Danette L. Daniels Promega Corporation Biography Publications Institution JoVE Articles Danette L. Daniels has not added a biography. If you are Danette L. Daniels and would like to personalize this page please email our Author Liaison for assistance. Publications Selective Targeting of BD1 and BD2 of the BET Proteins in Cancer and Immunoinflammation Science (New York, N.Y.). 04, 2020 | Pubmed ID: 32193360 Non-canonical MTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism Through SIRT6-FoxO1 Molecular Cell. 08, 2019 | Pubmed ID: 31442424 Monitoring and Deciphering Protein Degradation Pathways Inside Cells Drug Discovery Today. Technologies. Apr, 2019 | Pubmed ID: 31200861 Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 As a Potent, Fast, and Selective Von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7 Journal of Medicinal Chemistry. 01, 2019 | Pubmed ID: 30540463 Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action ACS Chemical Biology. 09, 2018 | Pubmed ID: 30137962 Cross-talk Between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications Cell. 08, 2018 | Pubmed ID: 30057114 Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation ACS Chemical Biology. 10, 2017 | Pubmed ID: 28849908 Target Identification Using Cell Permeable and Cleavable Chloroalkane Derivatized Small Molecules Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28808997 Potent and Selective Bivalent Inhibitors of BET Bromodomains Nature Chemical Biology. Dec, 2016 | Pubmed ID: 27775716 SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes Molecular Cell. 10, 2016 | Pubmed ID: 27720645 The TIP60 Complex Is a Conserved Coactivator of HIF1A Cell Reports. Jun, 2016 | Pubmed ID: 27320910 Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes Cancer Research. 04, 2016 | Pubmed ID: 26837761 LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor Angewandte Chemie (Weinheim an Der Bergstrasse, Germany). May, 2015 | Pubmed ID: 27346896 Target Engagement and Drug Residence Time Can Be Observed in Living Cells with BRET Nature Communications. Dec, 2015 | Pubmed ID: 26631872 Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy Cancer Research. Dec, 2015 | Pubmed ID: 26552700 LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor Angewandte Chemie (International Ed. in English). May, 2015 | Pubmed ID: 25864491 Phosphorylation of FADD by the Kinase CK1α Promotes KRASG12D-induced Lung Cancer Science Signaling. Jan, 2015 | Pubmed ID: 25628462 KDM4A Lysine Demethylase Induces Site-specific Copy Gain and Rereplication of Regions Amplified in Tumors Cell. Aug, 2013 | Pubmed ID: 23871696 HIF1A Employs CDK8-mediator to Stimulate RNAPII Elongation in Response to Hypoxia Cell. Jun, 2013 | Pubmed ID: 23746844 Isolation of Intracellular Protein--DNA Complexes Using HaloCHIP, an Antibody-free Alternative to Chromatin Immunoprecipitation Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23436357 Development of a Dehalogenase-based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands Current Chemical Genomics. 2012 | Pubmed ID: 23248739 Examining the Complexity of Human RNA Polymerase Complexes Using HaloTag Technology Coupled to Label Free Quantitative Proteomics Journal of Proteome Research. Feb, 2012 | Pubmed ID: 22149079 HiBiT CRISPR細胞株を用いた標的タンパク質分解化合物のハイスループット細胞プロファイリング(英語) Kristin M. Riching1, Sarah D. Mahan1, Marjeta Urh1, Danette L. Daniels1 1Promega Corporation JoVE 61787 Pesquisa do câncer
HiBiT CRISPR細胞株を用いた標的タンパク質分解化合物のハイスループット細胞プロファイリング(英語) Kristin M. Riching1, Sarah D. Mahan1, Marjeta Urh1, Danette L. Daniels1 1Promega Corporation JoVE 61787 Pesquisa do câncer