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JoVE Journal Neuroscience
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
 

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Article DOI: 10.3791/60296-v • 12:28 min • June 3rd, 2020
June 3rd, 2020 •
*1,4, *1, 1, 2, 1, 1, 1,4, 3, 3, 3, 5, 2,6, 7, 5, 8, 1,2,3
1Department of Neurology and Neuropathology, Golgi-Cenci Foundation, 2Laboratory of Neurobiology and Neurogenetic, Golgi-Cenci Foundation, 3Department of Neuropsychology and Social Sciences, Golgi-Cenci Foundation, 4Department of Rehabilitation, ASP Golgi-Redaelli Geriatric Hospital, 5Genomic and Post-Genomic Center, IRCCS Mondino Foundation, 6Department of Brain and Behavioral Sciences, University of Pavia, 7Department of Pathology, ASP Golgi-Redaelli Geriatric Hospital, 8Department of Neurological Science, IRCCS Mondino Foundation, University of Pavia
* These authors contributed equally

챕터

요약
Automatic Translation

This protocol describes a method to track individual brain-aging trajectories through a brain donation program and proper characterization of brains. Brain donors are involved in a long-term longitudinal study including serial multi-dimensional assessments. The protocol contains a detailed description of brain processing and an accurate diagnostic methodology.

Tags

Abbiategrasso Brain Bank Protocol Collecting Aging Brains Processing Aging Brains Characterizing Aging Brains Neurocognitive Disorder Brain Tissue Samples Accurate Diagnosis Neurodegenerative Mechanisms Brain Asymmetry Sampling Methodology Histologically Well-defined Tissues Deep Learning Multiple Pathologies Clinical Syndrome Neuropathological Findings Disease Pathogenesis Fresh Cutting Procedures Macro Section Management Trained Team Mammal Dexterity Visual Demonstration Thanatography Scalp Incision
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