Aras Kadioglu Department of Clinical Infection Microbiology & Immunology, Institute of Infection & Global Health University of Liverpool Biography Publications Institution JoVE Articles Aras Kadioglu has not added a biography. If you are Aras Kadioglu and would like to personalize this page please email our Author Liaison for assistance. Publications Controlled Human Infection and Re-Challenge with Streptococcus Pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults American Journal of Respiratory and Critical Care Medicine. Jan, 2013 | Pubmed ID: 23370916 Nasopharyngeal Carriage with Streptococcus Pneumoniae Augments the Immunizing Effect of Pneumolysin Toxoid B The Journal of Allergy and Clinical Immunology. Dec, 2012 | Pubmed ID: 23260752 The Lectin Pathway of Complement Activation is a Critical Component of the Innate Immune Response to Pneumococcal Infection PLoS Pathogens. 2012 | Pubmed ID: 22792067 Nicotinamide Nucleotide Transhydrogenase (NNT) Acts As a Novel Modulator of Macrophage Inflammatory Responses FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2012 | Pubmed ID: 22593545 T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice PLoS Pathogens. 2012 | Pubmed ID: 22563306 P4-mediated Antibody Therapy in an Acute Model of Invasive Pneumococcal Disease The Journal of Infectious Diseases. May, 2012 | Pubmed ID: 22457294 Capsule Type of Streptococcus Pneumoniae Determines Growth Phenotype PLoS Pathogens. 2012 | Pubmed ID: 22412375 Persistence of Pneumolysin in the Cerebrospinal Fluid of Patients with Pneumococcal Meningitis is Associated with Mortality Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Mar, 2012 | Pubmed ID: 22238165 Absence of the Lectin Activation Pathway of Complement Does Not Increase Susceptibility to Pseudomonas Aeruginosa Infections Immunobiology. Feb, 2012 | Pubmed ID: 22070931 Gene Expression in Fungi IMA Fungus. Jun, 2011 | Pubmed ID: 22679585 Sex-based Differences in Susceptibility to Respiratory and Systemic Pneumococcal Disease in Mice The Journal of Infectious Diseases. Dec, 2011 | Pubmed ID: 22021621 Streptococcus Pyogenes Antigen I/II-family Polypeptide AspA Shows Differential Ligand-binding Properties and Mediates Biofilm Formation Molecular Microbiology. Aug, 2011 | Pubmed ID: 21736640 The Integrins Mac-1 and Alpha4beta1 Perform Crucial Roles in Neutrophil and T Cell Recruitment to Lungs During Streptococcus Pneumoniae Infection Journal of Immunology (Baltimore, Md. : 1950). May, 2011 | Pubmed ID: 21460207 Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4 PLoS Pathogens. 2010 | Pubmed ID: 21085613 A Subtype of a Pseudomonas Aeruginosa Cystic Fibrosis Epidemic Strain Exhibits Enhanced Virulence in a Murine Model of Acute Respiratory Infection The Journal of Infectious Diseases. Sep, 2010 | Pubmed ID: 20704484 Human Lung Mast Cells Mediate Pneumococcal Cell Death in Response to Activation by Pneumolysin Journal of Immunology (Baltimore, Md. : 1950). Jun, 2010 | Pubmed ID: 20483738 Pathogenicity Islands PAPI-1 and PAPI-2 Contribute Individually and Synergistically to the Virulence of Pseudomonas Aeruginosa Strain PA14 Infection and Immunity. Apr, 2010 | Pubmed ID: 20123716 The Immunising Effect of Pneumococcal Nasopharyngeal Colonisation; Protection Against Future Colonisation and Fatal Invasive Disease Immunobiology. Apr, 2010 | Pubmed ID: 20071053 Macrophages from BALB/c and CBA/Ca Mice Differ in Their Cellular Responses to Streptococcus Pneumoniae Journal of Leukocyte Biology. Apr, 2010 | Pubmed ID: 20028774 Sialic Acid: a Preventable Signal for Pneumococcal Biofilm Formation, Colonization, and Invasion of the Host The Journal of Infectious Diseases. May, 2009 | Pubmed ID: 19392624 Increased TNF Expression in CD43++ Murine Blood Monocytes Immunology Letters. Jun, 2008 | Pubmed ID: 18468696 The Role of Streptococcus Pneumoniae Virulence Factors in Host Respiratory Colonization and Disease Nature Reviews. Microbiology. Apr, 2008 | Pubmed ID: 18340341 The Ability to Utilize Mucin Affects the Regulation of Virulence Gene Expression