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Immunology and Infection

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JoVE Journal Immunology and Infection
Cefoperazon behandlade musmodell av kliniskt relevanta
 
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Cefoperazon behandlade musmodell av kliniskt relevanta

Article DOI: 10.3791/54850-v • 06:51 min • December 10th, 2016
December 10th, 2016 •
1, 1, 2, 1
1Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, 2Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine

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Detta protokoll beskriver cefoperazon musmodell av Clostridium difficile-infektion (CDI) med en kliniskt relevant och genetiskt foglig stam, R20291. Betoning på klinisk övervakning sjukdom, C. difficile bakteriell uppräkning, toxin cytotoxicitet och histopatologiska förändringar under CDI i en musmodell beskrivs i protokollet.

Tags

Infektion , musmodell antibiotikum kolonisering cytotoxicitet histologi inflammation Vero-celler
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