Andrew M. Lowy Department of Surgery University of California Biography Publications Institution JoVE Articles Andrew M. Lowy has not added a biography. If you are Andrew M. Lowy and would like to personalize this page please email our Author Liaison for assistance. Publications Laparoscopic Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: a Prospective Clinical Trial and Comparative Analysis Surgical Endoscopy. Dec, 2022 | Pubmed ID: 36477643 ASO Visual Abstract: Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC? Annals of Surgical Oncology. Nov, 2022 | Pubmed ID: 36369408 Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC? Annals of Surgical Oncology. Oct, 2022 | Pubmed ID: 36305990 Collagenolysis-dependent DDR1 Signalling Dictates Pancreatic Cancer Outcome Nature. Oct, 2022 | Pubmed ID: 36198801 Alvimopan for Enhanced Gastrointestinal Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Randomized Controlled Trial Journal of the American College of Surgeons. Nov, 2022 | Pubmed ID: 36102565 An Ex Vivo Organotypic Culture Platform for Functional Interrogation of Human Appendiceal Cancer Reveals a Prominent and Heterogenous Immunological Landscape Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2022 | Pubmed ID: 36067351 Early-stage Multi-cancer Detection Using an Extracellular Vesicle Protein-based Blood Test Communications Medicine. 2022 | Pubmed ID: 35603292 The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies Cancers. Apr, 2022 | Pubmed ID: 35454943 Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft In Vivo (Athens, Greece). 2022 | Pubmed ID: 34972700 Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies Gut and Liver. Jul, 2022 | Pubmed ID: 34916338 Author Correction: Targeting LIF-mediated Paracrine Interaction for Pancreatic Cancer Therapy and Monitoring Nature. Dec, 2021 | Pubmed ID: 34848876 Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond Cancers. Oct, 2021 | Pubmed ID: 34638476 Randomized Phase II Study of PARP Inhibitor ABT-888 (Veliparib) with Modified FOLFIRI Versus FOLFIRI As Second-line Treatment of Metastatic Pancreatic Cancer: SWOG S1513 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2021 | Pubmed ID: 34580114 Tri-modal Management of Primary Small Cell Carcinoma of the Pancreas (SCCP): a Rare Neuroendocrine Carcinoma (NEC) BMC Gastroenterology. Sep, 2021 | Pubmed ID: 34479480 Ki67 Does Not Predict Recurrence for Low-grade Appendiceal Mucinous Neoplasms with Peritoneal Dissemination After Cytoreductive Surgery and HIPEC Human Pathology. Jul, 2021 | Pubmed ID: 33905776 Tumor-penetrating Therapy for β5 Integrin-rich Pancreas Cancer Nature Communications. Mar, 2021 | Pubmed ID: 33750829 Cancer Cells Escape Autophagy Inhibition Via NRF2-induced Macropinocytosis Cancer Cell. May, 2021 | Pubmed ID: 33740421 Clinical Data Prediction Model to Identify Patients With Early-Stage Pancreatic Cancer JCO Clinical Cancer Informatics. Mar, 2021 | Pubmed ID: 33739856 Predictors and Significance of Histologic Response to Neoadjuvant Therapy for Gastric Cancer Journal of Surgical Oncology. May, 2021 | Pubmed ID: 33735448 Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness Cancer Discovery. Jul, 2021 | Pubmed ID: 33653692 Phase I Trial of Stereotactic Body Radiation Therapy Dose Escalation in Pancreatic Cancer International Journal of Radiation Oncology, Biology, Physics. Jul, 2021 | Pubmed ID: 33571625 Efficacy of Perioperative Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Phase 2 Randomized Clinical Trial JAMA Oncology. Mar, 2021 | Pubmed ID: 33475684 A MET Targeting Antibody-Drug Conjugate Overcomes Gemcitabine Resistance in Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2021 | Pubmed ID: 33451980 A Multi-institutional Study of Peritoneal Recurrence Following Resection of Low-grade Appendiceal Mucinous Neoplasms Annals of Surgical Oncology. Aug, 2021 | Pubmed ID: 33415564 Preoperative Bevacizumab Does Not Increase Complications Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy PloS One. 2020 | Pubmed ID: 33270763 Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases Annals of Surgical Oncology. Sep, 2020 | Pubmed