Satoru Takahashi Laboratory Animal Resource Center and Trans-Border Medical Research Center University of Tsukuba Biography Publications Institution JoVE Articles Satoru Takahashi has not added a biography. If you are Satoru Takahashi and would like to personalize this page please email our Author Liaison for assistance. Publications Coordination Chemogenetics for Activation of GPCR-type Glutamate Receptors in Brain Tissue Nature Communications. Jun, 2022 | Pubmed ID: 35710788 Comparing Effects of Microgravity and Amyotrophic Lateral Sclerosis in the Mouse Ventral Lumbar Spinal Cord Molecular and Cellular Neurosciences. Jun, 2022 | Pubmed ID: 35660087 Summary of the Clinical Practice Guidelines for Penile Cancer 2021 by the Japanese Urological Association International Journal of Urology : Official Journal of the Japanese Urological Association. May, 2022 | Pubmed ID: 35643932 Identifying Potential Regulators of JAGGED1 Expression in Portal Mesenchymal Cells BMC Research Notes. May, 2022 | Pubmed ID: 35562782 Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells Viruses. 04, 2022 | Pubmed ID: 35458563 Generation of a Gal4-dependent Gene Recombination and Illuminating Mouse Experimental Animals. Apr, 2022 | Pubmed ID: 35444103 Inducible Systemic Deletion in Mice Leads to Transient Body Weight Loss Upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage International Journal of Molecular Sciences. Mar, 2022 | Pubmed ID: 35328622 Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood Stem Cells (Dayton, Ohio). 04, 2022 | Pubmed ID: 35304894 MafK Accelerates Mucosal Infection Through Caspase-3 Activation Aging. 03, 2022 | Pubmed ID: 35260530 Global Loss of Core 1-Derived -Glycans in Mice Leads to High Mortality Due to Acute Kidney Failure and Gastric Ulcers International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35163200 DAJIN Enables Multiplex Genotyping to Simultaneously Validate Intended and Unintended Target Genome Editing Outcomes PLoS Biology. 01, 2022 | Pubmed ID: 35041655 Gene Expression Changes Related to Bone Mineralization, Blood Pressure and Lipid Metabolism in Mouse Kidneys After Space Travel Kidney International. 01, 2022 | Pubmed ID: 34767829 Differential Involvement of Programmed Cell Death Ligands in Skin Immune Responses The Journal of Investigative Dermatology. 01, 2022 | Pubmed ID: 34310947 Albino Mice with the Point Mutation at the Tyrosinase Locus Show High Cholesterol Diet-induced NASH Susceptibility Scientific Reports. 11, 2021 | Pubmed ID: 34750345 A Multistate Stem Cell Dynamics Maintains Homeostasis in Mouse Spermatogenesis Cell Reports. 10, 2021 | Pubmed ID: 34686326 A Common Genetic Variant of a Mitochondrial RNA Processing Enzyme Predisposes to Insulin Resistance Science Advances. Sep, 2021 | Pubmed ID: 34559558 Author Correction: Study of Mouse Behavior in Different Gravity Environments Scientific Reports. Aug, 2021 | Pubmed ID: 34453068 Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction Cancers. Aug, 2021 | Pubmed ID: 34439392 Intergenerational Effect of Short-term Spaceflight in Mice IScience. Jul, 2021 | Pubmed ID: 34278272 Mathematical Analysis of the Effect of Portal Vein Cells on Biliary Epithelial Cell Differentiation Through the Delta-Notch Signaling Pathway BMC Research Notes. Jun, 2021 | Pubmed ID: 34187572 Nuclear Factor E2-related Factor 2 (NRF2) Deficiency Accelerates Fast Fibre Type Transition in Soleus Muscle During Space Flight Communications Biology. 06, 2021 | Pubmed ID: 34168270 Overexpression of Human BAG3 in Mice Causes Restrictive Cardiomyopathy Nature Communications. 06, 2021 | Pubmed ID: 34117258 Findings from Recent Studies by the Japan Aerospace Exploration Agency Examining Musculoskeletal Atrophy in Space and on Earth NPJ Microgravity. May, 2021 | Pubmed ID: 34039989 Radiation Inducible MafB Gene is Required for Thymic Regeneration Scientific Reports. 05, 2021 | Pubmed ID: 34001954 EXOC1 Plays an Integral Role in Spermatogonia Pseudopod Elongation and Spermatocyte Stable Syncytium Formation in Mice ELife. 05, 2021 | Pubmed ID: 33973520 Disruption of Entire Locus Leads to Embryonic Lethality by Diminished Gene Expression and Enhanced P53 Pathway ELife. 05, 2021 | Pubmed ID: 33949947 Transcriptome Analysis of Gravitational Effects on Mouse Skeletal Muscles Under Microgravity and Artificial 1 G Onboard Environment Scientific Reports. 04, 2021 | Pubmed ID: 33911096 Response to Correspondence on "Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation" Genome Biology. 04, 2021 | Pubmed ID: 33827648 Functional Analysis of Large MAF Transcription Factors and Elucidation of Their Relationships with Human Diseases Experimental Animals. Aug, 2021 | Pubmed ID: 33762508 Generation of Reconstituted Hemato-lymphoid Murine Embryos by Placental Transplantation into Embryos Lacking HSCs Scientific Reports. 