Gerd Kempermann Center for Regenerative Therapies Dresden Technische Universität Dresden Biography Publications Institution JoVE Articles Gerd Kempermann has not added a biography. If you are Gerd Kempermann and would like to personalize this page please email our Author Liaison for assistance. Publications Delayed and Transient Increase of Adult Hippocampal Neurogenesis by Physical Exercise in DBA/2 Mice PloS One. 2013 | Pubmed ID: 24376750 Is Silence Golden? Effects of Auditory Stimuli and Their Absence on Adult Hippocampal Neurogenesis Brain Structure & Function. Dec, 2013 | Pubmed ID: 24292324 Neuroscience. What the Bomb Said About the Brain Science (New York, N.Y.). Jun, 2013 | Pubmed ID: 23744936 Emergence of Individuality in Genetically Identical Mice Science (New York, N.Y.). May, 2013 | Pubmed ID: 23661762 Serotonin is Required for Exercise-induced Adult Hippocampal Neurogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2013 | Pubmed ID: 23658167 An Old Test for New Neurons: Refining the Morris Water Maze to Study the Functional Relevance of Adult Hippocampal Neurogenesis Frontiers in Neuroscience. 2013 | Pubmed ID: 23653589 The α Crystallin Domain of Small Heat Shock Protein B8 (Hspb8) Acts As Survival and Differentiation Factor in Adult Hippocampal Neurogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2013 | Pubmed ID: 23536091 Prominin-1 Allows Prospective Isolation of Neural Stem Cells from the Adult Murine Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013 | Pubmed ID: 23407958 The Mammalian Adult Neurogenesis Gene Ontology (MANGO) Provides a Structural Framework for Published Information on Genes Regulating Adult Hippocampal Neurogenesis PloS One. 2012 | Pubmed ID: 23139788 New Neurons for 'survival of the Fittest' Nature Reviews. Neuroscience. Oct, 2012 | Pubmed ID: 22948073 Neuroscience. Youth Culture in the Adult Brain Science (New York, N.Y.). Mar, 2012 | Pubmed ID: 22403375 Glial Cells in Adult Neurogenesis Glia. Feb, 2012 | Pubmed ID: 22076934 Properties of Doublecortin-(DCX)-expressing Cells in the Piriform Cortex Compared to the Neurogenic Dentate Gyrus of Adult Mice PloS One. 2011 | Pubmed ID: 22022443 Adult Hippocampal Neurogenesis and Plasticity in the Infrapyramidal Bundle of the Mossy Fiber Projection: I. Co-regulation by Activity Frontiers in Neuroscience. 2011 | Pubmed ID: 21991243 Adult Hippocampal Neurogenesis and Plasticity in the Infrapyramidal Bundle of the Mossy Fiber Projection: II. Genetic Covariation and Identification of Nos1 As Linking Candidate Gene Frontiers in Neuroscience. 2011 | Pubmed ID: 21960957 A Protocol for Isolation and Enriched Monolayer Cultivation of Neural Precursor Cells from Mouse Dentate Gyrus Frontiers in Neuroscience. 2011 | Pubmed ID: 21811434 The Pessimist's and Optimist's Views of Adult Neurogenesis Cell. Jun, 2011 | Pubmed ID: 21703445 Enriched Environment and Physical Activity Reduce Microglia and Influence the Fate of NG2 Cells in the Amygdala of Adult Mice Cell and Tissue Research. Jul, 2011 | Pubmed ID: 21688212 Seven Principles in the Regulation of Adult Neurogenesis The European Journal of Neuroscience. Mar, 2011 | Pubmed ID: 21395844 The Role of Additive Neurogenesis and Synaptic Plasticity in a Hippocampal Memory Model with Grid-cell Like Input PLoS Computational Biology. 2011 | Pubmed ID: 21298080 Physical Exercise Increases Adult Neurogenesis and Telomerase Activity, and Improves Behavioral Deficits in a Mouse Model of Schizophrenia Brain, Behavior, and Immunity. Jul, 2011 | Pubmed ID: 20970493 Chronic Treatment with Melatonin Stimulates Dendrite Maturation and Complexity in Adult Hippocampal Neurogenesis of Mice Journal of Pineal Research. Jan, 2011 | Pubmed ID: 20880317 Why and How Physical Activity Promotes Experience-induced Brain Plasticity Frontiers in Neuroscience. 