Espansione del toolkit per l'imaging in vivo del trasporto assonale

Article DOI: 10.3791/63471-v • 09:24 min • December 23rd, 2021

December 23rd, 2021 •

Andrew P. Tosolini^1,2, David Villarroel-Campos^1,2,3, Giampietro Schiavo^1,2,3, James N. Sleigh^1,2,3

¹Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, ²UCL Queen Square Motor Neuron Disease Centre, University College London, ³UK Dementia Research Institute, University College London

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Utilizzando topi fluorescenti transgenici, vengono descritti protocolli dettagliati per valutare il trasporto assonale in vivo di endosomi e mitocondri di segnalazione all'interno di assoni motori e sensoriali del nervo sciatico intatto in animali vivi.

Espansione del toolkit per l'imaging in vivo del trasporto assonale

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