Christiana Ruhrberg UCL Institute of Ophthalmology University College London Biography Publications Institution JoVE Articles Christiana Ruhrberg has not added a biography. If you are Christiana Ruhrberg and would like to personalize this page please email our Author Liaison for assistance. Publications Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain Cerebral Cortex (New York, N.Y. : 1991). Jul, 2018 | Pubmed ID: 29901792 VEGF-A and Neuropilin 1 (NRP1) Shape Axon Projections in the Developing CNS Via Dual Roles in Neurons and Blood Vessels Development (Cambridge, England). 07, 2017 | Pubmed ID: 28676569 Genetic Specification of Left-right Asymmetry in the Diaphragm Muscles and Their Motor Innervation ELife. Jun, 2017 | Pubmed ID: 28639940 VEGF165-induced Vascular Permeability Requires NRP1 for ABL-mediated SRC Family Kinase Activation The Journal of Experimental Medicine. Apr, 2017 | Pubmed ID: 28289053 Regulation of Embryonic Neurogenesis by Germinal Zone Vasculature Proceedings of the National Academy of Sciences of the United States of America. Nov, 2016 | Pubmed ID: 27821771 Neuropilin-1 Mediates Vascular Permeability Independently of Vascular Endothelial Growth Factor Receptor-2 Activation Science Signaling. Apr, 2016 | Pubmed ID: 27117252 2- and 6-O-sulfated Proteoglycans Have Distinct and Complementary Roles in Cranial Axon Guidance and Motor Neuron Migration Development (Cambridge, England). 06, 2016 | Pubmed ID: 27048738 NRP1 Function and Targeting in Neurovascular Development and Eye Disease Progress in Retinal and Eye Research. 05, 2016 | Pubmed ID: 26923176 Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization--Brief Report Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2016 | Pubmed ID: 26603154 Altered Proliferative Ability of Neuronal Progenitors in PlexinA1 Mutant Mice The Journal of Comparative Neurology. Feb, 2016 | Pubmed ID: 25975775 Imatinib May Be ABL to Improve Anti-angiogenic Therapy Molecular & Cellular Oncology. Jan-Mar, 2015 | Pubmed ID: 27308396 The Embryonic Mouse Hindbrain and Postnatal Retina As In Vivo Models to Study Angiogenesis Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26285754 Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves Cell. Aug, 2015 | Pubmed ID: 26279190 Vascularisation of the Central Nervous System Mechanisms of Development. Nov, 2015 | Pubmed ID: 26222953 Suppression of β3-integrin in Mice Triggers a Neuropilin-1-dependent Change in Focal Adhesion Remodelling That Can Be Targeted to Block Pathological Angiogenesis Disease Models & Mechanisms. Sep, 2015 | Pubmed ID: 26159543 Neural Crest-derived SEMA3C Activates Endothelial NRP1 for Cardiac Outflow Tract Septation The Journal of Clinical Investigation. Jul, 2015 | Pubmed ID: 26053665 NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells Cell Reports. Jun, 2015 | Pubmed ID: 26051942 Dysfunctional SEMA3E Signaling Underlies Gonadotropin-releasing Hormone Neuron Deficiency in Kallmann Syndrome The Journal of Clinical Investigation. Jun, 2015 | Pubmed ID: 25985275 Neural Crest Cell-derived VEGF Promotes Embryonic Jaw Extension Proceedings of the National Academy of Sciences of the United States of America. May, 2015 | Pubmed ID: 25922531 Neural Crest Cells in Cardiovascular Development Current Topics in Developmental Biology. 2015 | Pubmed ID: 25662261 VEGF189 Binds NRP1 and is Sufficient for VEGF/NRP1-dependent Neuronal Patterning in the Developing Brain Development (Cambridge, England). Jan, 2015 | Pubmed ID: 25519242 The Mouse Hindbrain: an in Vivo Model to Analyze Developmental Angiogenesis Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25468597 Neuropilin Regulation of Angiogenesis Biochemical Society Transactions. Dec, 2014 | Pubmed ID: 25399580 Imatinib Inhibits VEGF-independent Angiogenesis by Targeting Neuropilin 1-dependent ABL1 Activation in Endothelial Cells The Journal of Experimental Medicine. Jun, 2014 | Pubmed ID: 24863063 Neuropilin Regulation of Angiogenesis, Arteriogenesis