Deliang Guo Department of Radiation Oncology The Ohio State University Comprehensive Cancer Center and College of Medicine Biography Publications Institution JoVE Articles Deliang Guo has not added a biography. If you are Deliang Guo and would like to personalize this page please email our Author Liaison for assistance. Publications Feedback Loop Regulation of SCAP/SREBP-1 by MiR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth Cell Reports. Aug, 2016 | Pubmed ID: 27477273 Inhibition of SOAT1 Suppresses Glioblastoma Growth Via Blocking SREBP-1-Mediated Lipogenesis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2016 | Pubmed ID: 27281560 SCAP Links Glucose to Lipid Metabolism in Cancer Cells Molecular & Cellular Oncology. 2016 | Pubmed ID: 27065222 Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth Cancer Cell. Nov, 2015 | Pubmed ID: 26555173 Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer Current Pharmaceutical Design. 2014 | Pubmed ID: 23859617 Tumor Metabolism of Malignant Gliomas Cancers. Nov, 2013 | Pubmed ID: 24217114 Lipid Metabolism Emerges As a Promising Target for Malignant Glioma Therapy CNS Oncology. May, 2013 | Pubmed ID: 24159371 The MTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-activated Glioblastomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2013 | Pubmed ID: 24030701 EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer Cell Metabolism. May, 2013 | Pubmed ID: 23707073 [Anatomic Study on Perforating Branch Flap of Medial Vastus Muscle and Its Clinical Application] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. Sep, 2012 | Pubmed ID: 23057355 Single-cell Proteomic Chip for Profiling Intracellular Signaling Pathways in Single Tumor Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22203961 Reversing Melanoma Cross-resistance to BRAF and MEK Inhibitors by Co-targeting the AKT/mTOR Pathway PloS One. 2011 | Pubmed ID: 22194965 Oncogenic EGFR Signaling Activates an MTORC2-NF-κB Pathway That Promotes Chemotherapy Resistance Cancer Discovery. Nov, 2011 | Pubmed ID: 22145100 An LXR Agonist Promotes GBM Cell Death Through Inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent Pathway Cancer Discovery. Sep, 2011 | Pubmed ID: 22059152 Activation of Src Induces Mitochondrial Localisation of De2-7EGFR (EGFRvIII) in Glioma Cells: Implications for Glucose Metabolism Journal of Cell Science. Sep, 2011 | Pubmed ID: 21878501 Combination Therapy with Vemurafenib (PLX4032/RG7204) and Metformin in Melanoma Cell Lines with Distinct Driver Mutations Journal of Translational Medicine. May, 2011 | Pubmed ID: 21609436 Differential Sensitivity of Melanoma Cell Lines with BRAFV600E Mutation to the Specific Raf Inhibitor PLX4032 Journal of Translational Medicine. Apr, 2010 | Pubmed ID: 20406486 AMPK: A Metabolic Checkpoint That Regulates the Growth of EGFR Activated Glioblastomas Cell Cycle (Georgetown, Tex.). Jan, 2010 | Pubmed ID: 20023392 EGFR Signaling Through an Akt-SREBP-1-dependent, Rapamycin-resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy Science Signaling. 2009 | Pubmed ID: 20009104 The AMPK Agonist AICAR Inhibits the Growth of EGFRvIII-expressing Glioblastomas by Inhibiting Lipogenesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19625624 Angiotensin II Up-regulates Soluble Epoxide Hydrolase in Vascular Endothelium in Vitro and in Vivo Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17495027 Regulation of Endothelial Cell Cycle by Laminar Versus Oscillatory Flow: Distinct Modes of Interactions of AMP-activated Protein Kinase and Akt Pathways Circulation Research. Mar, 2007 | Pubmed ID: 17272808 Identification and Characterization of a Novel Cytoplasm Protein ICF45 That is Involved in Cell Cycle Regulation The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15459185 Analysis of SCAP N-glycosylation and Trafficking in Human Cells Chunming Cheng1, Jeffrey Yunhua Guo1, Feng Geng1, Xiaoning Wu1, Xiang Cheng1, Qiyue Li1, Deliang Guo1 1Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine JoVE 54709 Biologia
Analysis of SCAP N-glycosylation and Trafficking in Human Cells Chunming Cheng1, Jeffrey Yunhua Guo1, Feng Geng1, Xiaoning Wu1, Xiang Cheng1, Qiyue Li1, Deliang Guo1 1Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine JoVE 54709 Biologia