Boris Zhivotovsky Faculty of Medicine Lomonosov Moscow State University Biography Publications Institution JoVE Articles Boris Zhivotovsky has not added a biography. If you are Boris Zhivotovsky and would like to personalize this page please email our Author Liaison for assistance. Publications Drug Toxicity Assessment: Cell Proliferation Versus Cell Death Cell Death Discovery. Oct, 2022 | Pubmed ID: 36241623 Unveiling Caspase-2 Regulation by Non-coding RNAs Cell Death & Disease. Sep, 2022 | Pubmed ID: 36171196 Mitochondrial Sirtuin 3 and Various Cell Death Modalities Frontiers in Cell and Developmental Biology. 2022 | Pubmed ID: 35938164 Caspase-2 is a Mediator of Apoptotic Signaling in Response to Gemtuzumab Ozogamicin in Acute Myeloid Leukemia Cell Death Discovery. Jun, 2022 | Pubmed ID: 35690610 Necroptosis As a Novel Facet of Mitotic Catastrophe International Journal of Molecular Sciences. Mar, 2022 | Pubmed ID: 35409093 Induction and Detection of Mitophagy Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 34972995 A Balance Between Autophagy and Other Cell Death Modalities in Cancer Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 34972982 Nonresonant CARS Imaging of Porous and Solid Silicon Nanoparticles in Human Cells ACS Biomaterials Science & Engineering. Oct, 2022 | Pubmed ID: 34553922 Mitophagy in Carcinogenesis and Cancer Treatment Discover. Oncology. Dec, 2021 | Pubmed ID: 35201480 Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors Cancers. Dec, 2021 | Pubmed ID: 35008345 A Link Between Mitotic Defects and Mitotic Catastrophe: Detection and Cell Fate Biology Direct. 12, 2021 | Pubmed ID: 34886882 A Long Way to Go: Caspase Inhibitors in Clinical Use Cell Death & Disease. 10, 2021 | Pubmed ID: 34654807 Optical Monitoring of the Biodegradation of Porous and Solid Silicon Nanoparticles Nanomaterials (Basel, Switzerland). Aug, 2021 | Pubmed ID: 34578485 Receptor-Mediated Mitophagy Rescues Cancer Cells Under Hypoxic Conditions Cancers. Aug, 2021 | Pubmed ID: 34439183 Anastasis: Return Journey from Cell Death Cancers. Jul, 2021 | Pubmed ID: 34359573 Platinum Drugs and Taxanes: Can We Overcome Resistance? Cell Death Discovery. Jun, 2021 | Pubmed ID: 34226520 Long Non-coding RNAs: A View to Kill Ovarian Cancer Biochimica Et Biophysica Acta. Reviews on Cancer. 08, 2021 | Pubmed ID: 34157315 Modeling Hypoxia Facilitates Cancer Cell Survival Through Downregulation of P53 Expression Chemico-biological Interactions. Aug, 2021 | Pubmed ID: 34126102 Analysis of Mitochondrial Dysfunction During Cell Death Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34060044 Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells Cells. 04, 2021 | Pubmed ID: 33918601 Caspase-2 As a Master Regulator of Genomic Stability Trends in Cell Biology. 09, 2021 | Pubmed ID: 33752921 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition) Autophagy. Feb, 2021 | Pubmed ID: 33634751 BNIP3 in Lung Cancer: To Kill or Rescue? Cancers. Nov, 2020 | Pubmed ID: 33207677 BNIP3 As a Regulator of Cisplatin-Induced Apoptosis Biochemistry. Biokhimiia. Oct, 2020 | Pubmed ID: 33202209 Programmed Cell Death: Historical Notes from Russia Biochemistry. Biokhimiia. Oct, 2020 | Pubmed ID: 33202198 Upregulation of Mcl-1S Causes Cell-Cycle Perturbations and DNA Damage Accumulation Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33072738 Requirement for Serine-384 in Caspase-2 Processing and Activity Cell Death & Disease. 10, 2020 | Pubmed ID: 33011746 In Memoriam: Sten Orrenius (1937-2020) Biochemical and Biophysical Research Communications. 09, 2020 | Pubmed ID: 32819593 On Sten Orrenius (1937-2020) Cell Death and Differentiation. 