Gerrit Borchard Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO) University of Geneva Biography Publications Institution JoVE Articles Gerrit Borchard has not added a biography. If you are Gerrit Borchard and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles ACS Nano. Jun, 2023 | Pubmed ID: 37379064 HDACIs and TKIs Combinations and Their Liposomal Delivery for Cancer Treatment Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2023 | Pubmed ID: 37037270 Meeting Vaccine Formulation Challenges in an Emergency Setting: Towards the Development of Accessible Vaccines Pharmacological Research. Mar, 2023 | Pubmed ID: 36796463 Structure-activity Relationship of a Peptide Permeation Enhancer Tissue Barriers. Jan, 2023 | Pubmed ID: 35369830 Characterization Challenges of Self-Assembled Polymer-SPIONs Nanoparticles: Benefits of Orthogonal Methods International Journal of Molecular Sciences. Dec, 2022 | Pubmed ID: 36555765 Impact of Peptide Permeation Enhancer on Tight Junctions Opening Cellular Mechanisms Biochemistry and Biophysics Reports. Dec, 2022 | Pubmed ID: 36324528 Characterization of the Interaction of Polymeric Micelles with SiRNA: A Combined Experimental and Molecular Dynamics Study Polymers. Oct, 2022 | Pubmed ID: 36297986 Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold Tumors Pharmaceutics. Sep, 2022 | Pubmed ID: 36145631 Regulatory Safety Evaluation of Nanomedical Products: Key Issues to Refine Drug Delivery and Translational Research. Sep, 2022 | Pubmed ID: 35908133 Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters Pharmaceutics. Jul, 2022 | Pubmed ID: 35890321 Need for Expansion of Pharmacy Education Globally for the Growing Field of Nanomedicine Pharmacy (Basel, Switzerland). Jan, 2022 | Pubmed ID: 35202067 Synergistic Effects of Antimicrobial Peptide Dendrimer-chitosan Polymer Conjugates Against Pseudomonas Aeruginosa Carbohydrate Polymers. Mar, 2022 | Pubmed ID: 35027127 DNA Vaccine Administered by Cationic Lipoplexes or by In Vivo Electroporation Induces Comparable Antibody Responses Against SARS-CoV-2 in Mice Vaccines. Aug, 2021 | Pubmed ID: 34451998 A Pragmatic Regulatory Approach for Complex Generics Through the U.S. FDA 505(j) or 505(b)(2) Approval Pathways Annals of the New York Academy of Sciences. Oct, 2021 | Pubmed ID: 34296458 Better Pandemic Influenza Preparedness Through Adjuvant Technology Transfer: Challenges and Lessons Learned Vaccines. May, 2021 | Pubmed ID: 34063131 Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure Pharmaceuticals (Basel, Switzerland). Mar, 2021 | Pubmed ID: 33800588 Target Specific Tight Junction Modulators Advanced Drug Delivery Reviews. Apr, 2021 | Pubmed ID: 33617902 Short Peptide Sequence Enhances Epithelial Permeability Through Interaction with Protein Kinase C European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. May, 2021 | Pubmed ID: 33582284 An Update on Antimicrobial Peptides (AMPs) and Their Delivery Strategies for Wound Infections Pharmaceutics. Sep, 2020 | Pubmed ID: 32887353 Are Antimicrobial Peptide Dendrimers an Escape from ESKAPE? Advances in Wound Care. May, 2020 | Pubmed ID: 32320368 How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32211394 Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32154232 Factors Influencing Safety and Efficacy of Intravenous Iron-carbohydrate Nanomedicines: From Production to Clinical Practice Nanomedicine : Nanotechnology, Biology, and Medicine. Jun, 2020 | Pubmed ID: 32145382 Iron Polymaltose Complexes: Could We Spot Physicochemical Differences in Medicines Sharing the Same Active Pharmaceutical Ingredient? European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Feb, 2020 | Pubmed ID: 31841697 Hazard Assessment of Polymeric Nanobiomaterials for Drug Delivery: What Can We Learn From Literature So Far Frontiers in Bioengineering and Biotechnology. 2019 | Pubmed ID: 31709243 Molecular Modeling for Nanomaterial-Biology Interactions: Opportunities, Challenges, and Perspectives Frontiers in Bioengineering and Biotechnology. 2019 | Pubmed ID: 31681746 Impact of Covalently Nile Red and Covalently Rhodamine Labeled Fluorescent Polymer Micelles for the Improved Imaging of the Respective Drug Delivery System European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Sep, 2019 | Pubmed ID: 31336183 Polyelectrolyte Nanocomplexes Based on Chitosan Derivatives for Wound Healing Application European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Jul, 2019 | Pubmed ID: 31085312 Nanomedicines in Clinical Practice: Are Colloidal Iron Sucrose Ready-to-use Intravenous Solutions Interchangeable? European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Apr, 2019 | Pubmed ID: 30742979 Differences Between Intravenous Iron Products: Focus on Treatment of Iron Deficiency in Chronic Heart Failure Patients ESC Heart Failure. Apr, 2019 | Pubmed ID: 30694615 Nanomedicines: The Magic Bullets Reaching Their Target? European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Feb, 2019 | Pubmed ID: 30465818 In Vitro Models for Immunogenicity Prediction of Therapeutic Proteins European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Sep, 2018 | Pubmed ID: 29894817 