C. Dirk Keene Department of Pathology University of Washington Biography Publications Institution JoVE Articles C. Dirk Keene has not added a biography. If you are C. Dirk Keene and would like to personalize this page please email our Author Liaison for assistance. Publications Brain-specific Repression of AMPKα1 Alleviates Pathophysiology in Alzheimer's Model Mice The Journal of Clinical Investigation. Mar, 2020 | Pubmed ID: 32213711 Heterozygous Missense Variants Cause Ataxia, Cognitive Decline, and STUB1 Mislocalization Neurology. Genetics. Apr, 2020 | Pubmed ID: 32211513 Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy Journal of Neuropathology and Experimental Neurology. Mar, 2020 | Pubmed ID: 32186726 Nasolacrimal Lymphangioma Presenting With Hemolacria Ophthalmic Plastic and Reconstructive Surgery. Feb, 2020 | Pubmed ID: 32118845 Exceptionally Low Likelihood of Alzheimer's Dementia in APOE2 Homozygotes from a 5,000-person Neuropathological Study Nature Communications. Feb, 2020 | Pubmed ID: 32015339 Redefining Transcriptional Regulation of the APOE Gene and Its Association with Alzheimer's Disease PloS One. 2020 | Pubmed ID: 31978088 Hyperphosphorylated Tau, Increased Adenylate Cyclase 5 (ADCY5) Immunoreactivity, but No Neuronal Loss in ADCY5-Dyskinesia Movement Disorders Clinical Practice. Jan, 2020 | Pubmed ID: 31970214 β-amyloid Redirects Norepinephrine Signaling to Activate the Pathogenic GSK3β/tau Cascade Science Translational Medicine. Jan, 2020 | Pubmed ID: 31941827 Transcriptomic Profiles of Sepsis in the Human Brain American Journal of Respiratory and Critical Care Medicine. Jan, 2020 | Pubmed ID: 31940219 Traumatic Brain Injury Triggers APP and Tau Cleavage by Delta-secretase, Mediating Alzheimer's Disease Pathology Progress in Neurobiology. Feb, 2020 | Pubmed ID: 31778772 Activity of the Poly(A) Binding Protein MSUT2 Determines Susceptibility to Pathological Tau in the Mammalian Brain Science Translational Medicine. Dec, 2019 | Pubmed ID: 31852801 Genome Wide Analysis Reveals Heparan Sulfate Epimerase Modulates TDP-43 Proteinopathy PLoS Genetics. 12, 2019 | Pubmed ID: 31834878 Chronic Traumatic Encephalopathy Neuropathology Might Not Be Inexorably Progressive or Unique to Repetitive Neurotrauma Brain : a Journal of Neurology. Dec, 2019 | Pubmed ID: 31670780 Mitotic Index Thresholds Do Not Predict Clinical Outcome for IDH-Mutant Astrocytoma Journal of Neuropathology and Experimental Neurology. Nov, 2019 | Pubmed ID: 31529048 Cross Species Application of Quantitative Neuropathology Assays Developed for Clinical Alzheimer's Disease Samples Pathobiology of Aging & Age Related Diseases. 2019 | Pubmed ID: 31528297 Sex Differences in the Genetic Predictors of Alzheimer's Pathology Brain : a Journal of Neurology. Sep, 2019 | Pubmed ID: 31497858 Targeted Quantitative Proteomic Approach for High-Throughput Quantitative Profiling of Small GTPases in Brain Tissues of Alzheimer's Disease Patients Analytical Chemistry. Oct, 2019 | Pubmed ID: 31460748 Conserved Cell Types with Divergent Features in Human Versus Mouse Cortex Nature. 09, 2019 | Pubmed ID: 31435019 Author Correction: Genetic Meta-analysis of Diagnosed Alzheimer's Disease Identifies New Risk Loci and Implicates Aβ, Tau, Immunity and Lipid Processing Nature Genetics. Sep, 2019 | Pubmed ID: 31417202 A Soluble Tau Fragment Generated by Caspase-2 is Associated with Dementia in Lewy Body Disease Acta Neuropathologica Communications. 07, 2019 | Pubmed ID: 31362787 Quantitative Analysis of Chondroitin Sulfate Disaccharides from Human and Rodent Fixed Brain Tissue by Electrospray Ionization-tandem Mass Spectrometry Glycobiology. 11, 2019 | Pubmed ID: 31361007 Reply: LATE to the PART-y Brain : a Journal of Neurology. Sep, 2019 | Pubmed ID: 31359039 Resistance and Resilience to Alzheimer's Disease Pathology Are Associated with Reduced Cortical PTau and Absence of Limbic-predominant Age-related TDP-43 Encephalopathy in a Community-based Cohort Acta Neuropathologica Communications. 