Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Developmental Biology / Generation af en menneskelig iPSC-baseret…
JoVE Journal
Developmental Biology

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE Journal Developmental Biology
Generation af en menneskelig iPSC-baseret blod-hjerne barrierchip
 
Click here for the English version

Generation af en menneskelig iPSC-baseret blod-hjerne barrierchip

Article DOI: 10.3791/60925-v • 10:20 min • March 2nd, 2020
March 2nd, 2020 •
1,2,3, 4, 5,6, 4, 1,2,3
1The Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 2The Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, 3The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, 4The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 5Division of Micro and Nanosystems, KTH Royal Institute of Technology, 6AIMES, Department of Neuroscience, Karolinska Institutet

챕터

요약
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Blod - hjerne barrieren (BBB) er en multicellulær neurovaskulær enhed stramt regulere hjernen homøostase. Ved at kombinere menneskelige iPSCs og organ-on-chip teknologier, har vi genereret en personlig BBB chip, egnet til sygdom modellering og CNS narkotika penetrability forudsigelser. En detaljeret protokol er beskrevet for produktion og drift af BBB-chippen.

Tags

Udviklingsbiologi blodhjernebarrieren BBB mikrofluidic organ-on-chip OoC neurovaskulær enhed NVU iPSC iPS-celler astrocytter personlig medicin præcisionsmedicin
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter