Cassian Sitaru Department of Dermatology University of Freiburg Biography Publications Institution JoVE Articles Cassian Sitaru has not added a biography. If you are Cassian Sitaru and would like to personalize this page please email our Author Liaison for assistance. Publications Two Japanese Cases of Dermatitis Herpetiformis Associated Each with Lung Cancer and Autoimmune Pancreatitis but Showing No Intestinal Symptom or Circulating Immunoglobulin A Antibodies to Any Known Antigens The Journal of Dermatology. Sep, 2012 | Pubmed ID: 22963165 Blocking Fcα Receptor I on Granulocytes Prevents Tissue Damage Induced by IgA Autoantibodies Journal of Immunology (Baltimore, Md. : 1950). Aug, 2012 | Pubmed ID: 22802416 Prevalence of Collagen VII-specific Autoantibodies in Patients with Autoimmune and Inflammatory Diseases BMC Immunology. 2012 | Pubmed ID: 22471736 The Flavonoid Luteolin Inhibits Fcγ-dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice PloS One. 2012 | Pubmed ID: 22328927 Why Human Pemphigoid Autoantibodies Do Not Trigger Disease by the Passive Transfer into Mice? Immunology Letters. Mar, 2012 | Pubmed ID: 22305931 Development of an ELISA for Sensitive and Specific Detection of IgA Autoantibodies Against BP180 in Pemphigoid Diseases Orphanet Journal of Rare Diseases. 2011 | Pubmed ID: 21619684 PI3Kβ Plays a Critical Role in Neutrophil Activation by Immune Complexes Science Signaling. 2011 | Pubmed ID: 21487106 Ectodomain Shedding Generates Neoepitopes on Collagen XVII, the Major Autoantigen for Bullous Pemphigoid Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010 | Pubmed ID: 20861347 Pemphigus Vulgaris is the Most Common Autoimmune Bullous Disease in Northwestern Romania International Journal of Dermatology. Jul, 2010 | Pubmed ID: 20618495 Metal Sensitization Precipitates Skin Blistering in Epidermolysis Bullosa Acquisita The Journal of Dermatology. Mar, 2010 | Pubmed ID: 20507396 The Neonatal Fc Receptor As Therapeutic Target in IgG-mediated Autoimmune Diseases Cellular and Molecular Life Sciences : CMLS. Aug, 2010 | Pubmed ID: 20217455 Cross-reactivity of Autoantibodies from Patients with Epidermolysis Bullosa Acquisita with Murine Collagen VII Cellular and Molecular Life Sciences : CMLS. Apr, 2010 | Pubmed ID: 20084423 T Cells Are Required for the Production of Blister-inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20038644 Pathogenicity of IgG Subclass Autoantibodies to Type VII Collagen: Induction of Dermal-epidermal Separation Journal of Autoimmunity. Jun, 2010 | Pubmed ID: 19948391 Autoimmunity Against Type VII Collagen in Inflammatory Bowel Disease Journal of Cellular and Molecular Medicine. Oct, 2010 | Pubmed ID: 19878366 Transition from Pemphigus Foliaceus to Bullous Pemphigoid: Intermolecular B-cell Epitope Spreading Without IgG Subclass Shifting Journal of the American Academy of Dermatology. Aug, 2009 | Pubmed ID: 19615544 Bullous Pemphigoid: a Prototypical Antibody-mediated Organ-specific Autoimmune Disease The Journal of Investigative Dermatology. Apr, 2009 | Pubmed ID: 19322161 Subepidermal Blistering Induced by Human Autoantibodies to BP180 Requires Innate Immune Players in a Humanized Bullous Pemphigoid Mouse Model Journal of Autoimmunity. Dec, 2008 | Pubmed ID: 18922680 Bullous Pemphigoid Autoantibodies Preferentially Recognize Phosphoepitopes in Collagen XVII The Journal of Investigative Dermatology. Nov, 2008 | Pubmed ID: 18548115 Neonatal Fc Receptor Deficiency Protects from Tissue Injury in Experimental Epidermolysis Bullosa Acquisita Journal of Molecular Medicine (Berlin, Germany). Aug, 2008 | Pubmed ID: 18542899 IgG4 Autoantibodies Induce Dermal-epidermal Separation Journal of Cellular and Molecular Medicine. Sep-Oct, 2007 | Pubmed ID: 17979887 Enzyme-linked Immunosorbent Assay Using Multimers of the 16th Non-collagenous Domain of the BP180 Antigen for Sensitive and Specific Detection of Pemphigoid Autoantibodies Experimental Dermatology. Sep, 2007 | Pubmed ID: 17697150 Immunopathology and Molecular Diagnosis of Autoimmune Bullous Diseases Journal of Cellular and Molecular Medicine. May-Jun, 2007 | Pubmed ID: 17521373 Experimental Models of Epidermolysis Bullosa Acquisita Experimental Dermatology. Jun, 2007 | Pubmed ID: 17518993 The Alternative Pathway of Complement Activation is Critical for Blister Induction in Experimental Epidermolysis Bullosa Acquisita Journal of Immunology (Baltimore, Md. : 1950). May, 2007 | Pubmed ID: 17475881 The Relevance of the IgG Subclass of Autoantibodies for Blister Induction in Autoimmune Bullous Skin Diseases Archives of Dermatological Research. Apr, 2007 | Pubmed ID: 17277959 Spatiotemporal Distribution of Fras1/Frem Proteins During Mouse Embryonic Development Gene Expression Patterns : GEP. Feb, 2007 | Pubmed ID: 17251066 IgA Pemphigus--occurrence of Anti-desmocollin 1 and Anti-desmoglein 1 Antibody Reactivity in an Individual Patient Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Dec, 2006 | Pubmed ID: 17176412 Autoantibodies from Patients with BSLE Inducing Recruitment of Leukocytes to the Dermoepidermal Junction and Subepidermal Splits in Cryosections of Human Skin Archives of Dermatology. Nov, 2006 | Pubmed ID: 17116854 Induction of Complement-fixing Autoantibodies Against Type VII Collagen Results in Subepidermal Blistering in Mice Journal of Immunology (Baltimore, Md. : 1950). Sep, 2006 | Pubmed ID: 16920988 Localisation of Bullous Pemphigoid Antigen 180 (BP180) in Cultured Human Keratinocytes: Functionally Relevant Modification by Calcium Archives of Dermatological Research. Nov, 2006 | Pubmed ID: 16906396 Generation and Characterization of Monoclonal Antibodies Against the Intracellular Domain of Hemidesmosomal Type XVII Collagen Hybridoma (2005). Jun, 2006 | Pubmed ID: 16796463 Immunoadsorption Against Two Distinct Epitopes on Human Type XVII Collagen Abolishes Dermal-epidermal Separation Induced in Vitro by Autoantibodies from Pemphigoid Gestationis Patients European Journal of Immunology. Apr, 2006 | Pubmed ID: 16552711 [Anti-laminin 5 Mucous Membrane Pemphigoid] Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Jan, 2006 | Pubmed ID: 16503930 Scarring Autoimmune Bullous Disease in a Ugandan Patient with Autoantibodies to BP180, BP230, and Laminin 5 Journal of the American Academy of Dermatology. Feb, 2006 | Pubmed ID: 16427991 [Mucous Membrane Pemphigoid: IgG and IgA Antibodies Against the BP180 Antigen] Actas Dermo-sifiliográficas. Jul-Aug, 2005 | Pubmed ID: 16476255 Mechanisms of Blister Induction by Autoantibodies Experimental Dermatology. Dec, 2005 | Pubmed ID: 16274453 IgG Autoantibodies to Type VII Collagen and an Exclusive IgG3 Reactivity to the Laminin Alpha3 Chain in a Patient with an Autoimmune Subepidermal Blistering Disease Journal of the American Academy of Dermatology. Sep, 2005 | Pubmed ID: 16112366 Subepidermal Blistering Disease with Autoantibodies to Both the P200 Autoantigen and the Alpha3 Chain of Laminin 5 Journal of the American Academy of Dermatology. May, 2005 | Pubmed ID: 15858518 Induction of Dermal-epidermal Separation in Mice by Passive Transfer of Antibodies Specific to Type VII Collagen The Journal of Clinical Investigation. Apr, 2005 | Pubmed ID: 15841176 Subclass Distribution of Type VII Collagen-specific Autoantibodies in Patients with Inflammatory Bowel Disease Journal of Dermatological Science. Mar, 2005 | Pubmed ID: 15734289 [Bullous Autoimmune Dermatoses (I): Pathogenesis and