06, 2019 | Pubmed ID: 31174609 Aβ and Tau Prion-like Activities Decline with Longevity in the Alzheimer's Disease Human Brain Science Translational Medicine. 05, 2019 | Pubmed ID: 31043574 Limbic-predominant Age-related TDP-43 Encephalopathy (LATE): Consensus Working Group Report Brain : a Journal of Neurology. 06, 2019 | Pubmed ID: 31039256 Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia American Journal of Human Genetics. 05, 2019 | Pubmed ID: 30982608 Cognitive Resilience to Alzheimer's Disease Pathology in the Human Brain Journal of Alzheimer's Disease : JAD. 2019 | Pubmed ID: 30909217 Ophthalmology-Based Neuropathology Risk Factors: Diabetic Retinopathy is Associated with Deep Microinfarcts in a Community-Based Autopsy Study Journal of Alzheimer's Disease : JAD. 2019 | Pubmed ID: 30883356 Genetic Meta-analysis of Diagnosed Alzheimer's Disease Identifies New Risk Loci and Implicates Aβ, Tau, Immunity and Lipid Processing Nature Genetics. 03, 2019 | Pubmed ID: 30820047 Primum Non Nocere: a Call for Balance when Reporting on CTE The Lancet. Neurology. Mar, 2019 | Pubmed ID: 30784550 Genetic Reduction of EEF2 Kinase Alleviates Pathophysiology in Alzheimer's Disease Model Mice The Journal of Clinical Investigation. 02, 2019 | Pubmed ID: 30667373 Preventive Action of Benztropine on Platinum-induced Peripheral Neuropathies and Tumor Growth Acta Neuropathologica Communications. 01, 2019 | Pubmed ID: 30657060 Correction: Genetic Data and Cognitively Defined Late-onset Alzheimer's Disease Subgroups Molecular Psychiatry. Jan, 2019 | Pubmed ID: 30647434 Luminex-based Quantification of Alzheimer's Disease Neuropathologic Change in Formalin-fixed Post-mortem Human Brain Tissue Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2019 | Pubmed ID: 30573871 Increased Hyaluronan and TSG-6 in Association with Neuropathologic Changes of Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2019 | Pubmed ID: 30507579 A Nonhuman Primate Model of Early Alzheimer's Disease Pathologic Change: Implications for Disease Pathogenesis Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 01, 2019 | Pubmed ID: 30467082 Mass Synaptometry: High-dimensional Multi Parametric Assay for Single Synapses Journal of Neuroscience Methods. 01, 2019 | Pubmed ID: 30465796 Neuronal Susceptibility to Beta-amyloid Toxicity and Ischemic Injury Involves Histone Deacetylase-2 Regulation of Endophilin-B1 Brain Pathology (Zurich, Switzerland). 03, 2019 | Pubmed ID: 30028551 Flow Cytometric Evaluation of Crude Synaptosome Preparation As a Way to Study Synaptic Alteration in Neurodegenerative Diseases Neuromethods. 2018 | Pubmed ID: 32139977 Genetic Data and Cognitively Defined Late-onset Alzheimer's Disease Subgroups Molecular Psychiatry. Dec, 2018 | Pubmed ID: 30514930 H-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human Versus Mouse Cerebral Cortex Neuron. Dec, 2018 | Pubmed ID: 30392798 Modeling Alzheimer's Disease in Progeria Mice. An Age-related Concept Pathobiology of Aging & Age Related Diseases. 2018 | Pubmed ID: 30319737 Glia-specific APOE Epigenetic Changes in the Alzheimer's Disease Brain Brain Research. 11, 2018 | Pubmed ID: 30081037 Localized Crystal-storing Histiocytosis of the Posterior Fossa Neuropathology : Official Journal of the Japanese Society of Neuropathology. Oct, 2018 | Pubmed ID: 30066398 Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 30056417 Sex-specific Genetic Predictors of Alzheimer's Disease Biomarkers Acta Neuropathologica. 12, 2018 | Pubmed ID: 29967939 A Robust Ex Vivo Experimental Platform for Molecular-genetic Dissection of Adult Human Neocortical Cell Types and Circuits Scientific Reports. 05, 2018 | Pubmed ID: 29849137 Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau JAMA Neurology. 