Alison L. Allan London Regional Cancer Program Biography Publications Institution JoVE Articles Alison L. Allan has not added a biography. If you are Alison L. Allan and would like to personalize this page please email our Author Liaison for assistance. Publications Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment Cancers. Jan, 2020 | Pubmed ID: 31936750 Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response Cancers. Aug, 2019 | Pubmed ID: 31450577 On-Chip Preparation of Amphiphilic Nanomicelles-in-Sodium Alginate Spheroids As a Novel Platform Against Triple-Negative Human Breast Cancer Cells: Fabrication, Study of Microfluidics Flow Hydrodynamics and Proof of Concept for Anticancer and Drug Delivery Applications Journal of Pharmaceutical Sciences. 11, 2019 | Pubmed ID: 31351864 Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives International Journal of Molecular Sciences. May, 2019 | Pubmed ID: 31071959 A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205 Clinical Genitourinary Cancer. 06, 2019 | Pubmed ID: 31056399 Magnetically Guided Self-Assembled Protein Micelles for Enhanced Delivery of Dasatinib to Human Triple-Negative Breast Cancer Cells Journal of Pharmaceutical Sciences. 05, 2019 | Pubmed ID: 30528944 Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells As a Predictive Biomarker for Castration-Resistant Prostate Cancer JAMA Oncology. 09, 2018 | Pubmed ID: 29955787 Circulating Tumor Cell Analysis in Preclinical Mouse Models of Metastasis Diagnostics (Basel, Switzerland). Apr, 2018 | Pubmed ID: 29710776 Self-assembled Amphiphilic Zein-lactoferrin Micelles for Tumor Targeted Co-delivery of Rapamycin and Wogonin to Breast Cancer European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Jul, 2018 | Pubmed ID: 29689288 Circulating Tumor Cells and Implications of the Epithelial-to-Mesenchymal Transition Advances in Clinical Chemistry. 2018 | Pubmed ID: 29304900 Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells International Journal of Molecular Sciences. Sep, 2017 | Pubmed ID: 28937653 Soluble Bone-derived Osteopontin Promotes Migration and Stem-like Behavior of Breast Cancer Cells PloS One. 2017 | Pubmed ID: 28498874 Epithelial-to-mesenchymal Transition Leads to Disease-stage Differences in Circulating Tumor Cell Detection and Metastasis in Pre-clinical Models of Prostate Cancer Oncotarget. Nov, 2016 | Pubmed ID: 27764810 Circulating Tumor Cells (CTC) and Cell-Free DNA (cfDNA) Workshop 2016: Scientific Opportunities and Logistics for Cancer Clinical Trial Incorporation International Journal of Molecular Sciences. Sep, 2016 | Pubmed ID: 27618023 Central, But Not Peripheral, Circulating Tumor Cells Are Prognostic in Patients Undergoing Resection of Colorectal Cancer Liver Metastases Annals of Surgical Oncology. Jul, 2016 | Pubmed ID: 26714949 Aldehyde Dehydrogenase As a Marker and Functional Mediator of Metastasis in Solid Tumors Clinical & Experimental Metastasis. Jan, 2016 | Pubmed ID: 26445849 Lung-derived Factors Mediate Breast Cancer Cell Migration Through CD44 Receptor-ligand Interactions in a Novel Ex Vivo System for Analysis of Organ-specific Soluble Proteins Neoplasia (New York, N.Y.). Feb, 2014 | Pubmed ID: 24709425 Recent Advances in the Molecular Characterization of Circulating Tumor Cells Cancers. 2014 | Pubmed ID: 24633084 User-defined Protein Marker Assay Development for Characterization of Circulating Tumor Cells Using the CellSearch® System Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2012 | Pubmed ID: 22899576 The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance Between the "Seed" and the "Soil"? International Journal of Breast Cancer. 2012 | Pubmed ID: 22295241 Image Cytometry Analysis of Circulating Tumor Cells Methods in Cell Biology. 2011 | Pubmed ID: 21704842 Migratory Strategies of Normal and Malignant Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21618081 Deletion of the Thrombin Cleavage Domain of Osteopontin Mediates Breast Cancer Cell Adhesion, Proteolytic Activity, Tumorgenicity, and Metastasis BMC Cancer. 2011 | Pubmed ID: 21247495 Circulating Tumor Cell Analysis: Technical and Statistical Considerations for Application to the Clinic Journal of Oncology. 