloS One. 2015 | Pubmed ID: 26317414 Appetite Regulation in Schizothorax Prenanti by Three CART Genes General and Comparative Endocrinology. Dec, 2015 | Pubmed ID: 26316039 Protective Effect of the ω-3 Polyunsaturated Fatty Acids on the Schistosomiasis Liver Fibrosis in Mice International Journal of Clinical and Experimental Medicine. 2015 | Pubmed ID: 26309610 Neurosubstrates and Mechanisms Underlying the Extinction of Associative Motor Memory Neurobiology of Learning and Memory. Dec, 2015 | Pubmed ID: 26209112 Ethanol Activates Midkine and Anaplastic Lymphoma Kinase Signaling in Neuroblastoma Cells and in the Brain Journal of Neurochemistry. Nov, 2015 | Pubmed ID: 26206265 YAG:Ce/(Gd,Y)AG:Ce Dual-layered Composite Structure Ceramic Phosphors Designed for Bright White Light-emitting Diodes with Various CCT Optics Express. Jul, 2015 | Pubmed ID: 26191881 Epidemiological Features of Viral Encephalitis in Cangzhou of China with Use of Multiplex RT-PCR for Five RNA Viruses Journal of Virological Methods. Sep, 2015 | Pubmed ID: 26118966 Triterpenoid Saponins from the Root Bark of Schima Superba and Their Cytotoxic Activity on B16 Melanoma Cell Line Carbohydrate Research. Sep, 2015 | Pubmed ID: 26117824 Importance of Local Control in Early-Stage Prostate Cancer: Outcomes of Patients With Positive Post-Radiation Therapy Biopsy Results Treated in RTOG 9408 International Journal of Radiation Oncology, Biology, Physics. Jul, 2015 | Pubmed ID: 26104939 Phase II Trial of Pre-irradiation and Concurrent Temozolomide in Patients with Newly Diagnosed Anaplastic Oligodendrogliomas and Mixed Anaplastic Oligoastrocytomas: Long Term Results of RTOG BR0131 Journal of Neuro-oncology. Sep, 2015 | Pubmed ID: 26088460 The Effects of Lactobacillus Acidophilus on the Intestinal Smooth Muscle Contraction Through PKC/MLCK/MLC Signaling Pathway in TBI Mouse Model PloS One. 2015 | Pubmed ID: 26030918 Cellular FLICE-like Inhibitory Protein (c-FLIP) and PS1-associated Protein (PSAP) Mediate Presenilin 1-induced γ-Secretase-dependent and -independent Apoptosis, Respectively The Journal of Biological Chemistry. Jul, 2015 | Pubmed ID: 26025363 New Cytotoxic 19-norbufadienolide and Bufogargarizin Isolated from Chan Su Fitoterapia. Jul, 2015 | Pubmed ID: 25987318 The Challenge of a "Functional Cure" for AIDS by Gene Modified HSCT Therapy Current Stem Cell Research & Therapy. 2015 | Pubmed ID: 25986619 Effects of Transcranial Direct Current Stimulation (tDCS) on Multiscale Complexity of Dual-task Postural Control in Older Adults Experimental Brain Research. Aug, 2015 | Pubmed ID: 25963755 MiR-154-5p Regulates Osteogenic Differentiation of Adipose-derived Mesenchymal Stem Cells Under Tensile Stress Through the Wnt/PCP Pathway by Targeting Wnt11 Bone. Sep, 2015 | Pubmed ID: 25959411 NaYF4:Yb,Er-MoS2: from Synthesis and Surface Ligand Stripping to Negative Infrared Photoresponse Chemical Communications (Cambridge, England). May, 2015 | Pubmed ID: 25941681 Association Between Epidermal Growth Factor Gene +61A/G Polymorphism and the Risk of Hepatocellular Carcinoma: a Meta-analysis Based on 16 Studies BMC Cancer. Apr, 2015 | Pubmed ID: 25927412 An Update of MiRNASNP Database for Better SNP Selection by GWAS Data, MiRNA Expression and Online Tools Database : the Journal of Biological Databases and Curation. 