David A. Wassarman Department of Medical Genetics University of Wisconsin-Madison Biography Publications Institution JoVE Articles David A. Wassarman has not added a biography. If you are David A. Wassarman and would like to personalize this page please email our Author Liaison for assistance. Publications Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly () to Ether and Non-Ether Volatile Anesthetics International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36768163 Lissencephaly-1 Mutations Enhance Traumatic Brain Injury Outcomes in Drosophila Genetics. Jan, 2023 | Pubmed ID: 36683334 Anesthetic Preconditioning of Traumatic Brain Injury Is Ineffective in a Drosophila Model of Obesity The Journal of Pharmacology and Experimental Therapeutics. Jun, 2022 | Pubmed ID: 35347062 Beta-blockers Reduce Intestinal Permeability and Early Mortality Following Traumatic Brain Injury in MicroPublication Biology. 2021 | Pubmed ID: 34723144 Ketogenic Diet Reduces Early Mortality Following Traumatic Brain Injury in Drosophila Via the PPARγ Ortholog Eip75B PloS One. 2021 | Pubmed ID: 34699541 Effects of Blunt Force Injuries in Third-instar Larvae Persist Through Metamorphosis and Reduce Adult Lifespan MicroPublication Biology. 2021 | Pubmed ID: 34278243 Survival Following Traumatic Brain Injury in Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor Relish Genetics. Dec, 2020 | Pubmed ID: 33109529 Interactions Among Genetic Background, Anesthetic Agent, and Oxygen Concentration Shape Blunt Traumatic Brain Injury Outcomes in International Journal of Molecular Sciences. Sep, 2020 | Pubmed ID: 32967238 Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity Anesthesiology. Oct, 2020 | Pubmed ID: 32773682 Loss of the Antimicrobial Peptide Metchnikowin Protects Against Traumatic Brain Injury Outcomes in G3 (Bethesda, Md.). Sep, 2020 | Pubmed ID: 32631949 Ageing and Genetic Background Influence Anaesthetic Effects in a D. melanogaster Model of Blunt Trauma with Brain Injury British Journal of Anaesthesia. Jul, 2020 | Pubmed ID: 32466842 Anesthetics Influence Mortality in a Drosophila Model of Blunt Trauma With Traumatic Brain Injury Anesthesia and Analgesia. Jun, 2018 | Pubmed ID: 29596093 Genetic Variability Affects Absolute and Relative Potencies and Kinetics of the Anesthetics Isoflurane and Sevoflurane in Drosophila Melanogaster Scientific Reports. 02, 2018 | Pubmed ID: 29402974 A Pharmacological Screen for Compounds That Rescue the Developmental Lethality of a Drosophila ATM Mutant PloS One. 2018 | Pubmed ID: 29338042 Age and Diet Affect Genetically Separable Secondary Injuries That Cause Acute Mortality Following Traumatic Brain Injury in Drosophila G3 (Bethesda, Md.). Dec, 2016 | Pubmed ID: 27754853 The Gut Reaction to Traumatic Brain Injury Fly. 2015 | Pubmed ID: 26291482 Death Following Traumatic Brain Injury in Drosophila is Associated with Intestinal Barrier Dysfunction ELife. 2015 | Pubmed ID: 25742603 A Drosophila Model of Closed Head Traumatic Brain Injury Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24127584 The Innate Immune Response Transcription Factor Relish is Necessary for Neurodegeneration in a Drosophila Model of Ataxia-telangiectasia Genetics. May, 2013 | Pubmed ID: 23502677 The Drosophila Translational Control Element (TCE) is Required for High-level Transcription of Many Genes That Are Specifically Expressed in Testes PloS One. 2012 | Pubmed ID: 22984601 Drosophila Innate Immune Response Pathways Moonlight in Neurodegeneration Fly. Jul-Sep, 2012 | Pubmed ID: 22864563 ATM Kinase Inhibition in Glial Cells Activates the Innate Immune Response and Causes Neurodegeneration in Drosophila Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22355133 