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Journal / Medicine / Murine Precision-Cut Lever skiver som en Ex Vivo…
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Murine Precision-Cut Lever skiver som en Ex Vivo Model af leverbiologi
 
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Murine Precision-Cut Lever skiver som en Ex Vivo Model af leverbiologi

Article DOI: 10.3791/60992-v • 12:36 min • March 14th, 2020
March 14th, 2020 •
*1, *1, 2,3, 1,4,5, 6, 7, 8,9, 2,10, 1,4
1Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, 2School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, 3School of Veterinary and Life Sciences, Murdoch University, 4School of Medicine, The University of Queensland, 5Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, 6School of Medicine, Griffith University, 7School of Biological Sciences, Queen's University Belfast, 8Department of Gastroenterology & Hepatology, Fiona Stanley and Fremantle Hospital Group, 9School of Medical and Health Sciences, Edith Cowan University, 10Centre for Cell Therapy and Regenerative Medicine, School of Biomedical Sciences, University of Western Australia
* These authors contributed equally

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Denne protokol giver en enkel og pålidelig metode til produktion af levedygtige præcision-cut leverskiver fra mus. Ex vivo vævsprøver kan opretholdes under laboratorievæv kultur betingelser for flere dage, hvilket giver en fleksibel model til at undersøge leveren patobiologi.

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