02, 2021 | Pubmed ID: 33623082 Induction of Mutant Allele in Neurons in Late Infancy Increases Sleep Need The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 03, 2021 | Pubmed ID: 33558433 Effects of RORγt Overexpression on the Murine Central Nervous System Neuropsychopharmacology Reports. 03, 2021 | Pubmed ID: 33547881 Mobilization Efficiency is Critically Regulated by Fat Via Marrow PPARδ Haematologica. 06, 2021 | Pubmed ID: 33538151 Study of Mouse Behavior in Different Gravity Environments Scientific Reports. 01, 2021 | Pubmed ID: 33514775 FGF-23 from Erythroblasts Promotes Hematopoietic Progenitor Mobilization Blood. 03, 2021 | Pubmed ID: 33512467 Novel Method for Evaluating the Health Condition of Mice in Space Through a Video Downlink Experimental Animals. May, 2021 | Pubmed ID: 33487610 Mast4 Knockout Shows the Regulation of Spermatogonial Stem Cell Self-renewal Via the FGF2/ERM Pathway Cell Death and Differentiation. 05, 2021 | Pubmed ID: 33219327 Efficient Production of Large Deletion and Gene Fragment Knock-in Mice Mediated by Genome Editing with Cas9-mouse Cdt1 in Mouse Zygotes Methods (San Diego, Calif.). 07, 2021 | Pubmed ID: 32334080 Activation of CD8 T Cells Accelerates Anti-PD-1 Antibody-induced Psoriasis-like Dermatitis Through IL-6 Communications Biology. 10, 2020 | Pubmed ID: 33060784 Author Correction: Nrf2 Contributes to the Weight Gain of Mice During Space Travel Communications Biology. Oct, 2020 | Pubmed ID: 33028949 Suppressed ER-associated Degradation by Intraglomerular Cross Talk Between Mesangial Cells and Podocytes Causes Podocyte Injury in Diabetic Kidney Disease FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 11, 2020 | Pubmed ID: 32996639 Nrf2 Contributes to the Weight Gain of Mice During Space Travel Communications Biology. 09, 2020 | Pubmed ID: 32901092 Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β Genetics. 11, 2020 | Pubmed ID: 32878901 An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout Under MafA-Deficient Condition International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32764399 Aspects of Gene Therapy Products Using Current Genome-Editing Technology in Japan Human Gene Therapy. 10, 2020 | Pubmed ID: 32731837 Transcription Factor MafB in Podocytes Protects Against the Development of Focal Segmental Glomerulosclerosis Kidney International. 08, 2020 | Pubmed ID: 32622525 CRISPR/Cas9-based Genome Editing in Mice Uncovers 13 Testis- or Epididymis-enriched Genes Individually Dispensable for Male Reproduction† Biology of Reproduction. 08, 2020 | Pubmed ID: 32588039 Clinical Practice Guidelines for Bladder Cancer 2019 Update by the Japanese Urological Association: Summary of the Revision International Journal of Urology : Official Journal of the Japanese Urological Association. 09, 2020 | Pubmed ID: 32564429 Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine DR-mediated Sleep Reduction IScience. Jun, 2020 | Pubmed ID: 32563157 Reverse Genetics Reveals Single Gene of Every Candidate on Hybrid Sterility, X Chromosome QTL 2 (Hstx2) Are Dispensable for Spermatogenesis Scientific Reports. 06, 2020 | Pubmed ID: 32493902 Gender Difference in Development of Steatohepatitis in P62/Sqstm1 and Nrf2 Double-knockout Mice Experimental Animals. Nov, 2020 | Pubmed ID: 32493884 Pathway Modulates the Code Via Regulation During Axial Patterning in Vertebrates ELife. 05, 2020 | Pubmed ID: 32479258 Loss of the Conserved PKA Sites of SIK1 and SIK2 Increases Sleep Need Scientific Reports. 05, 2020 | Pubmed ID: 32457359 Ribosome Binding Protein GCN1 regulates the Cell Cycle and Cell Proliferation and is Essential for the Embryonic Development of Mice PLoS Genetics. 04, 2020 | Pubmed ID: 32324833 Lymphatic MAFB Regulates Vascular Patterning During Developmental and Pathological Lymphangiogenesis Angiogenesis. 08, 2020 | Pubmed ID: 32307629 Generation of B6-Ddx4 , a Novel CreERT2 Knock-in Line, for Germ Cell Lineage by CRISPR/Cas9 Genesis (New York, N.Y. : 2000). 07, 2020 | Pubmed ID: 32293787 Clinical Practice Guidelines for Bladder Cancer 2019 Edition by the Japanese Urological Association: Revision Working Position Paper International Journal of Urology : Official Journal of the Japanese Urological Association. May, 2020 | Pubmed ID: 32172529 Mice Lacking Core 1-derived O-glycan in Podocytes Develop Transient Proteinuria, Resulting in Focal Segmental Glomerulosclerosis Biochemical and Biophysical Research Communications. 03, 2020 | Pubmed ID: 31973821 C-MAF Deletion in Adult C57BL/6J Mice Induces Cataract Formation and Abnormal Differentiation of Lens Fiber Cells Experimental Animals. Apr, 2020 | Pubmed ID: 31969519 Transcription Factor C-Maf is a Checkpoint That Programs Macrophages in Lung Cancer The Journal of Clinical Investigation. 04, 2020 | Pubmed ID: 31945018 Phenotypic Analysis of Mice Carrying Human-type MAFB P.Leu239Pro Mutation Biochemical and Biophysical Research Communications. 03, 2020 | Pubmed ID: 31882119 RORγt Antagonist Improves Sjögren's Syndrome-like Sialadenitis Through Downregulation of CD25 Oral Diseases. May, 2020 | Pubmed ID: 31837283 Highly Efficient CRISPR-targeting of the Murine Hipp11 Intergenic Region Supports Inducible Human Transgene Expression Molecular Biology Reports. Feb, 2020 | Pubmed ID: 31811500 Uncovering the Role of MAFB in Glucagon Production and Secretion in Pancreatic α-cells Using a New α-cell-specific Mafb Conditional Knockout Mouse Model Experimental Animals. Apr, 2020 | Pubmed ID: 31787710 Transcription Factor MafB is a Marker of Tumor-associated Macrophages in Both Mouse and Humans Biochemical and Biophysical Research Communications. 01, 2020 | Pubmed ID: 31679694 Regulation of Bile Acid Metabolism in Mouse Models with Hydrophobic Bile Acid Composition Journal of Lipid Research. 01, 2020 | Pubmed ID: 31645370 Role of MafB in Macrophages Experimental Animals. Jan, 2020 | Pubmed ID: 31582643 Clec10a Regulates Mite-induced Dermatitis Science Immunology. 12, 2019 | Pubmed ID: 31811054 The Conserved Metalloprotease Invadolysin is Present in Invertebrate Haemolymph and Vertebrate Blood Biology Open. Nov, 2019 | Pubmed ID: 31615765 Male Mice, Caged in the International Space Station for 35 Days, Sire Healthy Offspring Scientific Reports. 09, 2019 | Pubmed ID: 31551430 Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: a Multi-center Evaluation Genome Biology. 08, 2019 | Pubmed ID: 31446895 Lysophosphatidic Acid-induced YAP/TAZ Activation Promotes Developmental Angiogenesis by Repressing Notch Ligand Dll4 The Journal of Clinical Investigation. 07, 2019 | Pubmed ID: 31335323 MafB Is Important for Pancreatic β-Cell Maintenance Under a MafA-Deficient Condition Molecular and Cellular Biology. 09, 2019 | Pubmed ID: 31208980 Elevated Maternal Retinoic Acid-related Orphan Receptor-γt Enhances the Effect of Polyinosinic-polycytidylic Acid in Inducing Fetal Loss Experimental Animals. Nov, 2019 | Pubmed ID: 31178537 PRRT2 Mutations in Japanese Patients with Benign Infantile Epilepsy and Paroxysmal Kinesigenic Dyskinesia Seizure. Oct, 2019 | Pubmed ID: 31154286 Spiral Ganglion Cell Degeneration-induced Deafness As a Consequence of Reduced GATA Factor Activity Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Aug, 2019 | Pubmed ID: 31141264 Down-regulation of GATA1-dependent Erythrocyte-related Genes in the Spleens of Mice Exposed to a Space Travel Scientific Reports. 05, 2019 | Pubmed ID: 31114014 Neuron-specific Mafb Knockout Causes Growth Retardation Accompanied by an Impaired Growth Hormone/insulin-like Growth Factor I Axis Experimental Animals. Nov, 2019 | Pubmed ID: 31092767 Transcription Factor T-bet Attenuates the Development of Elastase-induced Emphysema in Mice American Journal of Respiratory Cell and Molecular Biology. 10, 2019 | Pubmed ID: 30965014 EFCAB2 is a Novel Calcium-binding Protein in Mouse Testis and Sperm PloS One. 2019 | Pubmed ID: 30933994 Notch Signaling in Nestin-Expressing Cells in the Bone Marrow Maintains Erythropoiesis Via Macrophage Integrity Stem Cells (Dayton, Ohio). 07, 2019 | Pubmed ID: 30932281 The Chromatin-binding Protein Phf6 Restricts the Self-renewal of Hematopoietic Stem Cells Blood. 06, 2019 | Pubmed ID: 30917958 KOnezumi: a Web Application for Automating Gene Disruption Strategies to Generate Knockout Mice Bioinformatics (Oxford, England). 09, 2019 | Pubmed ID: 30726877 Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells Journal of the American Society of Nephrology : JASN. 02, 2019 | Pubmed ID: 30635375 Generating Vegfr3 Reporter Transgenic Mouse Expressing Membrane-tagged Venus for Visualization of VEGFR3 Expression in Vascular and Lymphatic Endothelial Cells PloS One. 2019 | Pubmed ID: 30601868 Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche Cell Stem Cell. 01, 2019 | Pubmed ID: 30581080 TRMT2A is a Novel Cell Cycle Regulator That Suppresses Cell Proliferation Biochemical and Biophysical Research Communications. 01, 2019 | Pubmed ID: 30502085 Mice Harboring an MCTO Mutation Exhibit Renal Failure Resembling Nephropathy in Human Patients Experimental Animals. Feb, 2019 | Pubmed ID: 30369533 Important Cardiac Transcription Factor Genes Are Accompanied by Bidirectional Long Non-coding RNAs BMC Genomics. Dec, 2018 | Pubmed ID: 30587117 Klf5 Suppresses ERK Signaling in Mouse Pluripotent Stem Cells PloS One. 2018 | Pubmed ID: 30452437 A Novel IRFP-Incorporated in Vivo Murine Atherosclerosis Imaging System Scientific Reports. 09, 2018 | Pubmed ID: 30266983 A Single Phosphorylation Site of SIK3 Regulates Daily Sleep Amounts and Sleep Need in Mice Proceedings of the National Academy of Sciences of the United States of America. 