09, 2020 | Pubmed ID: 32694651 Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases Cancers. Apr, 2020 | Pubmed ID: 32316560 Mcl-1 As a "barrier" in Cancer Treatment: Can We Target It Now? International Review of Cell and Molecular Biology. 2020 | Pubmed ID: 32247581 Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases Molecular Cell. 03, 2020 | Pubmed ID: 32142688 Desmin Mutations Result in Mitochondrial Dysfunction Regardless of Their Aggregation Properties Biochimica Et Biophysica Acta. Molecular Basis of Disease. 06, 2020 | Pubmed ID: 32105824 To Eat or to Die: Deciphering Selective Forms of Autophagy Trends in Biochemical Sciences. 04, 2020 | Pubmed ID: 32044127 Saga of Mcl-1: Regulation from Transcription to Degradation Cell Death and Differentiation. 02, 2020 | Pubmed ID: 31907390 The DNA-damage Response and Nuclear Events As Regulators of Nonapoptotic Forms of Cell Death Oncogene. 01, 2020 | Pubmed ID: 31462710 Distinct Effects of Etoposide on Glutamine-addicted Neuroblastoma Cellular and Molecular Life Sciences : CMLS. Mar, 2020 | Pubmed ID: 31392350 Biodegradable Porous Silicon Nanocontainers As an Effective Drug Carrier for Regulation of the Tumor Cell Death Pathways ACS Biomaterials Science & Engineering. Nov, 2019 | Pubmed ID: 33405660 Mitochondrial Involvement in Migration, Invasion and Metastasis Frontiers in Cell and Developmental Biology. 2019 | Pubmed ID: 31921862 Isolation of High-Molecular-Weight Activation Complexes of Initiator Caspases in DNA Damage Bulletin of Experimental Biology and Medicine. Nov, 2019 | Pubmed ID: 31758380 Molecular Comprehension of Mcl-1: From Gene Structure to Cancer Therapy Trends in Cell Biology. 07, 2019 | Pubmed ID: 31030977 Involvement of Mitophagy in Cisplatin-induced Cell Death Regulation Biological Chemistry. 01, 2019 | Pubmed ID: 29924729 2-Deoxy-D-glucose Has Distinct and Cell Line-specific Effects on the Survival of Different Cancer Cells Upon Antitumor Drug Treatment The FEBS Journal. 12, 2018 | Pubmed ID: 30375744 [Caspase-2 As an Oncosupressor and Metabolism Regulator: What Life Will Bring over the Long Run?] Molekuliarnaia Biologiia. Sep-Oct, 2018 | Pubmed ID: 30363050 Apoptosis Regulation by Subcellular Relocation of Caspases Scientific Reports. 08, 2018 | Pubmed ID: 30111833 Caspase-2 is a Negative Regulator of Necroptosis The International Journal of Biochemistry & Cell Biology. 09, 2018 | Pubmed ID: 30025878 Alterations in the Nucleocytoplasmic Transport in Apoptosis: Caspases Lead the Way Cell Proliferation. Oct, 2018 | Pubmed ID: 29947118 P53-Autophagy-Metastasis Link Cancers. May, 2018 | Pubmed ID: 29783720 Caspase-2 Associates with FAN Through Direct Interaction and Overlapping Functionality Biochemical and Biophysical Research Communications. 05, 2018 | Pubmed ID: 29621545 Cell Death-based Treatment of Various Diseases: a Fifty-year Journey Cell Death & Disease. 01, 2018 | Pubmed ID: 29371674 Cell Death-based Treatment of Lung Adenocarcinoma Cell Death & Disease. 01, 2018 | Pubmed ID: 29371589 Cell Death-based Treatment of Neuroblastoma Cell Death & Disease. 01, 2018 | Pubmed ID: 29371588 Molecular Mechanisms of Cell Death: Recommendations of the Nomenclature Committee on Cell Death 2018 Cell Death and Differentiation. Mar, 2018 | Pubmed ID: 29362479 A Caspase-2-RFXANK Interaction and Its Implication for MHC Class II Expression Cell Death & Disease. 01, 2018 | Pubmed ID: 29362422 Modulation of Mcl-1 Transcription by Serum Deprivation Sensitizes Cancer Cells to Cisplatin Biochimica Et Biophysica Acta. General Subjects. Mar, 2018 | Pubmed ID: 29203282 Suppressed Translation As a Mechanism of Initiation of CASP8 (caspase 8)-dependent Apoptosis in Autophagy-deficient NSCLC Cells Under Nutrient Limitation Autophagy. 