A.L.T.O. Nascimento Laboratório de Desenvolvimento de Vacinas Instituto Butantan Biography Publications Institution JoVE Articles A.L.T.O. Nascimento has not added a biography. If you are A.L.T.O. Nascimento and would like to personalize this page please email our Author Liaison for assistance. Publications The Leptospira Interrogans LIC10774 is a Multifunctional Surface Protein That Binds Calcium and Interacts with Host Components Microbiological Research. May, 2020 | Pubmed ID: 32247916 Identification of a Novel Protein in the Genome Sequences of Leptospira Interrogans with the Ability to Interact with Host's Components Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. Feb, 2020 | Pubmed ID: 30713004 Adjuvanted Leptospiral Vaccines: Challenges and Future Development of New Leptospirosis Vaccines Vaccine. 07, 2019 | Pubmed ID: 31186193 Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules Among Pathogenic, Intermediate, and Non-Pathogenic Microorganisms. Feb, 2019 | Pubmed ID: 30791633 Gene Silencing Based on RNA-guided Catalytically Inactive Cas9 (dCas9): a New Tool for Genetic Engineering in Leptospira Scientific Reports. 02, 2019 | Pubmed ID: 30755626 Characterization of a Novel Protein of Leptospira Interrogans Exhibiting Plasminogen, Vitronectin and Complement Binding Properties International Journal of Medical Microbiology : IJMM. Mar, 2019 | Pubmed ID: 30638770 Proteomics As a Tool to Understand Leptospira Physiology and Virulence: Recent Advances, Challenges and Clinical Implications Journal of Proteomics. 05, 2018 | Pubmed ID: 29501847 Binding of Human Plasminogen by the Lipoprotein LipL46 of Leptospira Interrogans Molecular and Cellular Probes. 02, 2018 | Pubmed ID: 29108931 The Role of Lsa23 to Mediate the Interaction of Leptospira Interrogans with the Terminal Complement Components Pathway Microbial Pathogenesis. Nov, 2017 | Pubmed ID: 28963011 Multifunctional and Redundant Roles of Leptospira Interrogans Proteins in Bacterial-Adhesion and Fibrin Clotting Inhibition International Journal of Medical Microbiology : IJMM. Sep, 2017 | Pubmed ID: 28600123 Immune Response and Protective Profile Elicited by a Multi-epitope Chimeric Protein Derived from Leptospira Interrogans International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Apr, 2017 | Pubmed ID: 28161462 Mammalian Cell Entry (Mce) Protein of Leptospira Interrogans Binds Extracellular Matrix Components, Plasminogen and β2 Integrin Microbiology and Immunology. Sep, 2016 | Pubmed ID: 27468683 Evaluation of Two Novel Leptospiral Proteins for Their Interaction with Human Host Components Pathogens and Disease. 07, 2016 | Pubmed ID: 27129366 Leptospira Spp.: Novel Insights into Host-pathogen Interactions Veterinary Immunology and Immunopathology. Aug, 2016 | Pubmed ID: 26727033 The Recombinant LIC10508 is a Plasma Fibronectin, Plasminogen, Fibrinogen and C4BP-binding Protein of Leptospira Interrogans Pathogens and Disease. Mar, 2016 | Pubmed ID: 26657108 Leptospira Interrogans Reduces Fibrin Clot Formation by Modulating Human Thrombin Activity Via Exosite I Pathogens and Disease. Jun, 2015 | Pubmed ID: 25834144 Novel Leptospira Interrogans Protein Lsa32 is Expressed During Infection and Binds Laminin and Plasminogen Microbiology (Reading, England). Apr, 2015 | Pubmed ID: 25627443 Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira L. G. V. Fernandes1,2, R. L. Hornsby1, A.L.T.O. Nascimento*2, J. E. Nally*1 1Infectious Bacterial Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 2Laboratório de Desenvolvimento de Vacinas, Instituto Butantan JoVE 62631 Genética
Application of CRISPR Interference (CRISPRi) for Gene Silencing in Pathogenic Species of Leptospira L. G. V. Fernandes1,2, R. L. Hornsby1, A.L.T.O. Nascimento*2, J. E. Nally*1 1Infectious Bacterial Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, 2Laboratório de Desenvolvimento de Vacinas, Instituto Butantan JoVE 62631 Genética