ID: 32767050 Surgical Outcome Results From SWOG S1505: A Randomized Clinical Trial of MFOLFIRINOX Versus Gemcitabine/Nab-paclitaxel for Perioperative Treatment of Resectable Pancreatic Ductal Adenocarcinoma Annals of Surgery. Sep, 2020 | Pubmed ID: 32740235 Institutional Variation in Recovery After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Opportunity for Enhanced Recovery Pathways Journal of Surgical Oncology. Oct, 2020 | Pubmed ID: 32627199 Adherence with Operative Standards in the Treatment of Gastric Cancer in the United States Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. May, 2020 | Pubmed ID: 31745679 Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability Molecular Cancer Therapeutics. Jan, 2020 | Pubmed ID: 31597712 Optimal Surveillance Frequency After CRS/HIPEC for Appendiceal and Colorectal Neoplasms: A Multi-institutional Analysis of the US HIPEC Collaborative Annals of Surgical Oncology. Jan, 2020 | Pubmed ID: 31243668 Detection and Quantification of GPCR MRNA: An Assessment and Implications of Data from High-Content Methods ACS Omega. Oct, 2019 | Pubmed ID: 31646252 Association of an Acute Pain Service with Postoperative Outcomes Following Pancreaticoduodenectomy Journal of Perioperative Practice. Oct, 2019 | Pubmed ID: 31524066 Obstruction-Free Survival Following Operative Intervention for Malignant Bowel Obstruction in Appendiceal Cancer Annals of Surgical Oncology. Oct, 2019 | Pubmed ID: 31190209 Incidence, Risk Factors, and Prevention Strategies for Venous Thromboembolism After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Annals of Surgical Oncology. Jul, 2019 | Pubmed ID: 31065960 Primary Tumor Sidedness is Predictive of Survival in Colon Cancer Patients Treated with Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy: A US HIPEC Collaborative Study Annals of Surgical Oncology. Jul, 2019 | Pubmed ID: 31016486 Targeting LIF-mediated Paracrine Interaction for Pancreatic Cancer Therapy and Monitoring Nature. 05, 2019 | Pubmed ID: 30996350 MST1R Kinase Accelerates Pancreatic Cancer Progression Via Effects on Both Epithelial Cells and Macrophages Oncogene. 07, 2019 | Pubmed ID: 30967626 A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma Cell. Apr, 2019 | Pubmed ID: 30955884 Inhibition of Invasive Pancreatic Cancer: Restoring Cell Apoptosis by Activating Mitochondrial P53 American Journal of Cancer Research. 2019 | Pubmed ID: 30906636 Exosomes from Pancreatic Juice: A Step Closer to the Holy Grail? Annals of Surgical Oncology. Jul, 2019 | Pubmed ID: 30820788 Does Primary Tumor Side Matter in Patients with Metastatic Colon Cancer Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy? Annals of Surgical Oncology. May, 2019 | Pubmed ID: 30815802 E47 Governs the MYC-CDKN1B/p27-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type P53 Cellular and Molecular Gastroenterology and Hepatology. 2018 | Pubmed ID: 30003124 Preoperative Circulating Tumor DNA in Patients with Peritoneal Carcinomatosis is an Independent Predictor of Progression-Free Survival Annals of Surgical Oncology. Aug, 2018 | Pubmed ID: 29948422 GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets Frontiers in Pharmacology. 2018 | Pubmed ID: 29872392 Cirrhosis is Not a Contraindication to Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Highly Selected Patients World Journal of Surgical Oncology. Apr, 2018 | Pubmed ID: 29699564 Histologic Predictors of Recurrence in Mucinous Appendiceal Tumors with Peritoneal Dissemination After HIPEC Annals of Surgical Oncology. Mar, 2018 | Pubmed ID: 29282599 GPR68, a Proton-sensing GPCR, Mediates Interaction of Cancer-associated Fibroblasts and Cancer Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2018 | Pubmed ID: 29092903 Factors Associated with 60-Day Readmission Following Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy Annals of Surgical Oncology. Jan, 2018 | Pubmed ID: 29090402 An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204) Oncology. 2018 | Pubmed ID: 29040974 Safety and Outcome Measures of First-in-Human Intraperitoneal α Radioimmunotherapy With 212Pb-TCMC-Trastuzumab American Journal of Clinical Oncology. Jul, 2018 | Pubmed ID: 27906723 Reprogramming Pancreatic Stellate Cells Via P53 Activation: A Putative Target for Pancreatic Cancer Therapy PloS One. 2017 | Pubmed ID: 29211796 Molecular Pathways: Targeting the Microenvironment of Liver Metastases Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2017 | Pubmed ID: 28615370 Overinterpretation is Common in Pathological Diagnosis of Appendix Cancer During Patient Referral for Oncologic Care PloS One. 2017 | Pubmed ID: 28591173 Hyaluronan-binding Peptide for Targeting Peritoneal Carcinomatosis Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. May, 2017 | Pubmed ID: 28468593 Effect of Selumetinib and MK-2206 Vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy: SWOG S1115 Study Randomized Clinical Trial JAMA Oncology. Apr, 2017 | Pubmed ID: 27978579 Characterization of RON Protein Isoforms in Pancreatic Cancer: Implications for Biology and Therapeutics Oncotarget. Jul, 2016 | Pubmed ID: 27323855 Image-based Detection and Targeting of Therapy Resistance in Pancreatic Adenocarcinoma Nature. 06, 2016 | Pubmed ID: 27281208 Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101 JAMA Surgery. Aug, 2016 | Pubmed ID: 27275632 Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression Cancer Discovery. Aug, 2016 | Pubmed ID: 27179037 Urokinase-controlled Tumor Penetrating Peptide Journal of Controlled Release : Official Journal of the Controlled Release Society. 06, 2016 | Pubmed ID: 27106816 FRAX597, a PAK1 Inhibitor, Synergistically Reduces Pancreatic Cancer Growth when Combined with Gemcitabine BMC Cancer. Jan, 2016 | Pubmed ID: 26774265 A Novel Tool for Predicting Major Complications After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy Annals of Surgical Oncology. May, 2016 | Pubmed ID: 26678406 Laparoscopy is Safe and Accurate to Evaluate Peritoneal Surface Metastasis Prior to Cytoreductive Surgery Annals of Surgical Oncology. May, 2016 | Pubmed ID: 26542584 A Novel Protein Isoform of the RON Tyrosine Kinase Receptor Transforms Human Pancreatic Duct Epithelial Cells Oncogene. Jun, 2016 | Pubmed ID: 26477314 A Tumor-penetrating Peptide Enhances Circulation-independent Targeting of Peritoneal Carcinomatosis Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2015 | Pubmed ID: 26071630 SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2015 | Pubmed ID: 25964250 Approach to Patients with Pancreatic Cancer Without Detectable Metastases Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2015 | Pubmed ID: 25918279 BAP1 Mutation is a Frequent Somatic Event in Peritoneal Malignant Mesothelioma Journal of Translational Medicine. Apr, 2015 | Pubmed ID: 25889843 Tumor Radiosensitization by Monomethyl Auristatin E: Mechanism of Action and Targeted Delivery Cancer Research. Apr, 2015 | Pubmed ID: 25681274 Laparoscopic Evacuation of Mucinous Ascites for Palliation of Pseudomyxoma Peritonei Annals of Surgical Oncology. May, 2015 | Pubmed ID: 25395145 Tumor-penetrating IRGD Peptide Inhibits Metastasis Molecular Cancer Therapeutics. Jan, 2015 | Pubmed ID: 25392370 Predictors of Progression in High-grade Appendiceal or Colorectal Peritoneal Carcinomatosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Annals of Surgical Oncology. May, 2015 | Pubmed ID: 25145504 Single-incision Laparoscopic Surgery Through an Ostomy Site: a Natural Approach by an Unnatural Orifice Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. Feb, 2015 | Pubmed ID: 24743670 Enteral Stenting for Gastric Outlet Obstruction and Afferent Limb Syndrome Following Pancreaticoduodenectomy Annals of Gastroenterology. 2014 | Pubmed ID: 25332208 A Next-generation Dual-recombinase System for Time- and Host-specific Targeting of Pancreatic Cancer Nature Medicine. Nov, 2014 | Pubmed ID: 25326799 A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer Cancer Research. Nov, 2014 | Pubmed ID: 25261239 Correction: Genome-wide Mutational Landscape of Mucinous Carcinomatosis Peritonei of Appendiceal Origin Genome Medicine. 