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JoVE Journal Neuroscience
Analyse multiplexée de l’expression génique rétinienne et de l’accessibilité de la chromatine à l’aide de scRNA-Seq et scATAC-Seq
 
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Analyse multiplexée de l’expression génique rétinienne et de l’accessibilité de la chromatine à l’aide de scRNA-Seq et scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Ici, les auteurs démontrent l’utilité de MULTI-seq pour le phénotypage et les scRNA-seq et scATAC-seq appariés ultérieurs dans la caractérisation des profils d’accessibilité transcriptomique et chromatine dans la rétine.

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Neurosciences Numéro 169 Développement Maladie scRNA-Seq scATAC-Seq MULTI-Seq multiplex Chromatine
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