2015 | Pubmed ID: 25877638 Thermodynamics of Force-dependent Folding and Unfolding of Small Protein and Nucleic Acid Structures Integrative Biology : Quantitative Biosciences from Nano to Macro. Oct, 2015 | Pubmed ID: 25799983 Molecular Cloning, Expression Analysis, and Appetite Regulatory Effect of Peptide YY in Siberian Sturgeon (Acipenser Baerii) Gene. Jun, 2015 | Pubmed ID: 25791494 Dynamics of Equilibrium Folding and Unfolding Transitions of Titin Immunoglobulin Domain Under Constant Forces Journal of the American Chemical Society. Mar, 2015 | Pubmed ID: 25726700 Femtosecond Laser Ablation of Dentin and Enamel: Relationship Between Laser Fluence and Ablation Efficiency Journal of Biomedical Optics. Feb, 2015 | Pubmed ID: 25695161 Fibulin-5 is a Prognostic Marker That Contributes to Proliferation and Invasion of Human Glioma Cells Asian Pacific Journal of Cancer Prevention : APJCP. 2015 | Pubmed ID: 25684523 Phase 2 Study of Temozolomide-based Chemoradiation Therapy for High-risk Low-grade Gliomas: Preliminary Results of Radiation Therapy Oncology Group 0424 International Journal of Radiation Oncology, Biology, Physics. Mar, 2015 | Pubmed ID: 25680596 Imaging Findings and Histologic Appearances of Alveolar Soft Part Sarcoma in the Prostate: A Case Report and Review of the Literature Clinical Genitourinary Cancer. Aug, 2015 | Pubmed ID: 25604914 Standard-dose Versus High-dose Conformal Radiotherapy with Concurrent and Consolidation Carboplatin Plus Paclitaxel with or Without Cetuximab for Patients with Stage IIIA or IIIB Non-small-cell Lung Cancer (RTOG 0617): a Randomised, Two-by-two Factorial Phase 3 Study The Lancet. Oncology. Feb, 2015 | Pubmed ID: 25601342 Granulocyte Colony-stimulating Factor-primed Bone Marrow: an Excellent Stem-cell Source for Transplantation in Acute Myelocytic Leukemia and Chronic Myelocytic Leukemia Chinese Medical Journal. Jan, 2015 | Pubmed ID: 25563308 CEP2 Attenuates Myoblast Differentiation but Does Not Affect Proliferation International Journal of Biological Sciences. 2015 | Pubmed ID: 25552934 Reporter-encapsulated Liposomes on Graphene Field Effect Transistors for Signal Enhanced Detection of Physiological Enzymes Physical Chemistry Chemical Physics : PCCP. Feb, 2015 | Pubmed ID: 25531209 Impact of Biochemical Failure Classification on Clinical Outcome: a Secondary Analysis of Radiation Therapy Oncology Group 9202 and 9413 Cancer. Mar, 2015 | Pubmed ID: 25410885 Demographic and Clinical Differences Between Early- and Late-onset Major Depressions in Thirteen Psychiatric Institutions in China Journal of Affective Disorders. Jan, 2015 | Pubmed ID: 25265534 Oroxylin A Induces Autophagy in Human Malignant Glioma Cells Via the MTOR-STAT3-Notch Signaling Pathway Molecular Carcinogenesis. Nov, 2015 | Pubmed ID: 25213258 Doxorubicin Inhibits Proliferation of Osteosarcoma Cells Through Upregulation of the Notch Signaling Pathway Oncology Research. 2014 | Pubmed ID: 26351207 A Roughness Study of Ytterbium-Doped Potassium Yttrium Tungstate (YB: KYW) Thin-Disk Femtosecond Ablated Dentin Journal of Lasers in Medical Sciences. 2014 | Pubmed ID: 25606337 CCR7 Expressing Mesenchymal Stem Cells Potently Inhibit Graft-versus-host Disease by Spoiling the Fourth Supplemental Billingham's Tenet PloS One. 2014 | Pubmed ID: 25549354 Preparation and Characterisation of Poly P-phenylene-2,6-benzobisoxazole Fibre-reinforced Resin Matrix Composite for Endodontic Post Material: a Preliminary Study Journal of Dentistry. Dec, 2014 | Pubmed ID: 25446737 The Immunologic and Hematopoietic Profiles of Mesenchymal Stem Cells Derived from Different Sections of Human Umbilical