08, 2018 | Pubmed ID: 29801024 An Anatomic Transcriptional Atlas of Human Glioblastoma Science (New York, N.Y.). 05, 2018 | Pubmed ID: 29748285 APOE DNA Methylation is Altered in Lewy Body Dementia Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Jul, 2018 | Pubmed ID: 29544979 Dopamine D Receptor-Positive Neurons in the Lateral Nucleus of the Cerebellum Contribute to Cognitive Behavior Biological Psychiatry. 09, 2018 | Pubmed ID: 29478701 Leptomeninges-Derived Induced Pluripotent Stem Cells and Directly Converted Neurons From Autopsy Cases With Varying Neuropathologic Backgrounds Journal of Neuropathology and Experimental Neurology. 05, 2018 | Pubmed ID: 29474672 Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project Journal of Neurotrauma. 07, 2018 | Pubmed ID: 29421973 Pathological Phosphorylation of Tau and TDP-43 by TTBK1 and TTBK2 Drives Neurodegeneration Molecular Neurodegeneration. 02, 2018 | Pubmed ID: 29409526 DNA Methylation of TOMM40-APOE-APOC2 in Alzheimer's Disease Journal of Human Genetics. Apr, 2018 | Pubmed ID: 29371683 Structural Heterogeneity and Intersubject Variability of Aβ in Familial and Sporadic Alzheimer's Disease Proceedings of the National Academy of Sciences of the United States of America. 01, 2018 | Pubmed ID: 29311311 First Confirmed Case of Chronic Traumatic Encephalopathy in a Professional Bull Rider Acta Neuropathologica. 02, 2018 | Pubmed ID: 29285625 Vasodilator Dysfunction and Oligodendrocyte Dysmaturation in Aging White Matter Annals of Neurology. 01, 2018 | Pubmed ID: 29283444 Associations Between Use of Specific Analgesics and Concentrations of Amyloid-β 42 or Phospho-Tau in Regions of Human Cerebral Cortex Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29226863 The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29103039 Psychosis in Spinocerebellar Ataxias: a Case Series and Study of Tyrosine Hydroxylase in Substantia Nigra Cerebellum (London, England). 04, 2018 | Pubmed ID: 28887803 Application of the Condensed Protocol for the NIA-AA Guidelines for the Neuropathological Assessment of Alzheimer's Disease in an Academic Clinical Practice Histopathology. Feb, 2018 | Pubmed ID: 28815699 Susceptibility to Neurofibrillary Tangles: Role of the PTPRD Locus and Limited Pleiotropy with Other Neuropathologies Molecular Psychiatry. 06, 2018 | Pubmed ID: 28322283 Neuropathological and Transcriptomic Characteristics of the Aged Brain ELife. Nov, 2017 | Pubmed ID: 29120328 Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism Oxidative Medicine and Cellular Longevity. 2017 | Pubmed ID: 29098063 Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son Journal of Huntington's Disease. 2017 | Pubmed ID: 29036832 Mixed Neuropathologies and Associations with Domain-specific Cognitive Decline Neurology. Oct, 2017 | Pubmed ID: 28939667 Association Between Cholesterol Exposure and Neuropathological Findings: The ACT Study Journal of Alzheimer's Disease : JAD. 2017 | Pubmed ID: 28731431 Rare Coding Variants in PLCG2, ABI3, and TREM2 Implicate Microglial-mediated Innate Immunity in Alzheimer's Disease Nature Genetics. 09, 2017 | Pubmed ID: 28714976 Incidence of Cognitively Defined Late-onset Alzheimer's Dementia Subgroups from a Prospective Cohort Study Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Dec, 2017 | Pubmed ID: 28623677 Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies Journal of Neuropathology and Experimental Neurology. Jun, 2017 | Pubmed ID: 28499012 Alzheimer's Disease Neuropathologic Change, Lewy Body Disease, and Vascular Brain Injury in Clinic- and Community-based Samples Neurobiology of Aging. May, 2017 | Pubmed ID: 28236716 Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE ε4 The American Journal of Pathology. Apr, 2017 | Pubmed ID: 28212814 Immunohistochemical Profiling Including Beta-catenin in Conjunctival Melanocytic Lesions Experimental and Molecular Pathology. 