Diagnosis] Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Feb, 2004 | Pubmed ID: 16279248 [Blistering Autoimmune Dermatoses (II): Therapy] Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Sep, 2004 | Pubmed ID: 16279223 Comparative Analysis of Methods for Detection of Anti-laminin 5 Autoantibodies in Patients with Anti-epiligrin Cicatricial Pemphigoid Journal of the American Academy of Dermatology. Dec, 2004 | Pubmed ID: 15583578 Downregulation of CXCR1 and CXCR2 Expression on Human Neutrophils by Helicobacter Pylori: a New Pathomechanism in H. Pylori Infection? Infection and Immunity. Dec, 2004 | Pubmed ID: 15557597 Granulocyte-derived Elastase and Gelatinase B Are Required for Dermal-epidermal Separation Induced by Autoantibodies from Patients with Epidermolysis Bullosa Acquisita and Bullous Pemphigoid The Journal of Pathology. Dec, 2004 | Pubmed ID: 15538734 Localized Linear IgA Disease Induced by Ampicillin/sulbactam Journal of the American Academy of Dermatology. Jul, 2004 | Pubmed ID: 15243532 Development of an ELISA for the Detection of Autoantibodies to BP230 Clinical Immunology (Orlando, Fla.). Apr, 2004 | Pubmed ID: 15093564 Immunoblotting and Enzyme-linked Immunosorbent Assay for the Diagnosis of Pemphigoid Gestationis Obstetrics and Gynecology. Apr, 2004 | Pubmed ID: 15051570 The 97-kDa (LABD97) and 120-kDa (LAD-1) Fragments of Bullous Pemphigoid Antigen 180/type XVII Collagen Have Different N-termini The Journal of Investigative Dermatology. Dec, 2003 | Pubmed ID: 14675210 The Autoantigen of Anti-p200 Pemphigoid is an Acidic Noncollagenous N-linked Glycoprotein of the Cutaneous Basement Membrane The Journal of Investigative Dermatology. Dec, 2003 | Pubmed ID: 14675190 Memory B Cells Specific for the NC16A Domain of the 180 KDa Bullous Pemphigoid Autoantigen Can Be Detected in Peripheral Blood of Bullous Pemphigoid Patients and Induced in Vitro to Synthesize Autoantibodies The Journal of Investigative Dermatology. Mar, 2003 | Pubmed ID: 12603849 Autoreactive T Cell Responses in Pemphigus and Pemphigoid Autoimmunity Reviews. Oct, 2002 | Pubmed ID: 12848979 A Highly Sensitive and Simple Assay for the Detection of Circulating Autoantibodies Against Full-length Bullous Pemphigoid Antigen 180 Journal of Autoimmunity. Jun, 2002 | Pubmed ID: 12144811 Autoantibodies to Type VII Collagen Mediate Fcgamma-dependent Neutrophil Activation and Induce Dermal-epidermal Separation in Cryosections of Human Skin The American Journal of Pathology. Jul, 2002 | Pubmed ID: 12107115 Subacute Prurigo Variant of Bullous Pemphigoid: Autoantibodies Show the Same Specificity Compared with Classic Bullous Pemphigoid Journal of the American Academy of Dermatology. Jul, 2002 | Pubmed ID: 12077594 Autoantibodies to Bullous Pemphigoid Antigen 180 Induce Dermal-epidermal Separation in Cryosections of Human Skin The Journal of Investigative Dermatology. Apr, 2002 | Pubmed ID: 11918714 Cicatricial Pemphigoid Differs from Bullous Pemphigoid and Pemphigoid Gestationis Regarding the Fine Specificity of Autoantibodies to the BP180 NC16A Domain Journal of Dermatological Science. Jan, 2002 | Pubmed ID: 11916132 Granulocyte निर्भर त्वचा autoantibody प्रेरित blistering Kinga Csorba1, Sebastian Sitaru2, Cassian Sitaru1,3 1Department of Dermatology, University of Freiburg, 2Kepler High School Freiburg, 3Centre for Biological Signalling Studies (BIOSS), University of Freiburg JoVE 4250 Imunologia e Infecção
Granulocyte निर्भर त्वचा autoantibody प्रेरित blistering Kinga Csorba1, Sebastian Sitaru2, Cassian Sitaru1,3 1Department of Dermatology, University of Freiburg, 2Kepler High School Freiburg, 3Centre for Biological Signalling Studies (BIOSS), University of Freiburg JoVE 4250 Imunologia e Infecção