The Effect of ATM Knockdown on Ionizing Radiation-induced Neuronal Cell Cycle Reentry in Drosophila Cell Cycle (Georgetown, Tex.). Jul, 2010 | Pubmed ID: 20581464 Ubiquilin Modifies TDP-43 Toxicity in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS) The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20154090 Promoting Developmental Transcription Development (Cambridge, England). Jan, 2010 | Pubmed ID: 20023156 Control of Alternative Splicing by Signal-dependent Degradation of Splicing-regulatory Proteins The Journal of Biological Chemistry. Apr, 2009 | Pubmed ID: 19218244 A DNA Damage Signal Activates and Derepresses Exon Inclusion in Drosophila TAF1 Alternative Splicing RNA (New York, N.Y.). Aug, 2008 | Pubmed ID: 18596254 Mutations in String/CDC25 Inhibit Cell Cycle Re-entry and Neurodegeneration in a Drosophila Model of Ataxia Telangiectasia Genes & Development. May, 2008 | Pubmed ID: 18408079 Cyclic Disulfides As Functional Mimics of the Histone Deacetylase Inhibitor FK-228 Tetrahedron Letters. Jun, 2007 | Pubmed ID: 18575573 Nucleolar Colocalization of TAF1 and Testis-specific TAFs During Drosophila Spermatogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2007 | Pubmed ID: 17823958 ATM and ATR Pathways Signal Alternative Splicing of Drosophila TAF1 Pre-mRNA in Response to DNA Damage Molecular and Cellular Biology. Dec, 2006 | Pubmed ID: 17030624 DNA Binding Properties of TAF1 Isoforms with Two AT-hooks The Journal of Biological Chemistry. Oct, 2006 | Pubmed ID: 16893881 TAF1 Activates Transcription by Phosphorylation of Serine 33 in Histone H2B Science (New York, N.Y.). May, 2004 | Pubmed ID: 15143281 The SIN3 Deacetylase Complex Represses Genes Encoding Mitochondrial Proteins: Implications for the Regulation of Energy Metabolism The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12865422 The SIN3/RPD3 Deacetylase Complex is Essential for G(2) Phase Cell Cycle Progression and Regulation of SMRTER Corepressor Levels Molecular and Cellular Biology. Jul, 2002 | Pubmed ID: 12077326 Localizing Transcription Factors on Chromatin by Immunofluorescence Methods (San Diego, Calif.). Jan, 2002 | Pubmed ID: 12054899 Seriel anæstesiarray til high-throughput undersøgelse af flygtige stoffer ved hjælp af Drosophila melanogaster Zachariah P. G. Olufs1, Dena Johnson-Schlitz1, David A. Wassarman2, Misha Perouansky1 1Department of Anesthesiology, University of Wisconsin-Madison, 2Department of Medical Genetics, University of Wisconsin-Madison JoVE 65144 Genética En metode til at påføre lukket hoved traumatisk hjerneskade i Rebeccah J. Katzenberger1, Carin A. Loewen2, R. Tayler Bockstruck1, Mikal A. Woods3, Barry Ganetzky2, David A. Wassarman1 1Department of Cell and Regenerative Biology, University of Wisconsin-Madison, 2Department of Genetics, University of Wisconsin-Madison, 3Department of Natural Sciences, University of Puerto Rico-Aguadilla JoVE 52905 Neurociência
Seriel anæstesiarray til high-throughput undersøgelse af flygtige stoffer ved hjælp af Drosophila melanogaster Zachariah P. G. Olufs1, Dena Johnson-Schlitz1, David A. Wassarman2, Misha Perouansky1 1Department of Anesthesiology, University of Wisconsin-Madison, 2Department of Medical Genetics, University of Wisconsin-Madison JoVE 65144 Genética
En metode til at påføre lukket hoved traumatisk hjerneskade i Rebeccah J. Katzenberger1, Carin A. Loewen2, R. Tayler Bockstruck1, Mikal A. Woods3, Barry Ganetzky2, David A. Wassarman1 1Department of Cell and Regenerative Biology, University of Wisconsin-Madison, 2Department of Genetics, University of Wisconsin-Madison, 3Department of Natural Sciences, University of Puerto Rico-Aguadilla JoVE 52905 Neurociência