04, 2017 | Pubmed ID: 28161440 Performance of a Condensed Protocol That Reduces Effort and Cost of NIA-AA Guidelines for Neuropathologic Assessment of Alzheimer Disease Journal of Neuropathology and Experimental Neurology. 01, 2017 | Pubmed ID: 28062571 Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: a Retrospective Analysis The Lancet. Neurology. Jan, 2017 | Pubmed ID: 27979356 Mixed Neuropathologies and Estimated Rates of Clinical Progression in a Large Autopsy Sample Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Jun, 2017 | Pubmed ID: 27870939 Primary Gliosarcoma of the Optic Nerve: A Unique Adult Optic Pathway Glioma Ophthalmic Plastic and Reconstructive Surgery. Jul/Aug, 2017 | Pubmed ID: 27792048 Orbital Peripheral Nerve Sheath Tumors Survey of Ophthalmology. Jan - Feb, 2017 | Pubmed ID: 27570221 Unusually Long Duration and Delayed Penetrance in a Family with FTD and Mutation in MAPT (V337M) American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 01, 2017 | Pubmed ID: 26990251 Genome Sequencing in a Case of Niemann-Pick Type C Cold Spring Harbor Molecular Case Studies. 11, 2016 | Pubmed ID: 27900365 Glucose Levels During Life and Neuropathologic Findings at Autopsy Among People Never Treated for Diabetes Neurobiology of Aging. 12, 2016 | Pubmed ID: 27644076 Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 09, 2016 | Pubmed ID: 27567813 The Phosphatase Calcineurin Regulates Pathological TDP-43 Phosphorylation Acta Neuropathologica. 10, 2016 | Pubmed ID: 27473149 Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings JAMA Neurology. 09, 2016 | Pubmed ID: 27400367 Neuropathological Assessment and Validation of Mouse Models for Alzheimer's Disease: Applying NIA-AA Guidelines Pathobiology of Aging & Age Related Diseases. 2016 | Pubmed ID: 27317189 TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy Neuron. 05, 2016 | Pubmed ID: 27196974 Mutational Status of IDH1 in Uveal Melanoma Experimental and Molecular Pathology. 06, 2016 | Pubmed ID: 27155448 Unbiased Stereological Analysis of Reactive Astrogliosis to Estimate Age-Associated Cerebral White Matter Injury Journal of Neuropathology and Experimental Neurology. 06, 2016 | Pubmed ID: 27142644 Characterization of Cognitive Impairments and Neurotransmitter Changes in a Novel Transgenic Mouse Lacking Slc10a4 Neuroscience. Jun, 2016 | Pubmed ID: 27001174 Precision Medicine: Clarity for the Complexity of Dementia The American Journal of Pathology. Mar, 2016 | Pubmed ID: 26724389 The First NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy Acta Neuropathologica. Jan, 2016 | Pubmed ID: 26667418 Importance of Home Study Visit Capacity in Dementia Studies Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Apr, 2016 | Pubmed ID: 26602628 Impaired Eukaryotic Elongation Factor 1A Expression in Alzheimer's Disease Neuro-degenerative Diseases. 2016 | Pubmed ID: 26551858 Clinical-pathologic Correlations in Vascular Cognitive Impairment and Dementia Biochimica Et Biophysica Acta. 05, 2016 | Pubmed ID: 26319420 The APOE Gene is Differentially Methylated in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2015 | Pubmed ID: 26402071 Multiplexed In-cell Immunoassay for Same-sample Protein Expression Profiling Scientific Reports. Sep, 2015 | Pubmed ID: 26328896 Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease Journal of Neuropathology and Experimental Neurology. Jul, 2015 | Pubmed ID: 26083568 Relative Contributions of Severe Dopaminergic Neuron Ablation and Dopamine Depletion to Cognitive Impairment Experimental Neurology. Sep, 2015 | Pubmed ID: 26079646 Wild-type Microglia Do Not Reverse Pathology in Mouse Models of Rett Syndrome Nature. May, 2015 | Pubmed ID: 25993969 Loss of Endophilin-B1 Exacerbates Alzheimer's Disease Pathology Brain : a Journal of Neurology. Jul, 2015 | Pubmed ID: 