2010 | Pubmed ID: 21151782 Integrative Analysis of Low- and High-resolution EQTL PloS One. 2010 | Pubmed ID: 21085707 Physical Exercise Increases Notch Activity, Proliferation and Cell Cycle Exit of Type-3 Progenitor Cells in Adult Hippocampal Neurogenesis The European Journal of Neuroscience. Oct, 2010 | Pubmed ID: 20950279 Oppositional Effects of Serotonin Receptors 5-HT1a, 2, and 2c in the Regulation of Adult Hippocampal Neurogenesis Frontiers in Molecular Neuroscience. 2010 | Pubmed ID: 20721314 Commentary: Genetic News Between Ventricle and Nose (Commentary on Poon Et Al.) The European Journal of Neuroscience. Aug, 2010 | Pubmed ID: 20718852 Cannabinoid Receptor CB1 Mediates Baseline and Activity-induced Survival of New Neurons in Adult Hippocampal Neurogenesis Cell Communication and Signaling : CCS. 2010 | Pubmed ID: 20565726 LRP2 in Ependymal Cells Regulates BMP Signaling in the Adult Neurogenic Niche Journal of Cell Science. Jun, 2010 | Pubmed ID: 20460439 Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging Cell Stem Cell. May, 2010 | Pubmed ID: 20452319 Murine Features of Neurogenesis in the Human Hippocampus Across the Lifespan from 0 to 100 Years PloS One. 2010 | Pubmed ID: 20126454 Tis21 Expression Marks Not Only Populations of Neurogenic Precursor Cells but Also New Postmitotic Neurons in Adult Hippocampal Neurogenesis Cerebral Cortex (New York, N.Y. : 1991). Feb, 2010 | Pubmed ID: 19482889 Genetics of the Hippocampal Transcriptome in Mouse: a Systematic Survey and Online Neurogenomics Resource Frontiers in Neuroscience. 2009 | Pubmed ID: 20582282 Additive Effects of Physical Exercise and Environmental Enrichment on Adult Hippocampal Neurogenesis in Mice Frontiers in Neuroscience. 2009 | Pubmed ID: 20582277 Synaptic Network Activity Induces Neuronal Differentiation of Adult Hippocampal Precursor Cells Through BDNF Signaling Frontiers in Neuroscience. 2009 | Pubmed ID: 20582276 Adaptive Peripheral Immune Response Increases Proliferation of Neural Precursor Cells in the Adult Hippocampus FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2009 | Pubmed ID: 19433626 Adult-generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies PloS One. 2009 | Pubmed ID: 19421325 Melatonin Modulates Cell Survival of New Neurons in the Hippocampus of Adult Mice Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Aug, 2009 | Pubmed ID: 19421166 CD4-positive T Lymphocytes Provide a Neuroimmunological Link in the Control of Adult Hippocampal Neurogenesis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2009 | Pubmed ID: 19299695 Age Effects on the Regulation of Adult Hippocampal Neurogenesis by Physical Activity and Environmental Enrichment in the APP23 Mouse Model of Alzheimer Disease Hippocampus. Oct, 2009 | Pubmed ID: 19219917 NMDA and Benzodiazepine Receptors Have Synergistic and Antagonistic Effects on Precursor Cells in Adult Hippocampal Neurogenesis The European Journal of Neuroscience. Jan, 2009 | Pubmed ID: 19200231 Cdk5 Regulates Accurate Maturation of Newborn Granule Cells in the Adult Hippocampus PLoS Biology. Nov, 2008 | Pubmed ID: 18998770 The Antitumorigenic Response of Neural Precursors Depends on Subventricular Proliferation and Age Stem Cells (Dayton, Ohio). Nov, 2008 | Pubmed ID: 18757298 Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18614692 Mild Brain Ischemia Induces Unique Physiological Properties in Striatal Astrocytes Glia. Jul, 2008 | Pubmed ID: 18442086 Intermediate Progenitors in Adult Hippocampal Neurogenesis: Tbr2 Expression and Coordinate Regulation of Neuronal Output The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18385329 The Contribution of Failing Adult Hippocampal Neurogenesis to Psychiatric Disorders Current Opinion in Psychiatry. May, 2008 | Pubmed ID: 18382230 Sortilin-related Receptor with A-type Repeats (SORLA) Affects the Amyloid Precursor Protein-dependent Stimulation of ERK Signaling and Adult Neurogenesis The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18362153 The Neurogenic Reserve Hypothesis: What is Adult Hippocampal Neurogenesis Good For? Trends in Neurosciences. Apr, 2008 | Pubmed ID: 18329110 Physical Activity and the Regulation of Neurogenesis in the Adult and Aging Brain Neuromolecular Medicine. 