10, 2018 | Pubmed ID: 30254177 Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis International Journal of Molecular Sciences. Aug, 2018 | Pubmed ID: 30154332 De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome American Journal of Human Genetics. 09, 2018 | Pubmed ID: 30146126 Aberrant Imprinting in Mouse Trophoblast Stem Cells Established from Somatic Cell Nuclear Transfer-derived Embryos Epigenetics. 2018 | Pubmed ID: 30079806 ZMYND10 Functions in a Chaperone Relay During Axonemal Dynein Assembly ELife. 06, 2018 | Pubmed ID: 29916806 Macrophages Switch Their Phenotype by Regulating Maf Expression During Different Phases of Inflammation Journal of Immunology (Baltimore, Md. : 1950). 07, 2018 | Pubmed ID: 29907708 Quantitative Phosphoproteomic Analysis of the Molecular Substrates of Sleep Need Nature. 06, 2018 | Pubmed ID: 29899451 A Mutation in Transcription Factor MAFB Causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome Kidney International. 08, 2018 | Pubmed ID: 29779709 Long-term Hindlimb Unloading Causes a Preferential Reduction of Medullary Thymic Epithelial Cells Expressing Autoimmune Regulator (Aire) Biochemical and Biophysical Research Communications. 06, 2018 | Pubmed ID: 29753741 S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming Through Enhanced Cell-Cycle Exit International Journal of Molecular Sciences. May, 2018 | Pubmed ID: 29734659 Optical Clearing of the Pancreas for Visualization of Mature β-cells and Vessels in Mice Islets. 05, 2018 | Pubmed ID: 29617192 Visualization of Endothelial Cell Cycle Dynamics in Mouse Using the Flt-1/eGFP-anillin System Angiogenesis. 05, 2018 | Pubmed ID: 29417260 MafB Is Critical for Glucagon Production and Secretion in Mouse Pancreatic α Cells Molecular and Cellular Biology. 04, 2018 | Pubmed ID: 29378833 MAFB is Dispensable for the Fetal Testis Morphogenesis and the Maintenance of Spermatogenesis in Adult Mice PloS One. 2018 | Pubmed ID: 29324782 Time-course Transcriptome Analysis of Human Cellular Reprogramming from Multiple Cell Types Reveals the Drastic Change Occurs Between the Mid Phase and the Late Phase BMC Genomics. 01, 2018 | Pubmed ID: 29298685 Incomplete Clearance of Apoptotic Cells by Core 1-derived O-glycan-deficient Resident Peritoneal Macrophages Biochemical and Biophysical Research Communications. 01, 2018 | Pubmed ID: 29247646 Isl1β Overexpression With Key β Cell Transcription Factors Enhances Glucose-Responsive Hepatic Insulin Production and Secretion Endocrinology. 02, 2018 | Pubmed ID: 29220426 Transcription Factor MafB May Play an Important Role in Secondary Hyperparathyroidism Kidney International. 01, 2018 | Pubmed ID: 28964572 Postnatal Lethality and Chondrodysplasia in Mice Lacking Both Chondroitin Sulfate N-acetylgalactosaminyltransferase-1 and -2 PloS One. 2017 | Pubmed ID: 29287114 Co-chaperone BAG2 Determines the Pro-oncogenic Role of Cathepsin B in Triple-Negative Breast Cancer Cells Cell Reports. Dec, 2017 | Pubmed ID: 29212038 MafB is a Critical Regulator of Complement Component C1q Nature Communications. 11, 2017 | Pubmed ID: 29167450 Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor C-Maf Frontiers in Immunology. 2017 | Pubmed ID: 29163480 Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation Scientific Reports. 10, 2017 | Pubmed ID: 29062064 Development of New Experimental Platform 'MARS'-Multiple Artificial-gravity Research System-to Elucidate the Impacts of Micro/partial Gravity on Mice Scientific Reports. 09, 2017 | Pubmed ID: 28883615 T-bet, but Not Gata3, Overexpression is Detrimental in a Neurotropic Viral Infection Scientific Reports. 09, 2017 | Pubmed ID: 28874814 Maintains the Balance of Primitive Endoderm Versus Epiblast Specification During Mouse Embryonic Development by Suppression of Development (Cambridge, England). 10, 2017 | Pubmed ID: 28870993 The Effects of Heat Stress on Morphological Properties and Intracellular Signaling of Denervated and Intact Soleus Muscles in Rats Physiological Reports. Aug, 2017 | Pubmed ID: 28784851 Simple Generation of Hairless Mice for in Vivo Imaging Experimental Animals. Oct, 2017 | Pubmed ID: 28717054 Effects of Gravity Changes on Gene Expression of BDNF and Serotonin Receptors in the Mouse Brain PloS One. 2017 | Pubmed ID: 28591153 The Small G Protein Arf6 Expressed in Keratinocytes by HGF Stimulation is a Regulator for Skin Wound Healing Scientific Reports. 04, 2017 | Pubmed ID: 28429746 Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice Scientific Reports. 04, 2017 | Pubmed ID: 28425492 MAFB Prevents Excess Inflammation After Ischemic Stroke by Accelerating Clearance of Damage Signals Through MSR1 Nature Medicine. Jun, 2017 | Pubmed ID: 28394332 GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion Molecular and Cellular Biology. 06, 2017 | Pubmed ID: 28320875 Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress Cell Reports. 