Ampliación del kit de herramientas para imágenes in vivo del transporte axonal

Article DOI: 10.3791/63471-v • 09:24 min • December 23rd, 2021

December 23rd, 2021 •

Andrew P. Tosolini^1,2, David Villarroel-Campos^1,2,3, Giampietro Schiavo^1,2,3, James N. Sleigh^1,2,3

¹Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, ²UCL Queen Square Motor Neuron Disease Centre, University College London, ³UK Dementia Research Institute, University College London

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Utilizando ratones fluorescentes transgénicos, se describen protocolos detallados para evaluar el transporte axonal in vivo de endosomas de señalización y mitocondrias dentro de los axones motores y sensoriales del nervio ciático intacto en animales vivos.

Ampliación del kit de herramientas para imágenes in vivo del transporte axonal

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