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En liten djurmodell för Ex Vivo Normothermic lever Perfusion
 
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En liten djurmodell för Ex Vivo Normothermic lever Perfusion

Article DOI: 10.3791/57541-v • 08:32 min • June 27th, 2018
June 27th, 2018 •
1,2, 1, 1,2, 1,2, 1, 1, 3, 4, 2, 1,3, 1,2
1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, 4Department of Medicine, Ohio State University Wexner Medical Center

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Det saknas betydande lever givare och kriterier för levern har utökats. Normothermic ex vivo lever perfusion (NEVLP) har utvecklats för att utvärdera och ändra organfunktion. Denna studie visar en råtta modell av NEVLP och tester pegylerat-katalas, förmåga att minska levern bevarande skada.

Tags

Medicin fråga 136 Normothermic ex vivo lever perfusion NEVLP marginella organ utökade kriterier givare små djurmodell gnagare råtta
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