02, 2017 | Pubmed ID: 28228267 SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28196692 Impact of a Simulated Gravity Load for Atmospheric Reentry, 10 g for 2 min, on Conscious Mice The Journal of Physiological Sciences : JPS. Jul, 2017 | Pubmed ID: 28185235 MafB is Required for Development of the Hindbrain Choroid Plexus Biochemical and Biophysical Research Communications. 01, 2017 | Pubmed ID: 28025141 Peripherally Administered Orexin Improves Survival of Mice with Endotoxin Shock ELife. 12, 2016 | Pubmed ID: 28035899 TIARP Attenuates Autoantibody-mediated Arthritis Via the Suppression of Neutrophil Migration by Reducing CXCL2/CXCR2 and IL-6 Expression Scientific Reports. 12, 2016 | Pubmed ID: 27995997 Forward-genetics Analysis of Sleep in Randomly Mutagenized Mice Nature. 11, 2016 | Pubmed ID: 27806374 Ophiocordyceps Formosana Improves Hyperglycemia and Depression-like Behavior in an STZ-induced Diabetic Mouse Model BMC Complementary and Alternative Medicine. Aug, 2016 | Pubmed ID: 27553852 MafB Deficiency Accelerates the Development of Obesity in Mice FEBS Open Bio. 06, 2016 | Pubmed ID: 27419056 Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells PloS One. 2016 | Pubmed ID: 27409080 Aberrant PD-L1 Expression Through 3'-UTR Disruption in Multiple Cancers Nature. 06, 2016 | Pubmed ID: 27281199 Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation The Journal of Investigative Dermatology. 09, 2016 | Pubmed ID: 27208706 Germline Recombination in a Novel Cre Transgenic Line, Prl3b1-Cre Mouse Genesis (New York, N.Y. : 2000). 07, 2016 | Pubmed ID: 27124574 Generation of CRISPR/Cas9-mediated Bicistronic Knock-in Ins1-cre Driver Mice Experimental Animals. Jul, 2016 | Pubmed ID: 27053096 Differential Expression Patterns of MafB and C-Maf in Macrophages in Vivo and in Vitro Biochemical and Biophysical Research Communications. Apr, 2016 | Pubmed ID: 26996125 Identification, Localization, and Functional Analysis of the Homologues of Mouse CABS1 Protein in Porcine Testis Experimental Animals. Jul, 2016 | Pubmed ID: 26960363 Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming PloS One. 2016 | Pubmed ID: 26943822 β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development PloS One. 2016 | Pubmed ID: 26901059 Ground-based Assessment of JAXA Mouse Habitat Cage Unit by Mouse Phenotypic Studies Experimental Animals. May, 2016 | Pubmed ID: 26822934 Overexpression of RORγt Enhances Pulmonary Inflammation After Infection with Mycobacterium Avium PloS One. 2016 | Pubmed ID: 26784959 Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells Stem Cells (Dayton, Ohio). Feb, 2016 | Pubmed ID: 26523946 A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets PloS One. 2015 | Pubmed ID: 26659409 Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice PloS One. 2015 | Pubmed ID: 26513242 Peri-implantation Lethality in Mice Carrying Megabase-scale Deletion on 5qc3.3 is Caused by Exoc1 Null Mutation Scientific Reports. Sep, 2015 | Pubmed ID: 26346620 Clinicopathological Characteristics and Oncological Outcomes in Patients with Renal Cell Carcinoma Registered in 2007: The First Large-scale Multicenter Study from the Cancer Registration Committee of the Japanese Urological Association International Journal of Urology : Official Journal of the Japanese Urological Association. Sep, 2015 | Pubmed ID: 26332059 Arf6 Regulates Tumour Angiogenesis and Growth Through HGF-induced Endothelial β1 Integrin Recycling Nature Communications. 2015 | Pubmed ID: 26239146 Feasibility of a Short-Arm Centrifuge for Mouse Hypergravity Experiments PloS One. 2015 | Pubmed ID: 26221724 Th2-biased GATA-3 Transgenic Mice Developed Severe Experimental Peritoneal Fibrosis Compared with Th1-biased T-bet and Th17-biased RORγt Transgenic Mice Experimental Animals. 2015 | Pubmed ID: 26156402 MafB Antagonizes Phenotypic Alteration Induced by GM-CSF in Microglia Biochemical and Biophysical Research Communications. Jul 17-24, 2015 | Pubmed ID: 25998393 Involvement of RORγt-overexpressing T Cells in the Development of Autoimmune Arthritis in Mice Arthritis Research & Therapy. Apr, 2015 | Pubmed ID: 25928901 Role of Large MAF Transcription Factors in the Mouse Endocrine Pancreas Experimental Animals. 2015 | Pubmed ID: 25912440 Lateralization, Maturation, and Anteroposterior Topography in the Lateral Habenula Revealed by ZIF268/EGR1 Immunoreactivity and Labeling History of Neuronal Activity Neuroscience Research. Jun, 2015 | Pubmed ID: 25637311 A Crucial Role of RORγt in the Development of Spontaneous Sialadenitis-like Sjögren's Syndrome Journal of Immunology (Baltimore, Md. : 1950). Jan, 2015 | Pubmed ID: 25411202 T-cell-restricted T-bet Overexpression Induces Aberrant Hematopoiesis of Myeloid Cells and Impairs Function of Macrophages in the Lung Blood. Jan, 2015 | Pubmed ID: 25349175 Th17-biased RORγt Transgenic Mice Become Susceptible to a Viral Model for Multiple Sclerosis Brain, Behavior, and Immunity. Jan, 2015 | Pubmed ID: 25046854 Generation of Insulin-producing Cells from the Mouse Liver Using β Cell-related Gene Transfer Including Mafa and Mafb PloS One. 2014 | Pubmed ID: 25397325 Sexually Dimorphic Expression of Mafb Regulates Masculinization of the Embryonic Urethral Formation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25362053 RORγt, but Not T-bet, Overexpression Exacerbates an Autoimmune Model for Multiple Sclerosis Journal of Neuroimmunology. Nov, 2014 | Pubmed ID: 25288300 MafA is Required for Postnatal Proliferation of Pancreatic β-cells PloS One. 2014 | Pubmed ID: 25126749 In Vivo Image Analysis Using IRFP Transgenic Mice Experimental Animals. 