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Ein Ex Vivo Choroid Sprouting Assay der ocular Microvascular Angiogenese
 
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Ein Ex Vivo Choroid Sprouting Assay der ocular Microvascular Angiogenese

Article DOI: 10.3791/61677-v • 06:10 min • August 6th, 2020
August 6th, 2020 •
1, 2, 1, 1, 1,3, 1
1Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 2Department of Clinical and Metabolic Genetics, Hospital for Sick Children, University of Toronto, 3Manton Center for Orphan Disease, Harvard Medical School, Boston Children's Hospital

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Dieses Protokoll stellt einen Aderhautkeim-Assay dar, ein Ex-vivo-Modell der mikrovaskulären Proliferation. Dieser Test kann verwendet werden, um Wege zu bewerten, die an sich vermehrenden aderatorischen Mikrogefäßen beteiligt sind, und medikamentöse Behandlungen mit Wildtyp und genetisch verändertem Mausgewebe zu bewerten.

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Biologie Ausgabe 162 Choroid-Sprossen-Assay Endothelzellen retinale pigmentepithel RPE Aderhautangiogenese choroidale Neovaskularisation altersbedingte Makuladegeneration AMD ex vivo
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