2014 | Pubmed ID: 25228923 Long-term Outcomes After Total Pancreatectomy and Islet Cell Autotransplantation: is It a Durable Operation? Annals of Surgery. Oct, 2014 | Pubmed ID: 25203883 Borderline Resectable Pancreatic Cancer: Definitions and Management World Journal of Gastroenterology. Aug, 2014 | Pubmed ID: 25152577 Dual Blockade of Epidermal Growth Factor Receptor and Insulin-like Growth Factor Receptor-1 Signaling in Metastatic Pancreatic Cancer: Phase Ib and Randomized Phase II Trial of Gemcitabine, Erlotinib, and Cixutumumab Versus Gemcitabine Plus Erlotinib (SWOG S0727) Cancer. Oct, 2014 | Pubmed ID: 25041791 Genome-wide Mutational Landscape of Mucinous Carcinomatosis Peritonei of Appendiceal Origin Genome Medicine. 2014 | Pubmed ID: 24944587 An Integrin β₃-KRAS-RalB Complex Drives Tumour Stemness and Resistance to EGFR Inhibition Nature Cell Biology. May, 2014 | Pubmed ID: 24747441 The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies Pancreas. Mar, 2014 | Pubmed ID: 24518495 Generation of Orthotopic Patient-derived Xenografts from Gastrointestinal Stromal Tumor Journal of Translational Medicine. Feb, 2014 | Pubmed ID: 24507750 Improved Perioperative Outcomes with Minimally Invasive Distal Pancreatectomy: Results from a Population-based Analysis JAMA Surgery. Mar, 2014 | Pubmed ID: 24402232 PI3Kα Activates Integrin α4β1 to Establish a Metastatic Niche in Lymph Nodes Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23671068 A Dual-color Genetically Engineered Mouse Model for Multispectral Imaging of the Pancreatic Microenvironment Pancreas. Aug, 2013 | Pubmed ID: 23648841 Therapeutic Advances in Pancreatic Cancer Gastroenterology. Jun, 2013 | Pubmed ID: 23622141 Borderline Resectable Pancreatic Cancer: Need for Standardization and Methods for Optimal Clinical Trial Design Annals of Surgical Oncology. Aug, 2013 | Pubmed ID: 23435609 Changing the Way We Do Business: Recommendations to Accelerate Biomarker Development in Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2013 | Pubmed ID: 23344262 Chemokine CXCL12 Activates Dual CXCR4 and CXCR7-mediated Signaling Pathways in Pancreatic Cancer Cells Journal of Translational Medicine. Apr, 2012 | Pubmed ID: 22472349 The RON-receptor Regulates Pancreatic Cancer Cell Migration Through Phosphorylation-dependent Breakdown of the Hemidesmosome International Journal of Cancer. Oct, 2012 | Pubmed ID: 22275185 Disruption of P16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in Vivo Oncotarget. Nov, 2011 | Pubmed ID: 22113502 IGF1-R Signals Through the RON Receptor to Mediate Pancreatic Cancer Cell Migration Carcinogenesis. Aug, 2011 | Pubmed ID: 21565828 免疫小鼠宿主中创胰腺癌原位模型的发展。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2010 | Pubmed ID: 20534740 罗恩酪氨酸激酶受体调节血管内皮生长因子在胰腺癌细胞中的生产。 Pancreas. Apr, 2010 | Pubmed ID: 20358644 Cystic Neoplasms of the Pancreas Surgical Oncology Clinics of North America. Apr, 2010 | Pubmed ID: 20159515 Pancreatic Cancer: Preface Surgical Oncology Clinics of North America. Apr, 2010 | Pubmed ID: 20159512 沉默的 RON 受体信号转导促进胰腺癌细胞凋亡和吉西他滨敏感性。 Cancer Research. Feb, 2010 | Pubmed ID: 20103639 Case Report: Focal Nesidioblastosis ("nesidioblastoma") in an Adult Human Pathology. Mar, 2010 | Pubmed ID: 20004945 Beyond the Ivory Tower: Outcomes Following Surgery for Ampullary Cancer Annals of Surgical Oncology. Jul, 2008 | Pubmed ID: 18425553 Neoadjuvant Therapy for Pancreatic Cancer Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Sep, 2008 | Pubmed ID: 18259825 Incidence, Natural History, and Patterns of Locoregional Recurrence in Gastric Cancer Patients Treated with Preoperative Chemoradiotherapy International Journal of Radiation Oncology, Biology, Physics. Jul, 2008 | Pubmed ID: 18164837 来自切除人肿瘤标本的 离体 器官型腹膜假粘液瘤肿瘤切片的培养和成像 Jonathan Weitz1, Kevin Christian Montecillo Gulay1, Tatiana Hurtado de Mendoza1, Herve Tiriac1, Joel Baumgartner1, Kaitlyn Kelly1, Jula Veerapong1, Andrew M. Lowy1 1Department of Surgery, University of California JoVE 64620 Pesquisa do câncer
来自切除人肿瘤标本的 离体 器官型腹膜假粘液瘤肿瘤切片的培养和成像 Jonathan Weitz1, Kevin Christian Montecillo Gulay1, Tatiana Hurtado de Mendoza1, Herve Tiriac1, Joel Baumgartner1, Kaitlyn Kelly1, Jula Veerapong1, Andrew M. Lowy1 1Department of Surgery, University of California JoVE 64620 Pesquisa do câncer