2018 | Pubmed ID: 29165042 Mitochondria-targeted Betulinic and Ursolic Acid Derivatives: Synthesis and Anticancer Activity MedChemComm. Oct, 2017 | Pubmed ID: 30108714 Involvement of Autophagy in the Outcome of Mitotic Catastrophe Scientific Reports. 11, 2017 | Pubmed ID: 29109414 Mitophagy: Link to Cancer Development and Therapy Biochemical and Biophysical Research Communications. 01, 2017 | Pubmed ID: 28212727 Post-translational Modification of Caspases: The Other Side of Apoptosis Regulation Trends in Cell Biology. 05, 2017 | Pubmed ID: 28188028 Contrasting Effects of Glutamine Deprivation on Apoptosis Induced by Conventionally Used Anticancer Drugs Biochimica Et Biophysica Acta. Molecular Cell Research. Mar, 2017 | Pubmed ID: 27993669 Caloric Restriction - A Promising Anti-cancer Approach: From Molecular Mechanisms to Clinical Trials Biochimica Et Biophysica Acta. Reviews on Cancer. Jan, 2017 | Pubmed ID: 27871964 Reactive Oxygen Species Regulate a Balance Between Mitotic Catastrophe and Apoptosis The International Journal of Biochemistry & Cell Biology. 12, 2016 | Pubmed ID: 27840153 Suppressed Translation and ULK1 Degradation As Potential Mechanisms of Autophagy Limitation Under Prolonged Starvation Autophagy. 11, 2016 | Pubmed ID: 27629431 Tudor Staphylococcal Nuclease: Biochemistry and Functions Cell Death and Differentiation. 11, 2016 | Pubmed ID: 27612014 Targeting Succinate:ubiquinone Reductase Potentiates the Efficacy of Anticancer Therapy Biochimica Et Biophysica Acta. 08, 2016 | Pubmed ID: 27140478 Mitotic Catastrophe and Cancer Drug Resistance: A Link That Must to Be Broken Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Jan, 2016 | Pubmed ID: 26830311 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Role of the Nucleus in Apoptosis: Signaling and Execution Cellular and Molecular Life Sciences : CMLS. Dec, 2015 | Pubmed ID: 26346492 Calcium and Mitochondria in the Regulation of Cell Death Biochemical and Biophysical Research Communications. Apr, 2015 | Pubmed ID: 25998735 Cell Death Controlling Complexes and Their Potential Therapeutic Role Cellular and Molecular Life Sciences : CMLS. Feb, 2015 | Pubmed ID: 25323133 Mitochondria--a Bullseye in Cancer Therapy Mitochondrion. Nov, 2014 | Pubmed ID: 25315654 Mitochondrial Substrates in Cancer: Drivers or Passengers? Mitochondrion. Nov, 2014 | Pubmed ID: 25179741 MiRNAs in Lung Cancer: a Link to Aging Ageing Research Reviews. Sep, 2014 | Pubmed ID: 24631464 Targeting Mitochondria by α-tocopheryl Succinate Overcomes Hypoxia-mediated Tumor Cell Resistance to Treatment Cellular and Molecular Life Sciences : CMLS. Jun, 2014 | Pubmed ID: 24142346 Suppression of Basal Autophagy Reduces Lung Cancer Cell Proliferation and Enhances Caspase-dependent and -independent Apoptosis by Stimulating ROS Formation Autophagy. Jul, 2012 | Pubmed ID: 22562073 Knock-down of Core Proteins Regulating MicroRNA Biogenesis Has No Effect on Sensitivity of Lung Cancer Cells to Ionizing Radiation PloS One. 2012 | Pubmed ID: 22479364 Exploring Caspase Mutations and Post-Translational Modification by Molecular Modeling Approaches Dmitry K. Nilov1, Alexey V. Zamaraev2, Boris Zhivotovsky2,3, Gelina S. Kopeina2 1Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 2Faculty of Medicine, Lomonosov Moscow State University, 3Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute JoVE 64206 Biologia
Exploring Caspase Mutations and Post-Translational Modification by Molecular Modeling Approaches Dmitry K. Nilov1, Alexey V. Zamaraev2, Boris Zhivotovsky2,3, Gelina S. Kopeina2 1Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 2Faculty of Medicine, Lomonosov Moscow State University, 3Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute JoVE 64206 Biologia