and Vascular Permeability Microcirculation (New York, N.Y. : 1994). Feb, 2014 | Pubmed ID: 24521511 Neuropilin 1 (NRP1) Hypomorphism Combined with Defective VEGF-A Binding Reveals Novel Roles for NRP1 in Developmental and Pathological Angiogenesis Development (Cambridge, England). Feb, 2014 | Pubmed ID: 24401374 Vascularisation is Not Necessary for Gut Colonisation by Enteric Neural Crest Cells Developmental Biology. Jan, 2014 | Pubmed ID: 24262984 The Cytoplasmic Domain of Neuropilin-1 Regulates Focal Adhesion Turnover FEBS Letters. Nov, 2013 | Pubmed ID: 24021649 The Neuropilin 1 Cytoplasmic Domain is Required for VEGF-A-dependent Arteriogenesis Developmental Cell. Apr, 2013 | Pubmed ID: 23639442 Neurovascular Development and Links to Disease Cellular and Molecular Life Sciences : CMLS. May, 2013 | Pubmed ID: 23475065 The Embryonic Mouse Hindbrain As a Qualitative and Quantitative Model for Studying the Molecular and Cellular Mechanisms of Angiogenesis Nature Protocols. Feb, 2013 | Pubmed ID: 23424750 Neuropilin Signalling in Vessels, Neurons and Tumours Seminars in Cell & Developmental Biology. Mar, 2013 | Pubmed ID: 23319134 NRP1 Acts Cell Autonomously in Endothelium to Promote Tip Cell Function During Sprouting Angiogenesis Blood. Mar, 2013 | Pubmed ID: 23315162 Emerging Roles for Semaphorins and VEGFs in Synaptogenesis and Synaptic Plasticity Cell Adhesion & Migration. Nov-Dec, 2012 | Pubmed ID: 23076132 NRP1 and NRP2 Cooperate to Regulate Gangliogenesis, Axon Guidance and Target Innervation in the Sympathetic Nervous System Developmental Biology. Sep, 2012 | Pubmed ID: 22790009 Semaphorin3A, Neuropilin-1, and PlexinA1 Are Required for Lymphatic Valve Formation Circulation Research. Aug, 2012 | Pubmed ID: 22723296 Diverse Roles for VEGF-A in the Nervous System Development (Cambridge, England). Apr, 2012 | Pubmed ID: 22434866 The Hormone of Love Attracts a Partner for Life Developmental Cell. Oct, 2011 | Pubmed ID: 22014517 The Cytoplasmic Domain of Neuropilin 1 is Dispensable for Angiogenesis, but Promotes the Spatial Separation of Retinal Arteries and Veins Development (Cambridge, England). Oct, 2011 | Pubmed ID: 21852397 Transcriptome Analysis of Embryonic Mammary Cells Reveals Insights into Mammary Lineage Establishment Breast Cancer Research : BCR. 2011 | Pubmed ID: 21834968 VEGF Signalling Controls GnRH Neuron Survival Via NRP1 Independently of KDR and Blood Vessels Development (Cambridge, England). Sep, 2011 | Pubmed ID: 21828096 VEGF Signaling Through Neuropilin 1 Guides Commissural Axon Crossing at the Optic Chiasm Neuron. Jun, 2011 | Pubmed ID: 21658587 Robo1 Regulates Semaphorin Signaling to Guide the Migration of Cortical Interneurons Through the Ventral Forebrain The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2011 | Pubmed ID: 21508241 Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair Journal of the American Society of Nephrology : JASN. Feb, 2011 | Pubmed ID: 21289217 Defective Gonadotropin-releasing Hormone Neuron Migration in Mice Lacking SEMA3A Signalling Through NRP1 and NRP2: Implications for the Aetiology of Hypogonadotropic Hypogonadism Human Molecular Genetics. Jan, 2011 | Pubmed ID: 21059704 Neuralleiste Ursprung Der Olfaktorischen Ensheathing Glia Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21078992 In the Beginning: Generating Neural Crest Cell Diversity Cell Adhesion & Migration. Oct-Dec, 2010 | Pubmed ID: 20930541 VEGF in the Nervous System Organogenesis. Apr-Jun, 2010 | Pubmed ID: 20885857 VEGF Receptor Signaling in Vertebrate Development Organogenesis. Apr-Jun, 2010 | Pubmed ID: 20885856 A Double Agent in Cancer: Deciphering Macrophage Roles in Human Tumors Nature Medicine. Aug, 2010 | Pubmed ID: 20689550 Tissue Macrophages Act As Cellular Chaperones for Vascular Anastomosis Downstream of VEGF-mediated Endothelial Tip Cell Induction Blood. Aug, 2010 | Pubmed ID: 20404134 Neuropilin, You Gotta Let Me Know: Should I Stay or Should I Go? Cell Adhesion & Migration. Jan-Mar, 2010 | Pubmed ID: 20026901 Neuropilin Ligands in Vascular and Neuronal Patterning Biochemical Society Transactions. Dec, 2009 | Pubmed ID: 19909252 Neuropilin-mediated Neural Crest Cell Guidance is Essential to Organise Sensory Neurons into Segmented Dorsal Root Ganglia Development (Cambridge, England). Jun, 2009 | Pubmed ID: 19386662 Neuropilin 1 Signaling Guides Neural Crest Cells to Coordinate Pathway Choice with Cell Specification Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19325129 Plexin A3 and Plexin A4 Convey Semaphorin Signals During Facial Nerve Development Developmental Biology. Dec, 2008 | Pubmed ID: 18804103 Angiogenesis Selectively Requires the P110alpha Isoform of PI3K to Control Endothelial Cell Migration Nature. May, 2008 | Pubmed ID: 18449193 Blood Vessel Maturation and Response to Vascular-disrupting Therapy in Single Vascular Endothelial Growth Factor-A Isoform-producing Tumors Cancer Research. Apr, 2008 | Pubmed ID: 18381437 Neuropilin 1 and 2 Control Cranial Gangliogenesis and Axon Guidance Through Neural Crest Cells Development (Cambridge, England). May, 2008 | Pubmed ID: 18356247 Role of the Neuropilin Ligands VEGF164 and SEMA3A in Neuronal and Vascular Patterning in the Mouse Novartis Foundation Symposium. 2007 | Pubmed ID: 18300426 Selective Requirements for NRP1 Ligands During Neurovascular Patterning Development (Cambridge, England). May, 2007 | Pubmed ID: 17428830 Vascular Endothelial Growth Factor Controls Neuronal Migration and Cooperates with Sema3A to Pattern Distinct Compartments of the Facial Nerve Genes & Development. Nov, 2004 | Pubmed ID: 15545635 Neuropilin-1 is Required for Endothelial Tip Cell Guidance in the Developing Central Nervous System Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2004 | Pubmed ID: 15376331 Mapping Nucleolar and Spliceosome Localization Sequences of Neuregulin1-beta3 Experimental Cell Research. Sep, 2004 | Pubmed ID: 15302578 Growing and Shaping the Vascular Tree: Multiple Roles for VEGF BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Nov, 2003 | Pubmed ID: 14579246 Neuronal Defects in the Hindbrain of Hoxa1, Hoxb1 and Hoxb2 Mutants Reflect Regulatory Interactions Among These Hox Genes Development (Cambridge, England). Dec, 2003 | Pubmed ID: 14522873 VEGF Guides Angiogenic Sprouting Utilizing Endothelial Tip Cell Filopodia The Journal of Cell Biology. Jun, 2003 | Pubmed ID: 12810700 Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport Science (New York, N.Y.). May, 2003 | Pubmed ID: 12730604 Spatially Restricted Patterning Cues Provided by Heparin-binding VEGF-A Control Blood Vessel Branching Morphogenesis Genes & Development. Oct, 2002 | Pubmed ID: 12381667 Bewertung von vaskulären Hyperpermeability-induzierende Wirkstoffe in der Haut mit dem Meilen-Assay James T. Brash1, Christiana Ruhrberg1, Alessandro Fantin1 1UCL Institute of Ophthalmology, University College London JoVE 57524 Biologia Die Maus Hinterhirn als Modell für die Erforschung embryonaler Neurogenese Mathew Tata1, Christiana Ruhrberg1 1UCL Institute of Ophthalmology JoVE 56793 Neurociência Maus-Hinterhirn Miguel Tillo1, Quenten Schwarz1,2, Christiana Ruhrberg1 1UCL Institute of Ophthalmology, University College London, 2Department of Human Immunology, Centre for Cancer Biology, South Australia JoVE 51397 Neurociência
Bewertung von vaskulären Hyperpermeability-induzierende Wirkstoffe in der Haut mit dem Meilen-Assay James T. Brash1, Christiana Ruhrberg1, Alessandro Fantin1 1UCL Institute of Ophthalmology, University College London JoVE 57524 Biologia
Die Maus Hinterhirn als Modell für die Erforschung embryonaler Neurogenese Mathew Tata1, Christiana Ruhrberg1 1UCL Institute of Ophthalmology JoVE 56793 Neurociência
Maus-Hinterhirn Miguel Tillo1, Quenten Schwarz1,2, Christiana Ruhrberg1 1UCL Institute of Ophthalmology, University College London, 2Department of Human Immunology, Centre for Cancer Biology, South Australia JoVE 51397 Neurociência