2008 | Pubmed ID: 18286387 Neurogenesis in the Adult Hippocampus Cell and Tissue Research. Jan, 2008 | Pubmed ID: 17938969 Local Origin and Activity-dependent Generation of Nestin-expressing Protoplasmic Astrocytes in CA1 Brain Structure & Function. Jul, 2007 | Pubmed ID: 17717696 Selective Targeting of Adenoviral Vectors to Neural Precursor Cells in the Hippocampus of Adult Mice: New Prospects for in Situ Gene Therapy Stem Cells (Dayton, Ohio). Nov, 2007 | Pubmed ID: 17641242 Enriched Monolayer Precursor Cell Cultures from Micro-dissected Adult Mouse Dentate Gyrus Yield Functional Granule Cell-like Neurons PloS One. 2007 | Pubmed ID: 17460755 Adult Hippocampal Neurogenesis and Aging European Archives of Psychiatry and Clinical Neuroscience. Aug, 2007 | Pubmed ID: 17401726 Two Genetic Rat Models of Arterial Hypertension Show Different Mechanisms by Which Adult Hippocampal Neurogenesis is Increased Developmental Neuroscience. 2007 | Pubmed ID: 17148955 Adult Neurogenesis and Neurodegenerative Disease Regenerative Medicine. Jan, 2006 | Pubmed ID: 17465817 They Are Not Too Excited: the Possible Role of Adult-born Neurons in Epilepsy Neuron. Dec, 2006 | Pubmed ID: 17178397 Variability of Doublecortin-associated Dendrite Maturation in Adult Hippocampal Neurogenesis is Independent of the Regulation of Precursor Cell Proliferation BMC Neuroscience. 2006 | Pubmed ID: 17105671 Type-2 Cells As Link Between Glial and Neuronal Lineage in Adult Hippocampal Neurogenesis Glia. Dec, 2006 | Pubmed ID: 16958090 Role of Endogenous Neural Stem Cells in Neurological Disease and Brain Repair Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 16955712 Cognitive and Physical Activity Differently Modulate Disease Progression in the Amyloid Precursor Protein (APP)-23 Model of Alzheimer's Disease Biological Psychiatry. Dec, 2006 | Pubmed ID: 16806094 Temporal and Spatial Dynamics of Brain Structure Changes During Extensive Learning The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16763039 Running in Pregnancy Transiently Increases Postnatal Hippocampal Neurogenesis in the Offspring Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537457 A Functional Hypothesis for Adult Hippocampal Neurogenesis: Avoidance of Catastrophic Interference in the Dentate Gyrus Hippocampus. 2006 | Pubmed ID: 16435309 Natural Variation and Genetic Covariance in Adult Hippocampal Neurogenesis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16407118 Enriched Environment Induces Cellular Plasticity in the Adult Substantia Nigra and Improves Motor Behavior Function in the 6-OHDA Rat Model of Parkinson's Disease Experimental Neurology. Jun, 2006 | Pubmed ID: 16360152 Physical Exercise Prevents Age-related Decline in Precursor Cell Activity in the Mouse Dentate Gyrus Neurobiology of Aging. Oct, 2006 | Pubmed ID: 16271278 Proliferative Response of Distinct Hippocampal Progenitor Cell Populations After Cortical Infarcts in the Adult Brain Neurobiology of Disease. Feb, 2006 | Pubmed ID: 16137890 New Neurons in the Adult Mammalian Brain: Synaptogenesis and Functional Integration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2005 | Pubmed ID: 16280573 Seizures Induce Proliferation and Dispersion of Doublecortin-positive Hippocampal Progenitor Cells Experimental Neurology. Dec, 2005 | Pubmed ID: 16168988 Nestin-expressing Cells Divide and Adopt a Complex Electrophysiologic Phenotype After Transient Brain Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Dec, 2005 | Pubmed ID: 15959463 Adult Neurogenesis and Repair of the Adult CNS with Neural Progenitors, Precursors, and Stem Cells Progress in Neurobiology. Apr, 2005 | Pubmed ID: 15913880 A Subpopulation of Precursor Cells in the Mouse Dentate Gyrus Receives Synaptic GABAergic Input Molecular and Cellular Neurosciences. Jun, 2005 | Pubmed ID: 15911343 Glioblastoma-induced Attraction