Junhua Li Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology Chinese Academy of Sciences Biography Publications Institution JoVE Articles Junhua Li has not added a biography. If you are Junhua Li and would like to personalize this page please email our Author Liaison for assistance. Publications Safety and Immunogenicity of a Recombinant Tandem-repeat Dimeric RBD-based Protein Subunit Vaccine (ZF2001) Against COVID-19 in Adults: Two Randomised, Double-blind, Placebo-controlled, Phase 1 and 2 Trials The Lancet. Infectious Diseases. Mar, 2021 | Pubmed ID: 33773111 A Novel Bacteriophage Endolysin LysAB54 With High Antibacterial Activity Against Multiple Gram-Negative Microbes Frontiers in Cellular and Infection Microbiology. 2021 | Pubmed ID: 33738267 Population Bottlenecks and Intra-host Evolution During Human-to-Human Transmission of SARS-CoV-2 Frontiers in Medicine. 2021 | Pubmed ID: 33659260 Longitudinal Study of the Drug Resistance in of a Tertiary Hospital, China: Phenotypic Epidemiology Analysis (2013-2018) Infection and Drug Resistance. 2021 | Pubmed ID: 33628037 Intra-host Variation and Evolutionary Dynamics of SARS-CoV-2 Populations in COVID-19 Patients Genome Medicine. 02, 2021 | Pubmed ID: 33618765 Characterizing Dynamic Changes of Plasma Cell-free Echinococcus Granulosus DNA Before and After Cystic Echinococcosis Treatment Initiation Genomics. Mar, 2021 | Pubmed ID: 33383141 Developing Multiplex DdPCR Assays for SARS-CoV-2 Detection Based on Probe Mix and Amplitude Based Multiplexing Expert Review of Molecular Diagnostics. 01, 2021 | Pubmed ID: 33380245 [Expert Consensus on Microbiome Sequencing and Analysis] Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. Dec, 2020 | Pubmed ID: 33398950 A Path Toward SARS-CoV-2 Attenuation: Metabolic Pressure on CTP Synthesis Rules the Virus Evolution Genome Biology and Evolution. 12, 2020 | Pubmed ID: 33125064 A Compromised Specific Humoral Immune Response Against the SARS-CoV-2 Receptor-binding Domain is Related to Viral Persistence and Periodic Shedding in the Gastrointestinal Tract Cellular & Molecular Immunology. 11, 2020 | Pubmed ID: 33037400 Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China Kidney Diseases (Basel, Switzerland). Jul, 2020 | Pubmed ID: 32903303 Roles of Oxygen Vacancies in the Bulk and Surface of CeO for Toluene Catalytic Combustion Environmental Science & Technology. 10, 2020 | Pubmed ID: 32841009 Assessment of Fecal DNA Extraction Protocols for Metagenomic Studies GigaScience. 07, 2020 | Pubmed ID: 32657325 Multiple Approaches for Massively Parallel Sequencing of SARS-CoV-2 Genomes Directly from Clinical Samples Genome Medicine. 06, 2020 | Pubmed ID: 32605661 A Catalog of Microbial Genes from the Bovine Rumen Unveils a Specialized and Diverse Biomass-degrading Environment GigaScience. 06, 2020 | Pubmed ID: 32473013 Comprehensive Characterization of Plasma Cell-free Echinococcus Spp. DNA in Echinococcosis Patients using Ultra-high-throughput Sequencing PLoS Neglected Tropical Diseases. 04, 2020 | Pubmed ID: 32282820 Cu-catalyzed Oxygenation of Alkene-tethered Amides with O Unactivated C[double Bond, Length As M-dash]C Bond Cleavage: a Direct Approach to Cyclic Imides Chemical Science. Oct, 2019 | Pubmed ID: 31827752 Drivers of Improved PM Air Quality in China from 2013 to 2017 Proceedings of the National Academy of Sciences of the United States of America. 12, 2019 | Pubmed ID: 31740599 Distinct Gut Metagenomics and Metaproteomics Signatures in Prediabetics and Treatment-naïve Type 2 Diabetics EBioMedicine. Sep, 2019 | Pubmed ID: 31492563 Construction of Lentivirus-Based Reference Material for RT-PCR Detection of Middle East Respiratory Syndrome Coronavirus and Its Application in External Quality Assessment Journal of Nanoscience and Nanotechnology. Sep, 2019 | Pubmed ID: 30961704 1,520 Reference Genomes from Cultivated Human Gut Bacteria Enable Functional Microbiome Analyses Nature Biotechnology. 02, 2019 | Pubmed ID: 30718868 Exploring a Phage-based Real-time PCR Assay for Diagnosing Acinetobacter Baumannii Bloodstream Infections with High Sensitivity Analytica Chimica Acta. Dec, 2018 | Pubmed ID: 30442396 The Metagenome of the Female Upper Reproductive Tract GigaScience. 10, 2018 | Pubmed ID: 30192933 Virulence Attenuation and Immune Clearance Mediated by a Phage Lysin-derived Protein The EMBO Journal. 