25981964 Partial Depletion of Striatal Dopamine Enhances Penetrance of Cognitive Deficits in a Transgenic Mouse Model of Alzheimer's Disease Journal of Neuroscience Research. Sep, 2015 | Pubmed ID: 25824456 Orbital Metastasis of Undifferentiated/Anaplastic Thyroid Carcinoma Ophthalmic Plastic and Reconstructive Surgery. Sep-Oct, 2015 | Pubmed ID: 25679298 Different Mechanisms of Apolipoprotein E Isoform-dependent Modulation of Prostaglandin E2 Production and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Expression After Innate Immune Activation of Microglia FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2015 | Pubmed ID: 25593125 Cerebral Cortical Aβ42 and PHF-τ in 325 Consecutive Brain Autopsies Stratified by Diagnosis, Location, and APOE Journal of Neuropathology and Experimental Neurology. Feb, 2015 | Pubmed ID: 25575135 Prostaglandin E2 Receptor Subtype 2 Regulation of Scavenger Receptor CD36 Modulates Microglial Aβ42 Phagocytosis The American Journal of Pathology. Jan, 2015 | Pubmed ID: 25452117 Hemorrhagic Collision Metastasis in a Cerebral Arteriovenous Malformation Journal of Neurointerventional Surgery. Oct, 2015 | Pubmed ID: 25261441 APOE Genotype-dependent Modulation of Astrocyte Chemokine CCL3 Production Glia. Jan, 2015 | Pubmed ID: 25092803 Orbital Extension of Anterior Uveal Melanoma After Baerveldt Tube Shunt Implantation Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. Dec, 2014 | Pubmed ID: 25433745 Hemorrhagic Collision Metastasis in a Cerebral Arteriovenous Malformation BMJ Case Reports. Sep, 2014 | Pubmed ID: 25239982 Wild-type Bone Marrow Transplant Partially Reverses Neuroinflammation in Progranulin-deficient Mice Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2014 | Pubmed ID: 25199051 Flow Cytometry Analysis of Synaptosomes from Post-mortem Human Brain Reveals Changes Specific to Lewy Body and Alzheimer's Disease Laboratory Investigation; a Journal of Technical Methods and Pathology. Oct, 2014 | Pubmed ID: 25068655 The Co-occurrence of Alzheimer's Disease and Huntington's Disease: a Neuropathological Study of 15 Elderly Huntington's Disease Subjects Journal of Huntington's Disease. 2014 | Pubmed ID: 25062863 Retinal Neovascularization and Endogenous Fungal Endophthalmitis in Intravenous Drug Users Ophthalmology. Sep, 2014 | Pubmed ID: 24863463 Therapeutic Implications of the Prostaglandin Pathway in Alzheimer's Disease Biochemical Pharmacology. Apr, 2014 | Pubmed ID: 24434190 A Case of Nodular Fasciitis Causing Compressive Optic Neuropathy Ophthalmic Plastic and Reconstructive Surgery. Mar-Apr, 2014 | Pubmed ID: 23924989 Orbital Neoplasms in Adults: Clinical, Radiologic, and Pathologic Review Radiographics : a Review Publication of the Radiological Society of North America, Inc. Oct, 2013 | Pubmed ID: 24108560 Novel Mutations in Ataxia Telangiectasia and AOA2 Associated with Prolonged Survival Journal of the Neurological Sciences. Dec, 2013 | Pubmed ID: 24090759 Epigenetic Signature and Enhancer Activity of the Human APOE Gene Human Molecular Genetics. Dec, 2013 | Pubmed ID: 23892237 APOE3, but Not APOE4, Bone Marrow Transplantation Mitigates Behavioral and Pathological Changes in a Mouse Model of Alzheimer Disease The American Journal of Pathology. Sep, 2013 | Pubmed ID: 23831297 Suppressed Retinal Degeneration in Aged Wild Type and APPswe/PS1ΔE9 Mice by Bone Marrow Transplantation PloS One. 2013 | Pubmed ID: 23750207 Perivascular, but Not Parenchymal, Cerebral Engraftment of Donor Cells After Non-myeloablative Bone Marrow Transplantation Experimental and Molecular Pathology. Aug, 2013 | Pubmed ID: 23567123 A Diagnostic Dilemma: Infectious Versus Noninfectious Multifocal Choroiditis with Panuveitis Journal of Ophthalmic Inflammation and Infection. Jan, 2013 | Pubmed ID: 23514267 Ablation of the Microglial Protein DOCK2 Reduces Amyloid Burden in a Mouse Model of Alzheimer's