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Establishment of Central Cord Syndrome Model in C57BL/6J Mouse
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Neuroscience
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JoVE Journal Neuroscience
Establishment of Central Cord Syndrome Model in C57BL/6J Mouse

Establishment of Central Cord Syndrome Model in C57BL/6J Mouse

DOI:
10.3791/65028-v

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06:36 min

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September 08, 2023

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, ,
1Department of Orthopaedics,Qilu Hospital of Shandong University, 2Department of Orthopaedics,Tianjin Medical University General Hospital

Chapters

  • 00:00Introduction
  • 00:42C6 Laminectomy and Spinal Cord Exposure
  • 03:08Cervical Spinal Cord Compression Injury
  • 04:25Results: Histological Analysis and MRI of Murine Spinal Cord Post the Spinal Cord Injury
  • 06:08Conclusion

Summary

Automatic Translation

Automatic Translation

The present protocol simulating central cord syndrome (CCS) in mice has improved repeatability and minimized operation damage to the experimental animals, avoiding disrupting the anatomical structure excessively. The strategy in this study is advantageous because it allows for research into injury mechanisms by producing consistent results.

Tags

Keywords: Central Cord SyndromeAnimal ModelC57BL/6J MouseSpinal Cord InjurySurgical ProcedureVertebraSpinal CordLaminaLaminectomyVertebral Stabilizer

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