09, 2018 | Pubmed ID: 30037823 OsMAPK3 Phosphorylates OsbHLH002/OsICE1 and Inhibits Its Ubiquitination to Activate OsTPP1 and Enhances Rice Chilling Tolerance Developmental Cell. 12, 2017 | Pubmed ID: 29257952 Analyses of Gut Microbiota and Plasma Bile Acids Enable Stratification of Patients for Antidiabetic Treatment Nature Communications. 11, 2017 | Pubmed ID: 29176714 The Microbiota Continuum Along the Female Reproductive Tract and Its Relation to Uterine-related Diseases Nature Communications. 10, 2017 | Pubmed ID: 29042534 The Gut Microbiome in Atherosclerotic Cardiovascular Disease Nature Communications. 10, 2017 | Pubmed ID: 29018189 Heterogeneous Reactions Between Toluene and NO on Mineral Particles Under Simulated Atmospheric Conditions Environmental Science & Technology. Sep, 2017 | Pubmed ID: 28728409 Accurate Detection of Methicillin-Resistant Staphylococcus Aureus in Mixtures by Use of Single-Bacterium Duplex Droplet Digital PCR Journal of Clinical Microbiology. 10, 2017 | Pubmed ID: 28724560 Gut Microbiome and Serum Metabolome Alterations in Obesity and After Weight-loss Intervention Nature Medicine. Jul, 2017 | Pubmed ID: 28628112 Lipidomic Profiling Reveals Distinct Differences in Plasma Lipid Composition in Healthy, Prediabetic, and Type 2 Diabetic Individuals GigaScience. 07, 2017 | Pubmed ID: 28505362 Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome Cell Systems. Dec, 2016 | Pubmed ID: 27818083 A Catalog of the Mouse Gut Metagenome Nature Biotechnology. Oct, 2015 | Pubmed ID: 26414350 Removal of Antimonite (Sb(III)) and Antimonate (Sb(V)) from Aqueous Solution Using Carbon Nanofibers That Are Decorated with Zirconium Oxide (ZrO2) Environmental Science & Technology. Sep, 2015 | Pubmed ID: 26301862 The Oral and Gut Microbiomes Are Perturbed in Rheumatoid Arthritis and Partly Normalized After Treatment Nature Medicine. Aug, 2015 | Pubmed ID: 26214836 Decreasing Effect and Mechanism of FeSO4 Seed Particles on Secondary Organic Aerosol in α-pinene Photooxidation Environmental Pollution (Barking, Essex : 1987). Oct, 2014 | Pubmed ID: 25014016 The Abatement of Major Pollutants in Air and Water by Environmental Catalysis Frontiers of Environmental Science & Engineering. 2013 | Pubmed ID: 32215223 Ectopic Expression of WUS in Hypocotyl Promotes Cell Division Via GRP23 in Arabidopsis PloS One. 2013 | Pubmed ID: 24086632 The E3 Ligase AtRDUF1 Positively Regulates Salt Stress Responses in Arabidopsis Thaliana PloS One. 2013 | Pubmed ID: 23951086 Expression Pattern, Promoter Activity and Bactericidal Property of β-defensin from the Mandarin Fish Siniperca Chuatsi Fish & Shellfish Immunology. Sep, 2012 | Pubmed ID: 22705342 RNAi Knockdown of Oryza Sativa Root Meander Curling Gene Led to Altered Root Development and Coiling Which Were Mediated by Jasmonic Acid Signalling in Rice Plant, Cell & Environment. Jun, 2007 | Pubmed ID: 17470145 Cloning and Expression Analysis of TSK1, a Wheat SKP1 Homologue, and Functional Comparison with Arabidopsis ASK1 in Male Meiosis and Auxin Signalling Functional Plant Biology : FPB. May, 2006 | Pubmed ID: 32689244 Over-expression of OsAGAP, an ARF-GAP, Interferes with Auxin Influx, Vesicle Trafficking and Root Development The Plant Journal : for Cell and Molecular Biology. Nov, 2006 | Pubmed ID: 17059407 Two-Step Reverse Transcription Droplet Digital PCR Protocols for SARS-CoV-2 Detection and Quantification Raphael Nyaruaba1,2,3, Xiaohong Li1, Caroline Mwaliko2,3,4, Changchang Li1, Matilu Mwau5, Nelson Odiwour1,2,3, Elishiba Muturi1,2,3, Caroline Muema1,2,3, Junhua Li1, Junping Yu1, Hongping Wei1 1Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, 2International College, University of Chinese Academy of Sciences, 3Sino-Africa Joint Research Center, 4CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, 5Center for Infectious and Parasitic Diseases Control Research, Kenya Medical Research Institute JoVE 62295 생물학
Two-Step Reverse Transcription Droplet Digital PCR Protocols for SARS-CoV-2 Detection and Quantification Raphael Nyaruaba1,2,3, Xiaohong Li1, Caroline Mwaliko2,3,4, Changchang Li1, Matilu Mwau5, Nelson Odiwour1,2,3, Elishiba Muturi1,2,3, Caroline Muema1,2,3, Junhua Li1, Junping Yu1, Hongping Wei1 1Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, 2International College, University of Chinese Academy of Sciences, 3Sino-Africa Joint Research Center, 4CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, 5Center for Infectious and Parasitic Diseases Control Research, Kenya Medical Research Institute JoVE 62295 생물학