in Streptococcus Pneumoniae FEMS Microbiology Letters. Jan, 2008 | Pubmed ID: 18053067 MobilomeFINDER: Web-based Tools for in Silico and Experimental Discovery of Bacterial Genomic Islands Nucleic Acids Research. Jul, 2007 | Pubmed ID: 17537813 The Cathepsin B Inhibitor, Z-FA-FMK, Inhibits Human T Cell Proliferation in Vitro and Modulates Host Response to Pneumococcal Infection in Vivo Journal of Immunology (Baltimore, Md. : 1950). Sep, 2006 | Pubmed ID: 16951345 Switch from Planktonic to Sessile Life: a Major Event in Pneumococcal Pathogenesis Molecular Microbiology. Sep, 2006 | Pubmed ID: 16925554 Pneumococcal Neuraminidases A and B Both Have Essential Roles During Infection of the Respiratory Tract and Sepsis Infection and Immunity. Jul, 2006 | Pubmed ID: 16790774 Susceptibility and Resistance to Pneumococcal Disease in Mice Briefings in Functional Genomics & Proteomics. Nov, 2005 | Pubmed ID: 16420749 Identification of a Detrimental Role for NK Cells in Pneumococcal Pneumonia and Sepsis in Immunocompromised Hosts Microbes and Infection / Institut Pasteur. May, 2005 | Pubmed ID: 15893495 CD4-T-lymphocyte Interactions with Pneumolysin and Pneumococci Suggest a Crucial Protective Role in the Host Response to Pneumococcal Infection Infection and Immunity. May, 2004 | Pubmed ID: 15102777 Protein Serine/threonine Kinase StkP Positively Controls Virulence and Competence in Streptococcus Pneumoniae Infection and Immunity. Apr, 2004 | Pubmed ID: 15039376 The Innate Immune Response to Pneumococcal Lung Infection: the Untold Story Trends in Immunology. Mar, 2004 | Pubmed ID: 15036042 Binding and Agglutination of Streptococcus Pneumoniae by Human Surfactant Protein D (SP-D) Vary Between Strains, but SP-D Fails to Enhance Killing by Neutrophils Infection and Immunity. Feb, 2004 | Pubmed ID: 14742512 The MicAB Two-component Signaling System is Involved in Virulence of Streptococcus Pneumoniae Infection and Immunity. Nov, 2003 | Pubmed ID: 14573696 Pneumococcal Behavior and Host Responses During Bronchopneumonia Are Affected Differently by the Cytolytic and Complement-activating Activities of Pneumolysin Infection and Immunity. Apr, 2003 | Pubmed ID: 12654795 Upper and Lower Respiratory Tract Infection by Streptococcus Pneumoniae is Affected by Pneumolysin Deficiency and Differences in Capsule Type Infection and Immunity. Jun, 2002 | Pubmed ID: 12010976 Role of Inflammatory Mediators in Resistance and Susceptibility to Pneumococcal Infection Infection and Immunity. Mar, 2002 | Pubmed ID: 11854243 Experimental Human Pneumococcal Carriage Jenna F. Gritzfeld1, Angie D. Wright1,2,3, Andrea M. Collins1,2,4, Shaun H. Pennington1, Adam K.A. Wright5, Aras Kadioglu6, Daniela M. Ferreira1, Stephen B. Gordon1 1Respiratory Infection Group, Liverpool School of Tropical Medicine, 2Royal Liverpool and Broadgreen, University Hospital Trust, 3Comprehensive Local Research Network, 4NIHR Biomedical Research Centre in Microbial Diseases, Royal Liverpool and Broadgreen University Hospitals NHS Trust, 5Institute of Lung Health, Respiratory Biomedical Unit, University Hospitals of Leicester NHS Trust & University of Leicester, 6Department of Clinical Infection Microbiology & Immunology, Institute of Infection & Global Health, University of Liverpool JoVE 50115 Medicina
Experimental Human Pneumococcal Carriage Jenna F. Gritzfeld1, Angie D. Wright1,2,3, Andrea M. Collins1,2,4, Shaun H. Pennington1, Adam K.A. Wright5, Aras Kadioglu6, Daniela M. Ferreira1, Stephen B. Gordon1 1Respiratory Infection Group, Liverpool School of Tropical Medicine, 2Royal Liverpool and Broadgreen, University Hospital Trust, 3Comprehensive Local Research Network, 4NIHR Biomedical Research Centre in Microbial Diseases, Royal Liverpool and Broadgreen University Hospitals NHS Trust, 5Institute of Lung Health, Respiratory Biomedical Unit, University Hospitals of Leicester NHS Trust & University of Leicester, 6Department of Clinical Infection Microbiology & Immunology, Institute of Infection & Global Health, University of Liverpool JoVE 50115 Medicina