2014 | Pubmed ID: 25077761 Simple Generation of Albino C57BL/6J Mice with G291T Mutation in the Tyrosinase Gene by the CRISPR/Cas9 System Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 2014 | Pubmed ID: 24879364 Generation and Characterization of Ins1-cre-driver C57BL/6N for Exclusive Pancreatic Beta Cell-specific Cre-loxP Recombination Experimental Animals. 2014 | Pubmed ID: 24770644 Overexpression of GATA-3 in T Cells Accelerates Dextran Sulfate Sodium-induced Colitis Experimental Animals. 2014 | Pubmed ID: 24770638 Overexpression of Mafb in Podocytes Protects Against Diabetic Nephropathy Journal of the American Society of Nephrology : JASN. Nov, 2014 | Pubmed ID: 24722438 T-bet and Eomes Instruct the Development of Two Distinct Natural Killer Cell Lineages in the Liver and in the Bone Marrow The Journal of Experimental Medicine. Mar, 2014 | Pubmed ID: 24516120 O-linked Glycosylation Determines the Nephritogenic Potential of IgA Rheumatoid Factor Journal of the American Society of Nephrology : JASN. Jun, 2014 | Pubmed ID: 24511137 Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells Cell Stem Cell. Feb, 2014 | Pubmed ID: 24506885 Regulation of an Autoimmune Model for Multiple Sclerosis in Th2-biased GATA3 Transgenic Mice International Journal of Molecular Sciences. Jan, 2014 | Pubmed ID: 24463292 Role of Th1/Th17 Balance Regulated by T-bet in a Mouse Model of Mycobacterium Avium Complex Disease Journal of Immunology (Baltimore, Md. : 1950). Feb, 2014 | Pubmed ID: 24446514 MafB Promotes Atherosclerosis by Inhibiting Foam-cell Apoptosis Nature Communications. 2014 | Pubmed ID: 24445679 Novel ROSA26 Cre-reporter Knock-in C57BL/6N Mice Exhibiting Green Emission Before and Red Emission After Cre-mediated Recombination Experimental Animals. 2013 | Pubmed ID: 24172193 Influence of Inhibitory Serotonergic Inputs to Orexin/hypocretin Neurons on the Diurnal Rhythm of Sleep and Wakefulness Sleep. Sep, 2013 | Pubmed ID: 23997373 In Vivo Function and Evolution of the Eutherian-specific Pluripotency Marker UTF1 PloS One. 2013 | Pubmed ID: 23874519 C1galt1-deficient Mice Exhibit Thrombocytopenia Due to Abnormal Terminal Differentiation of Megakaryocytes Blood. Aug, 2013 | Pubmed ID: 23794065 Bioluminescence Imaging of β Cells and Intrahepatic Insulin Gene Activity Under Normal and Pathological Conditions PloS One. 2013 | Pubmed ID: 23593212 A Bacterial Artificial Chromosome Transgene with Polymorphic Cd72 Inhibits the Development of Glomerulonephritis and Vasculitis in MRL-Faslpr Lupus Mice Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23365086 Transcription Factors GATA-3 and RORγt Are Important for Determining the Phenotype of Allergic Airway Inflammation in a Murine Model of Asthma Journal of Immunology (Baltimore, Md. : 1950). Feb, 2013 | Pubmed ID: 23293351 Nrf2 in Bone Marrow-derived Cells Positively Contributes to the Advanced Stage of Atherosclerotic Plaque Formation Free Radical Biology & Medicine. Dec, 2012 | Pubmed ID: 23051009 Delayed Cutaneous Wound Healing in Fam129b/Minerva-deficient Mice Journal of Biochemistry. Dec, 2012 | Pubmed ID: 22977259 Murine Tumor Necrosis Factor α-induced Adipose-related Protein (tumor Necrosis Factor α-induced Protein 9) Deficiency Leads to Arthritis Via Interleukin-6 Overproduction with Enhanced NF-κB, STAT-3 Signaling, and Dysregulated Apoptosis of Macrophages Arthritis and Rheumatism. Dec, 2012 | Pubmed ID: 22886597 Noninvasive Monitoring of β-cell Mass and Fetal β-cell Genesis in Mice Using Bioluminescence Imaging Experimental Animals. 2012 | Pubmed ID: 22850644 Overexpression of RORγt Under Control of the CD2 Promoter Induces Polyclonal Plasmacytosis and Autoantibody Production in Transgenic Mice European Journal of Immunology. Aug, 2012 | Pubmed ID: 22623033 Genome-wide Identification of Endothelial Cell-enriched Genes in the Mouse Embryo Blood. Jul, 2012 | Pubmed ID: 22535667 Study of Normal and Pathological Blood Vessel Morphogenesis in Flt1-tdsRed BAC Tg Mice Genesis (New York, N.Y. : 2000). Jul, 2012 | Pubmed ID: 22489010 Organ-specific Sulfation Patterns of Heparan Sulfate Generated by Extracellular Sulfatases Sulf1 and Sulf2 in Mice The Journal of Biological Chemistry. Mar, 2012 | Pubmed ID: 22298771 A Novel Diabetes Mellitus Mouse Model, MAFA-deficient and Beta Cell-specific MAFK-overexpressing Hybrid Transgenic Mice, Developed Severe Diabetic Nephropathy and Improved with TCV-116 (candesartan Cilexetil) Treatment Experimental Animals. 