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Journal / Biochemistry / 使用场效应生物传感技术探索分子伴侣Hsp90与其客户蛋白激酶Cdc37之间的生物分子相互作用…
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Biochemistry

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JoVE Journal Biochemistry
使用场效应生物传感技术探索分子伴侣Hsp90与其客户蛋白激酶Cdc37之间的生物分子相互作用
 
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使用场效应生物传感技术探索分子伴侣Hsp90与其客户蛋白激酶Cdc37之间的生物分子相互作用

Article DOI: 10.3791/63495-v • 09:39 min • March 31st, 2022
March 31st, 2022 •
*1, *1, 2, 2, 1
1The Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, 2Asian Liver Center, Department of Surgery, Stanford University School of Medicine
* These authors contributed equally

챕터

요약
Automatic Translation

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场效应生物传感（FEB）是一种用于检测生物分子相互作用的无标记技术。它测量通过石墨烯生物传感器的电流，结合目标被固定到该传感器。FEB技术用于评估Hsp90和Cdc37之间的生物分子相互作用，并检测到两种蛋白质之间的强相互作用。

Tags

生物化学，第181期，细胞分裂周期37，Cdc37，热休克蛋白90，Hsp90，蛋白激酶，石墨烯生物传感器，场效应生物传感，癌症，生物分子相互作用
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