2010 | Pubmed ID: 20049168 Lymphatic Metastasis of Breast Cancer Cells is Associated with Differential Gene Expression Profiles That Predict Cancer Stem Cell-like Properties and the Ability to Survive, Establish and Grow in a Foreign Environment International Journal of Oncology. Aug, 2009 | Pubmed ID: 19578743 Characterization of Tumor Cell Dissemination Patterns in Preclinical Models of Cancer Metastasis Using Flow Cytometry and Laser Scanning Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2009 | Pubmed ID: 18855920 High Aldehyde Dehydrogenase and Expression of Cancer Stem Cell Markers Selects for Breast Cancer Cells with Enhanced Malignant and Metastatic Ability Journal of Cellular and Molecular Medicine. Aug, 2009 | Pubmed ID: 18681906 Downregulation of Osteopontin Contributes to Metastasis Suppression by Breast Cancer Metastasis Suppressor 1 International Journal of Cancer. Journal International Du Cancer. Aug, 2008 | Pubmed ID: 18470911 The Thrombin Inhibitor Argatroban Reduces Breast Cancer Malignancy and Metastasis Via Osteopontin-dependent and Osteopontin-independent Mechanisms Breast Cancer Research and Treatment. Nov, 2008 | Pubmed ID: 18097747 Osteopontin Overexpression in Breast Cancer: Knowledge Gained and Possible Implications for Clinical Management Journal of Cellular Biochemistry. Nov, 2007 | Pubmed ID: 17721886 Tumor Dormancy and Cancer Stem Cells: Implications for the Biology and Treatment of Breast Cancer Metastasis Breast Disease. 2006-2007 | Pubmed ID: 17473368 Tumor Dormancy and the Role of Metastasis Suppressor Genes in Regulating Ectopic Growth Future Oncology (London, England). Oct, 2006 | Pubmed ID: 17026454 Role of the Integrin-binding Protein Osteopontin in Lymphatic Metastasis of Breast Cancer The American Journal of Pathology. Jul, 2006 | Pubmed ID: 16816376 A New Model for Lymphatic Metastasis: Development of a Variant of the MDA-MB-468 Human Breast Cancer Cell Line That Aggressively Metastasizes to Lymph Nodes Clinical & Experimental Metastasis. 2005 | Pubmed ID: 16170671 Detection and Quantification of Circulating Tumor Cells in Mouse Models of Human Breast Cancer Using Immunomagnetic Enrichment and Multiparameter Flow Cytometry Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2005 | Pubmed ID: 15810015 Isolement et évaluation fonctionnelle des cellules souches du cancer du sein humain à partir d’échantillons de cellules et de tissus Vasudeva Bhat1,2, Cory Lefebvre1,2, David Goodale1, Mauricio Rodriguez-Torres1,2, Alison L. Allan1,2,3,4 1London Regional Cancer Program, 2Department of Anatomy & Cell Biology, Western University, 3Department of Oncology, Western University, 4Lawson Health Research Institute JoVE 61775 Pesquisa do câncer Adaptation des semi-automatique de circulation des cellules tumorales (CTC) Essais pour les applications cliniques et précliniques de recherche Lori E. Lowes1,2, Benjamin D. Hedley3, Michael Keeney3,4, Alison L. Allan1,2,4,5 1London Regional Cancer Program, London Health Sciences Centre, 2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, 3Special Hematology/Flow Cytometry, London Health Sciences Centre, 4Lawson Health Research Institute, 5Department of Oncology, Western University JoVE 51248 Medicina
Isolement et évaluation fonctionnelle des cellules souches du cancer du sein humain à partir d’échantillons de cellules et de tissus Vasudeva Bhat1,2, Cory Lefebvre1,2, David Goodale1, Mauricio Rodriguez-Torres1,2, Alison L. Allan1,2,3,4 1London Regional Cancer Program, 2Department of Anatomy & Cell Biology, Western University, 3Department of Oncology, Western University, 4Lawson Health Research Institute JoVE 61775 Pesquisa do câncer
Adaptation des semi-automatique de circulation des cellules tumorales (CTC) Essais pour les applications cliniques et précliniques de recherche Lori E. Lowes1,2, Benjamin D. Hedley3, Michael Keeney3,4, Alison L. Allan1,2,4,5 1London Regional Cancer Program, London Health Sciences Centre, 2Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, 3Special Hematology/Flow Cytometry, London Health Sciences Centre, 4Lawson Health Research Institute, 5Department of Oncology, Western University JoVE 51248 Medicina