Reinis Vilskersts Laboratory of Pharmaceutical Pharmacology Latvian Institute of Organic Synthesis Biography Publications Institution JoVE Articles Reinis Vilskersts has not added a biography. If you are Reinis Vilskersts and would like to personalize this page please email our Author Liaison for assistance. Publications Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19 International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008470 Low Cardiac Content of Long-chain Acylcarnitines in TMLHE Knockout Mice Prevents Ischaemia-reperfusion-induced Mitochondrial and Cardiac Damage Free Radical Biology & Medicine. 12, 2021 | Pubmed ID: 34728372 Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33520996 Rats with Congenital Hydronephrosis Show Increased Susceptibility to Renal Ischemia-reperfusion Injury Physiological Reports. 11, 2020 | Pubmed ID: 33207081 Inhibition of CPT2 Exacerbates Cardiac Dysfunction and Inflammation in Experimental Endotoxaemia Journal of Cellular and Molecular Medicine. 10, 2020 | Pubmed ID: 32896106 4-Pyridinio-1,4-Dihydropyridines As Calcium Ion Transport Modulators: Antagonist, Agonist, and Dual Action Oxidative Medicine and Cellular Longevity. 2020 | Pubmed ID: 32308799 Sulfonyl Group Dance: A Tool for the Synthesis of 6-Azido-2-sulfonylpurine Derivatives The Journal of Organic Chemistry. 04, 2020 | Pubmed ID: 32150410 Delivery Systems for Birch-bark Triterpenoids and Their Derivatives in Anticancer Research Current Medicinal Chemistry. 2020 | Pubmed ID: 29848269 Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia Shock (Augusta, Ga.). 12, 2019 | Pubmed ID: 30640252 Acute and Long-term Administration of Palmitoylcarnitine Induces Muscle-specific Insulin Resistance in Mice BioFactors (Oxford, England). Sep, 2017 | Pubmed ID: 28759135 Trimethylamine N-oxide Impairs Pyruvate and Fatty Acid Oxidation in Cardiac Mitochondria Toxicology Letters. Feb, 2017 | Pubmed ID: 28049038 Long-chain Acylcarnitines Determine Ischaemia/reperfusion-induced Damage in Heart Mitochondria The Biochemical Journal. 05, 2016 | Pubmed ID: 26936967 Pharmacological Effects of Meldonium: Biochemical Mechanisms and Biomarkers of Cardiometabolic Activity Pharmacological Research. 11, 2016 | Pubmed ID: 26850121 Methyl-γ-butyrobetaine Decreases Levels of Acylcarnitines and Attenuates the Development of Atherosclerosis Vascular Pharmacology. Sep, 2015 | Pubmed ID: 25989106 Selective Inhibition of OCTN2 is More Effective Than Inhibition of Gamma-butyrobetaine Dioxygenase to Decrease the Availability of L-carnitine and to Reduce Myocardial Infarct Size Pharmacological Research. Jul, 2014 | Pubmed ID: 24836867 Magnesium Nitrate Attenuates Blood Pressure Rise in SHR Rats Magnesium Research. Jan-Mar, 2014 | Pubmed ID: 24827813 The Heart is Better Protected Against Myocardial Infarction in the Fed State Compared to the Fasted State Metabolism: Clinical and Experimental. Jan, 2014 | Pubmed ID: 24140100 Elevated Vascular γ-butyrobetaine Levels Attenuate the Development of High Glucose-induced Endothelial Dysfunction Clinical and Experimental Pharmacology & Physiology. Aug, 2013 | Pubmed ID: 23710938 Synthesis and Biological Evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide Stereoisomers As Novel Positive Allosteric Modulators of Sigma-1 Receptor Bioorganic & Medicinal Chemistry. May, 2013 | Pubmed ID: 23582449 Glyoxalase 1 and Glyoxalase 2 Activities in Blood and Neuronal Tissue Samples from Experimental Animal Models of Obesity and Type 2 Diabetes Mellitus The Journal of Physiological Sciences : JPS. Nov, 2012 | Pubmed ID: 22893478 The Cardioprotective Effect of Mildronate is Diminished After Co-treatment with L-carnitine Journal of Cardiovascular Pharmacology and Therapeutics. Jun, 2012 | Pubmed ID: 21903968 Administration of L-carnitine and Mildronate Improves Endothelial Function and Decreases Mortality in Hypertensive Dahl Rats Pharmacological Reports : PR. 2011 | Pubmed ID: 21857086 The Anti-inflammatory and Antinociceptive Effects of NF-kappaB Inhibitory Guanidine Derivative ME10092 International Immunopharmacology. Apr, 2010 | Pubmed ID: 20074673 Effects of Long-term Mildronate Treatment on Cardiac and Liver Functions in Rats Basic & Clinical Pharmacology & Toxicology. Dec, 2009 | Pubmed ID: 19663820 Protective Effects of Mildronate in an Experimental Model of Type 2 Diabetes in Goto-Kakizaki Rats British Journal of Pharmacology. Aug, 2009 | Pubmed ID: 19594753 Myocardial Infarct Size-limiting and Anti-arrhythmic Effects of Mildronate Orotate in the Rat Heart Cardiovascular Drugs and Therapy. Aug, 2009 | Pubmed ID: 19536647 Mildronate Decreases Carnitine Availability and Up-regulates Glucose Uptake and Related Gene Expression in the Mouse Heart Life Sciences. Oct, 2008 | Pubmed ID: 18801379 Mildronate, an Inhibitor of Carnitine Biosynthesis, Induces an Increase in Gamma-butyrobetaine Contents and Cardioprotection in Isolated Rat Heart Infarction Journal of Cardiovascular Pharmacology. Dec, 2006 | Pubmed ID: 17204911 Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion Edgars Liepinsh1, Janis Kuka1, Liga Zvejniece1, Reinis Vilskersts1, Maija Dambrova1 1Laboratory of Pharmaceutical Pharmacology, Latvian Institute of Organic Synthesis JoVE 62942 의학
Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion Edgars Liepinsh1, Janis Kuka1, Liga Zvejniece1, Reinis Vilskersts1, Maija Dambrova1 1Laboratory of Pharmaceutical Pharmacology, Latvian Institute of Organic Synthesis JoVE 62942 의학