2012 | Pubmed ID: 22293672 Prostate Cancer Chemoprevention Study: an Investigative Randomized Control Study Using Purified Isoflavones in Men with Rising Prostate-specific Antigen Cancer Science. Jan, 2012 | Pubmed ID: 21988617 Overexpression of T-bet Gene Regulates Murine Autoimmune Arthritis Arthritis and Rheumatism. Jan, 2012 | Pubmed ID: 21905017 Combinatorial Motif Analysis of Regulatory Gene Expression in Mafb Deficient Macrophages BMC Systems Biology. 2011 | Pubmed ID: 22784578 Molecular Basis for Flk1 Expression in Hemato-cardiovascular Progenitors in the Mouse Development (Cambridge, England). Dec, 2011 | Pubmed ID: 22071109 The E3 Ubiquitin Ligase Activity of Trip12 is Essential for Mouse Embryogenesis PloS One. 2011 | Pubmed ID: 22028794 Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7α (Fbw7α) Causes Hepatosteatosis Through Krüppel-like Factor 5 (KLF5)/peroxisome Proliferator-activated Receptor γ2 (PPARγ2) Pathway but Not SREBP-1c Protein in Mice The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21911492 Acute Optogenetic Silencing of Orexin/hypocretin Neurons Induces Slow-wave Sleep in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2011 | Pubmed ID: 21775598 MetaDBSite: a Meta Approach to Improve Protein DNA-binding Sites Prediction BMC Systems Biology. Jun, 2011 | Pubmed ID: 21689482 C-Maf Plays a Crucial Role for the Definitive Erythropoiesis That Accompanies Erythroblastic Island Formation in the Fetal Liver Blood. Aug, 2011 | Pubmed ID: 21628412 Isolation and Function of Mouse Tissue Resident Vascular Precursors Marked by Myelin Protein Zero The Journal of Experimental Medicine. May, 2011 | Pubmed ID: 21536740 Marked Induction of C-Maf Protein During Th17 Cell Differentiation and Its Implication in Memory Th Cell Development The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21402704 RNA Content in the Nucleolus Alters P53 Acetylation Via MYBBP1A The EMBO Journal. Mar, 2011 | Pubmed ID: 21297583 Two Distinct Origins for Leydig Cell Progenitors in the Fetal Testis Developmental Biology. Apr, 2011 | Pubmed ID: 21255566 A Novel Transgenic Mouse Model of the Human Multiple Myeloma Chromosomal Translocation T(14;16)(q32;q23) Cancer Research. Jan, 2011 | Pubmed ID: 21224354 Chondroitin Sulfate N-acetylgalactosaminyltransferase 1 is Necessary for Normal Endochondral Ossification and Aggrecan Metabolism The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21148564 Flk1-GFP BAC Tg Mice: an Animal Model for the Study of Blood Vessel Development Experimental Animals. 2010 | Pubmed ID: 21030789 Maf Promotes Osteoblast Differentiation in Mice by Mediating the Age-related Switch in Mesenchymal Cell Differentiation The Journal of Clinical Investigation. Oct, 2010 | Pubmed ID: 20877012 Insulin Transactivator MafA Regulates Intrathymic Expression of Insulin and Affects Susceptibility to Type 1 Diabetes Diabetes. Oct, 2010 | Pubmed ID: 20682694 Lack of Lacto/neolacto-glycolipids Enhances the Formation of Glycolipid-enriched Microdomains, Facilitating B Cell Activation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20547865 Impairment of Host Defense Against Disseminated Candidiasis in Mice Overexpressing GATA-3 Infection and Immunity. May, 2010 | Pubmed ID: 20231412 Loss of the BMP Antagonist USAG-1 Ameliorates Disease in a Mouse Model of the Progressive Hereditary Kidney Disease Alport Syndrome The Journal of Clinical Investigation. Mar, 2010 | Pubmed ID: 20197625 Blimp1-mediated Repression of Negative Regulators is Required for Osteoclast Differentiation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133620 Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of a GATA1 Protein Lacking the N-terminal Domain The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19854837 Autotaxin/lysophospholipase D-mediated Lysophosphatidic Acid Signaling is Required to Form Distinctive Large Lysosomes in the Visceral Endoderm Cells of the Mouse Yolk Sac The Journal of Biological Chemistry. Nov, 2009 | Pubmed ID: 19808661 Transcription Factor GATA-3 is Essential for Lens Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2009 | Pubmed ID: 19623612 Enhanced Humoral Immune Responses Against T-independent Antigens in Fc Alpha/muR-deficient Mice Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009 | Pubmed ID: 19549827 Selective Loss of GABA(B) Receptors in Orexin-producing Neurons Results in Disrupted Sleep/wakefulness Architecture Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19246384 Gene Expression Profile of the Third Pharyngeal Pouch Reveals Role of Mesenchymal MafB in Embryonic Thymus Development