Cord Acta Biochimica Et Biophysica Sinica. Dec, 2014 | Pubmed ID: 25377438 Interconversion Between Three Overstretched DNA Structures Journal of the American Chemical Society. Nov, 2014 | Pubmed ID: 25337990 Mechanical Force Antagonizes the Inhibitory Effects of RecX on RecA Filament Formation in Mycobacterium Tuberculosis Nucleic Acids Research. Oct, 2014 | Pubmed ID: 25294832 [Meilian Xiaoke Capsule Combined with Metformin for Protecting Islet Cells and Lowering Blood Glucose in Diabetic Rats] Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University. Aug, 2014 | Pubmed ID: 25263377 Baseline Theta Activities in Medial Prefrontal Cortex and Deep Cerebellar Nuclei Are Associated with the Extinction of Trace Conditioned Eyeblink Responses in Guinea Pigs Behavioural Brain Research. Dec, 2014 | Pubmed ID: 25200518 Molecular and Physiological Evidences for the Role in Appetite Regulation of Apelin and Its Receptor APJ in Ya-fish (Schizothorax Prenanti) Molecular and Cellular Endocrinology. Oct, 2014 | Pubmed ID: 25150624 Crystal Structure of Juvenile Hormone Epoxide Hydrolase from the Silkworm Bombyx Mori Proteins. Nov, 2014 | Pubmed ID: 25143157 [Dendritic Cells and Acute Myeloid Leukemia] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Aug, 2014 | Pubmed ID: 25130846 Single-mode Air-clad Liquid-core Waveguides on a Surface Energy Patterned Substrate Optics Letters. Aug, 2014 | Pubmed ID: 25121914 MiR-709 Inhibits 3T3-L1 Cell Differentiation by Targeting GSK3β of Wnt/β-catenin Signaling Cellular Signalling. Nov, 2014 | Pubmed ID: 25038456 HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSα Molecular Cell. Jul, 2014 | Pubmed ID: 24882211 Applications of TALENs and CRISPR/Cas9 in Human Cells and Their Potentials for Gene Therapy Molecular Biotechnology. Aug, 2014 | Pubmed ID: 24870618 Leptin and Cholecystokinin in Schizothorax Prenanti: Molecular Cloning, Tissue Expression, and MRNA Expression Responses to Periprandial Changes and Fasting General and Comparative Endocrinology. Aug, 2014 | Pubmed ID: 24852347 Synergetically Enhanced Near-infrared Photoresponse of Reduced Graphene Oxide by Upconversion and Gold Plasmon Small (Weinheim an Der Bergstrasse, Germany). Sep, 2014 | Pubmed ID: 24821086 Rate of False Conviction of Criminal Defendants Who Are Sentenced to Death Proceedings of the National Academy of Sciences of the United States of America. May, 2014 | Pubmed ID: 24778209 Cloning and Expression Analyses of the Anthocyanin Biosynthetic Genes in Mulberry Plants Molecular Genetics and Genomics : MGG. Oct, 2014 | Pubmed ID: 24748075 The Micropatterning of Layers of Colloidal Quantum Dots with Inorganic Ligands Using Selective Wet Etching Nanotechnology. May, 2014 | Pubmed ID: 24722007 Clinical Research of Genetically Modified Dendritic Cells in Combination with Cytokine-induced Killer Cell Treatment in Advanced Renal Cancer BMC Cancer. Apr, 2014 | Pubmed ID: 24720900 Mechanical Activation of Vinculin Binding to Talin Locks Talin in an Unfolded Conformation Scientific Reports. Apr, 2014 | Pubmed ID: 24714394 Attenuated A20 Expression of Acute Myeloid Leukemia-derived Dendritic Cells Increased the Anti-leukemia Immune Response of Autologous Cytolytic T Cells Leukemia Research. Jun, 2014 | Pubmed ID: 24713261 Evaluation of Mood Disorder Questionnaire (MDQ) in Patients with Mood Disorders: a Multicenter Trial Across China PloS One. 2014 | Pubmed ID: 24705393 Schizothorax Prenanti Corticotropin-releasing Hormone (CRH): Molecular Cloning, Tissue Expression, and the Function of Feeding Regulation Fish Physiology and Biochemistry. Oct, 2014 | Pubmed ID: 24696302 MicroRNA-145 Suppresses Hepatocellular Carcinoma by Targeting IRS1 and Its Downstream Akt Signaling Biochemical and Biophysical Research Communications. Apr, 2014 | Pubmed ID: 24690171 Molecular Characterization and Tissue Expression of Peptide YY in Schizothorax Prenanti: Effects of Periprandial Changes and Fasting on Expression in the Hypothalamus Regulatory Peptides. May, 2014 | Pubmed ID: 24681121 Activating Transcription Factor 4 Regulates Adipocyte Differentiation Via Altering the Coordinate Expression of CCATT/enhancer Binding Protein β and Peroxisome Proliferator-activated Receptor γ The FEBS Journal. May, 2014 | Pubmed ID: 24673832 Pulmonary Lymphangitic Carcinomatosis in Liver Carcinoma: a Rare Case Report and Literature Review World Journal of Surgical Oncology. Mar, 2014 | Pubmed ID: 24669948 [Distribution of Compact Bone Mesenchymal Stem Cells in Lung Tissue and Bone Marrow of Mouse] Zhongguo Shi Yan Xue Ye Xue Za Zhi. Feb, 2014 | Pubmed ID: 24598672 Predictive Nature of Prefrontal Theta Oscillation on the Performance of Trace Conditioned Eyeblink Responses in Guinea Pigs Behavioural Brain Research. May, 2014 | Pubmed ID: 24572215 Discovery of a Potent, Covalent BTK Inhibitor for B-Cell Lymphoma ACS Chemical Biology. May, 2014 | Pubmed ID: 24556163 A Highly Sensitive Immunosensor for Calmodulin Assay Based on Enhanced Biocatalyzed Precipitation Adopting a Dual-layered Enzyme Strategy Biosensors & Bioelectronics. Jun, 2014 | Pubmed ID: 24508817 CCR7 Guides Migration of Mesenchymal Stem Cell to Secondary Lymphoid Organs: a Novel Approach to Separate GvHD from GvL Effect Stem Cells (Dayton, Ohio). Jul, 2014 | Pubmed ID: 24496849 [Preparation of Recombinant Adenovirus Ad5/F35 Containing Human WT1 and Identification After Recombinant Adenovirus Infected Dendritic Cells] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Feb, 2014 | Pubmed ID: 24491051 Comparative Study of Nanosecond Electric Fields in Vitro and in Vivo on Hepatocellular Carcinoma Indicate Macrophage Infiltration Contribute to Tumor Ablation in Vivo PloS One. 2014 | Pubmed ID: 24475118 [Occurrence and Distribution of Volatile Organic Compounds in Conventional and Advanced Drinking Water Treatment Processes] Huan Jing Ke Xue= Huanjing Kexue. Dec, 2013 | Pubmed ID: 24640902 Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers Huijuan You*1, Shimin Le*2,3, Hu Chen2,4, Linyan Qin1, Jie Yan2,4,5 1School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 2Mechanobiology Institute, National University of Singapore, 3Department of Physics, National University of Singapore, 4Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Lab for Soft Functional Materials Research, Department of Physics, Xiamen University, 5Center for Bioimaging Sciences, National University of Singapore JoVE 56328 생화학
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers Huijuan You*1, Shimin Le*2,3, Hu Chen2,4, Linyan Qin1, Jie Yan2,4,5 1School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 2Mechanobiology Institute, National University of Singapore, 3Department of Physics, National University of Singapore, 4Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Lab for Soft Functional Materials Research, Department of Physics, Xiamen University, 5Center for Bioimaging Sciences, National University of Singapore JoVE 56328 생화학