of Endogenous Neural Precursor Cells is Associated with Improved Survival The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15758174 Age-dependent Expression of Glucocorticoid- and Mineralocorticoid Receptors on Neural Precursor Cell Populations in the Adult Murine Hippocampus Aging Cell. Dec, 2004 | Pubmed ID: 15569353 The Collaborative Cross, a Community Resource for the Genetic Analysis of Complex Traits Nature Genetics. Nov, 2004 | Pubmed ID: 15514660 Milestones of Neuronal Development in the Adult Hippocampus Trends in Neurosciences. Aug, 2004 | Pubmed ID: 15271491 Functional Significance of Adult Neurogenesis Current Opinion in Neurobiology. Apr, 2004 | Pubmed ID: 15082323 Adult Hippocampal Neurogenesis and Voluntary Running Activity: Circadian and Dose-dependent Effects Journal of Neuroscience Research. Apr, 2004 | Pubmed ID: 15048919 Differential Regulation of Gliogenesis in the Context of Adult Hippocampal Neurogenesis in Mice Glia. Apr, 2004 | Pubmed ID: 14999812 Transient Calretinin Expression Defines Early Postmitotic Step of Neuronal Differentiation in Adult Hippocampal Neurogenesis of Mice Molecular and Cellular Neurosciences. Nov, 2003 | Pubmed ID: 14664811 Neuroscience. Microglia: the Enemy Within? Science (New York, N.Y.). Dec, 2003 | Pubmed ID: 14657479 Adult-born Hippocampal Neurons Mature into Activity-dependent Responsiveness The European Journal of Neuroscience. Nov, 2003 | Pubmed ID: 14656319 The Nature and Identification of Quantitative Trait Loci: a Community's View Nature Reviews. Genetics. Nov, 2003 | Pubmed ID: 14634638 Subpopulations of Proliferating Cells of the Adult Hippocampus Respond Differently to Physiologic Neurogenic Stimuli The Journal of Comparative Neurology. Dec, 2003 | Pubmed ID: 14624480 Depressed New Neurons--adult Hippocampal Neurogenesis and a Cellular Plasticity Hypothesis of Major Depression Biological Psychiatry. Sep, 2003 | Pubmed ID: 12946878 Regional Effects of Wheel Running and Environmental Enrichment on Cell Genesis and Microglia Proliferation in the Adult Murine Neocortex Cerebral Cortex (New York, N.Y. : 1991). Aug, 2003 | Pubmed ID: 12853371 Subpopulation of Nestin-expressing Progenitor Cells in the Adult Murine Hippocampus Shows Electrophysiological and Morphological Characteristics of Astrocytes Molecular and Cellular Neurosciences. Jul, 2003 | Pubmed ID: 12837622 Enriched Environment and Physical Activity Stimulate Hippocampal but Not Olfactory Bulb Neurogenesis The European Journal of Neuroscience. May, 2003 | Pubmed ID: 12786970 Early Determination and Long-term Persistence of Adult-generated New Neurons in the Hippocampus of Mice Development (Cambridge, England). Jan, 2003 | Pubmed ID: 12466205 Neuroplasticity in Old Age: Sustained Fivefold Induction of Hippocampal Neurogenesis by Long-term Environmental Enrichment Annals of Neurology. Aug, 2002 | Pubmed ID: 12210782 Regulation of Adult Hippocampal Neurogenesis - Implications for Novel Theories of Major Depression Bipolar Disorders. Feb, 2002 | Pubmed ID: 12047492 Genetic Influence on Phenotypic Differentiation in Adult Hippocampal Neurogenesis Brain Research. Developmental Brain Research. Mar, 2002 | Pubmed ID: 11947932 Why New Neurons? Possible Functions for Adult Hippocampal Neurogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2002 | Pubmed ID: 11826092 One Mouse, Two Cultures: Isolation and Culture of Adult Neural Stem Cells from the Two Neurogenic Zones of Individual Mice Tara L. Walker1, Gerd Kempermann1,2 1Center for Regenerative Therapies Dresden, Technische Universität Dresden, 2German Center for Neurodegenerative Diseases (DZNE) Dresden JoVE 51225 Neurociência
One Mouse, Two Cultures: Isolation and Culture of Adult Neural Stem Cells from the Two Neurogenic Zones of Individual Mice Tara L. Walker1, Gerd Kempermann1,2 1Center for Regenerative Therapies Dresden, Technische Universität Dresden, 2German Center for Neurodegenerative Diseases (DZNE) Dresden JoVE 51225 Neurociência