Disease Experimental and Molecular Pathology. Apr, 2013 | Pubmed ID: 23318649 Downregulation of Cannabinoid Receptor 1 from Neuropeptide Y Interneurons in the Basal Ganglia of Patients with Huntington's Disease and Mouse Models The European Journal of Neuroscience. Feb, 2013 | Pubmed ID: 23167744 Massive Intractable Hemoptysis Due to Idiopathic Granulomatous Pulmonary Veno-occlusive Disease Respiratory Care. May, 2013 | Pubmed ID: 23050515 Antagonism of Neuronal Prostaglandin E(2) Receptor Subtype 1 Mitigates Amyloid β Neurotoxicity in Vitro Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Mar, 2013 | Pubmed ID: 22718277 Gravin is a Transitory Effector of Polo-like Kinase 1 During Cell Division Molecular Cell. Nov, 2012 | Pubmed ID: 23063527 Eicosanoid Receptor Subtype-mediated Opposing Regulation of TLR-stimulated Expression of Astrocyte Glial-derived Neurotrophic Factor FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2012 | Pubmed ID: 22499581 Novel Antibody Capture Assay for Paraffin-embedded Tissue Detects Wide-ranging Amyloid Beta and Paired Helical Filament-tau Accumulation in Cognitively Normal Older Adults Brain Pathology (Zurich, Switzerland). Jul, 2012 | Pubmed ID: 21999410 Severely Impaired Learning and Altered Neuronal Morphology in Mice Lacking NMDA Receptors in Medium Spiny Neurons PloS One. 2011 | Pubmed ID: 22132236 Apolipoprotein E Isoforms and Regulation of the Innate Immune Response in Brain of Patients with Alzheimer's Disease Current Opinion in Neurobiology. Dec, 2011 | Pubmed ID: 21907569 Role of Cerebrospinal Fluid and Plasma Biomarkers in the Diagnosis of Neurodegenerative Disorders and Mild Cognitive Impairment Current Neurology and Neuroscience Reports. Oct, 2011 | Pubmed ID: 21725901 Apolipoprotein E Isoform-dependent Microglia Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2011 | Pubmed ID: 21385991 Suppressed Microglial E Prostanoid Receptor 1 Signaling Selectively Reduces Tumor Necrosis Factor Alpha and Interleukin 6 Secretion from Toll-like Receptor 3 Activation Glia. Apr, 2011 | Pubmed ID: 21319223 Comparison of Analytical Mathematical Approaches for Identifying Key Nuclear Magnetic Resonance Spectroscopy Biomarkers in the Diagnosis and Assessment of Clinical Change of Diseases The Journal of Comparative Neurology. Oct, 2010 | Pubmed ID: 20878778 Suppressed Accumulation of Cerebral Amyloid {beta} Peptides in Aged Transgenic Alzheimer's Disease Mice by Transplantation with Wild-type or Prostaglandin E2 Receptor Subtype 2-null Bone Marrow The American Journal of Pathology. Jul, 2010 | Pubmed ID: 20522650 Parahippocampal Corpora Amylacea: Case Report Neurosurgery. Jun, 2010 | Pubmed ID: 20495392 Protection of Hippocampal Neurogenesis from Toll-like Receptor 4-dependent Innate Immune Activation by Ablation of Prostaglandin E2 Receptor Subtype EP1 or EP2 The American Journal of Pathology. Jun, 2009 | Pubmed ID: 19389932 A Patient with Huntington's Disease and Long-surviving Fetal Neural Transplants That Developed Mass Lesions Acta Neuropathologica. Mar, 2009 | Pubmed ID: 19057918 Proteomics of Human Neurodegenerative Diseases Journal of Neuropathology and Experimental Neurology. Oct, 2008 | Pubmed ID: 18800015 Therapeutic Targets in Prostaglandin E2 Signaling for Neurologic Disease Current Medicinal Chemistry. 2008 | Pubmed ID: 18691044 Biomarkers for Alzheimer's Disease Expert Review of Neurotherapeutics. Aug, 2007 | Pubmed ID: 17678497 Arınma ve Caenorhabditis elegans Ekstrasellüler Veziküllerin Analizi Joshua C. Russell1, Nadia Postupna1, Alexandra Golubeva1, C. Dirk Keene1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 60596 Biologia
Arınma ve Caenorhabditis elegans Ekstrasellüler Veziküllerin Analizi Joshua C. Russell1, Nadia Postupna1, Alexandra Golubeva1, C. Dirk Keene1, Matt Kaeberlein1 1Department of Pathology, University of Washington JoVE 60596 Biologia