Blood. Mar, 2009 | Pubmed ID: 19164599 Aire Controls the Differentiation Program of Thymic Epithelial Cells in the Medulla for the Establishment of Self-tolerance The Journal of Experimental Medicine. Nov, 2008 | Pubmed ID: 19015306 Embryonic Stem Cells Derived from C57BL/6J and C57BL/6N Mice Comparative Medicine. Aug, 2008 | Pubmed ID: 18724776 Th1 and Type 1 Cytotoxic T Cells Dominate Responses in T-bet Overexpression Transgenic Mice That Develop Contact Dermatitis Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007 | Pubmed ID: 17182601 Characterization of GATA-1(+) Hemangioblastic Cells in the Mouse Embryo The EMBO Journal. Jan, 2007 | Pubmed ID: 17159898 MafB is Essential for Renal Development and F4/80 Expression in Macrophages Molecular and Cellular Biology. Aug, 2006 | Pubmed ID: 16847325 Overexpression of the Transcription Factor GATA-3 Enhances the Development of Pulmonary Fibrosis The American Journal of Pathology. Jul, 2006 | Pubmed ID: 16816364 Combinatorial Gata2 and Sca1 Expression Defines Hematopoietic Stem Cells in the Bone Marrow Niche Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16461905 EM703 Improves Bleomycin-induced Pulmonary Fibrosis in Mice by the Inhibition of TGF-beta Signaling in Lung Fibroblasts Respiratory Research. Jan, 2006 | Pubmed ID: 16438734 Uterine Sensitization-associated Gene-1 (USAG-1), a Novel BMP Antagonist Expressed in the Kidney, Accelerates Tubular Injury The Journal of Clinical Investigation. Jan, 2006 | Pubmed ID: 16341262 GATA Motifs Regulate Early Hematopoietic Lineage-specific Expression of the Gata2 Gene Molecular and Cellular Biology. Aug, 2005 | Pubmed ID: 16055713 MafA is a Key Regulator of Glucose-stimulated Insulin Secretion Molecular and Cellular Biology. Jun, 2005 | Pubmed ID: 15923615 The Distal Sequence Element of the Selenocysteine TRNA Gene is a Tissue-dependent Enhancer Essential for Mouse Embryogenesis Molecular and Cellular Biology. May, 2005 | Pubmed ID: 15831471 [Network of Transcription Factors for Biological Functions] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Dec, 2004 | Pubmed ID: 15669283 Leukemogenesis Caused by Incapacitated GATA-1 Function Molecular and Cellular Biology. Dec, 2004 | Pubmed ID: 15572684 Distinct Response to Dioxin in an Arylhydrocarbon Receptor (AHR)-humanized Mouse Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12730383 Functional Analysis of Basic Transcription Element Binding Protein by Gene Targeting Technology Molecular and Cellular Biology. Apr, 2003 | Pubmed ID: 12640131 HLF/HIF-2alpha is a Key Factor in Retinopathy of Prematurity in Association with Erythropoietin The EMBO Journal. Mar, 2003 | Pubmed ID: 12606578 Hemoprotein Bach1 Regulates Enhancer Availability of Heme Oxygenase-1 Gene The EMBO Journal. Oct, 2002 | Pubmed ID: 12356737 Essential and Instructive Roles of GATA Factors in Eosinophil Development The Journal of Experimental Medicine. Jun, 2002 | Pubmed ID: 12045236 In Vivo Requirements for GATA-1 Functional Domains During Primitive and Definitive Erythropoiesis The EMBO Journal. Sep, 2001 | Pubmed ID: 11566888 A GATA Box in the GATA-1 Gene Hematopoietic Enhancer is a Critical Element in the Network of GATA Factors and Sites That Regulate This Gene Molecular and Cellular Biology. Jan, 2000 | Pubmed ID: 10611250 GATA-1 Transcription is Controlled by Distinct Regulatory Mechanisms During Primitive and Definitive Erythropoiesis Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997 | Pubmed ID: 9114016 Starvation-induced Transcription Factor CREBH Negatively Governs Body Growth by Controlling GH Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. | Pubmed ID: 34042217 Impact of Spaceflight on the Murine Thymus and Mitigation by Exposure to Artificial Gravity During Spaceflight Scientific Reports. | Pubmed ID: 31882694 Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice Hepatology (Baltimore, Md.). | Pubmed ID: 31529722 Hyperlipidemia and Hepatitis in Liver-specific CREB3L3 Knockout Mice Generated Using a One-step CRISPR/Cas9 System Scientific Reports. | Pubmed ID: 27291420 Zygote micro-injectie voor het maken van gencassette knock-in en flox-allelen bij muizen Yoko Tanimoto*1, Natsuki Mikami*1,2, Miyuki Ishida1, Natsumi Iki1, Kanako Kato1, Fumihiro Sugiyama1, Satoru Takahashi1, Seiya Mizuno1 1Laboratory Animal Resource Center and Trans-Border Medical Research Center, University of Tsukuba, 2Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba JoVE 64161 발생학
Zygote micro-injectie voor het maken van gencassette knock-in en flox-allelen bij muizen Yoko Tanimoto*1, Natsuki Mikami*1,2, Miyuki Ishida1, Natsumi Iki1, Kanako Kato1, Fumihiro Sugiyama1, Satoru Takahashi1, Seiya Mizuno1 1Laboratory Animal Resource Center and Trans-Border Medical Research Center, University of Tsukuba, 2Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba JoVE 64161 발생학