Hydrogels in Three-dimensional Dendritic Cell (MUTZ-3) Culture As a Scaffold to Mimic Human Immuno Competent Subcutaneous Tissue International Journal of Pharmaceutics. Jun, 2018 | Pubmed ID: 29698823 A Robust and Easily Reproducible Protocol for the Determination of Size and Size Distribution of Iron Sucrose Using Dynamic Light Scattering Journal of Pharmaceutical and Biomedical Analysis. Apr, 2018 | Pubmed ID: 29414023 Cellular Interaction and Tumoral Penetration Properties of Cyclodextrin Nanoparticles on 3D Breast Tumor Model Nanomaterials (Basel, Switzerland). Jan, 2018 | Pubmed ID: 29373490 Adjuvant Activity of Poly-ε-caprolactone/Chitosan Nanoparticles Characterized by Mast Cell Activation and IFN-γ and IL-17 Production Molecular Pharmaceutics. Jan, 2018 | Pubmed ID: 29160080 Mapping of Drug Distribution in the Rabbit Liver Tumor Model by Complementary Fluorescence and Mass Spectrometry Imaging Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2018 | Pubmed ID: 29101054 Iron Sucrose: Assessing the Similarity Between the Originator Drug and Its Intended Copies Annals of the New York Academy of Sciences. Nov, 2017 | Pubmed ID: 29168243 Free Energy Landscape of SiRNA-polycation Complexation: Elucidating the Effect of Molecular Geometry, Polymer Flexibility, and Charge Neutralization PloS One. 2017 | Pubmed ID: 29088239 Poly-ϵ-caprolactone/chitosan Nanoparticles Provide Strong Adjuvant Effect for Hepatitis B Antigen Nanomedicine (London, England). Oct, 2017 | Pubmed ID: 28868964 Drug-eluting Embolic Microspheres for Local Drug Delivery - State of the Art Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2017 | Pubmed ID: 28710006 Equivalence of Complex Drug Products: Advances in and Challenges for Current Regulatory Frameworks Annals of the New York Academy of Sciences. Nov, 2017 | Pubmed ID: 28445611 Ag85A DNA Vaccine Delivery by Nanoparticles: Influence of the Formulation Characteristics on Immune Responses Vaccines. Sep, 2016 | Pubmed ID: 27626449 Non-covalent Modification of Granulocyte-colony Stimulating Factor (G-CSF) by Coiled-coil Technology International Journal of Pharmaceutics. Sep, 2016 | Pubmed ID: 27363936 Immune Response Elicited by an Intranasally Delivered HBsAg Low-dose Adsorbed to Poly-ε-caprolactone Based Nanoparticles International Journal of Pharmaceutics. May, 2016 | Pubmed ID: 26976502 Peptide-decorated Chitosan Derivatives Enhance Fibroblast Adhesion and Proliferation in Wound Healing Carbohydrate Polymers. May, 2016 | Pubmed ID: 26917381 Arming Embolic Beads with Anti-VEGF Antibodies and Controlling Their Release Using LbL Technology Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2016 | Pubmed ID: 26780173 Characterization of PDNA-TMC Nanoparticle Interaction and Stability Current Drug Delivery. 2016 | Pubmed ID: 26638979 Noncovalent PEGylation, An Innovative Subchapter in the Field of Protein Modification Journal of Pharmaceutical Sciences. Feb, 2016 | Pubmed ID: 26523632 Sustained Protein Release from Hydrogel Microparticles Using Layer-by-layer (LbL) Technology Drug Delivery. Oct, 2016 | Pubmed ID: 26289209 Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release Nanomaterials (Basel, Switzerland). Dec, 2015 | Pubmed ID: 28347123 Chitosan As a Starting Material for Wound Healing Applications European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Nov, 2015 | Pubmed ID: 26614560 Novel Layer-by-Layer Deposition Technique for the Preparation of Double-Chambered Nanoparticle Formulations Journal of Pharmaceutical Sciences. Aug, 2015 | Pubmed ID: 26017561 Establishment and First Characterization of a Sublingual Epithelial and Immune Cell Co-culture Model International Journal of Pharmaceutics. Mar, 2015 | Pubmed ID: 25448555 Sunitinib-eluting Beads for Chemoembolization: Methods for in Vitro Evaluation of Drug Release International Journal of Pharmaceutics. Mar, 2015 | Pubmed ID: 25448554 Toll-like Receptor 2 Regulates the Barrier Function of Human Bronchial Epithelial Monolayers Through Atypical Protein Kinase C Zeta, and an Increase in Expression of Claudin-1 Tissue Barriers. 2014 | Pubmed ID: 25101232 Drug-eluting Beads Loaded with Antiangiogenic Agents for Chemoembolization: in Vitro Sunitinib Loading and Release and in Vivo Pharmacokinetics in an Animal Model Journal of Vascular and Interventional Radiology : JVIR. Mar, 2014 | Pubmed ID: 24468044 Fate of TLR-1/TLR-2 Agonist Functionalised PDNA Nanoparticles Upon Deposition at the Human Bronchial Epithelium in Vitro Journal of Nanobiotechnology. Aug, 2013 | Pubmed ID: 23964697 Multifunctional PLGA-based Nanoparticles Encapsulating Simultaneously Hydrophilic Antigen and Hydrophobic Immunomodulator for Mucosal Immunization Molecular Pharmaceutics. Aug, 2013 | Pubmed ID: 23869898 Recent Advances in Mucosal Immunization Using Virus-like Particles Molecular Pharmaceutics. May, 2013 | Pubmed ID: 23548071 Validation of a New 96-well Plate Spectrophotometric Method for the Quantification of Compound 48/80 Associated with Particles AAPS PharmSciTech. Jun, 2013 | Pubmed ID: 23468340 Preparation and Evaluation of Nanoparticles for Directed Tissue Engineering International Journal of Pharmaceutics. Dec, 2012 | Pubmed ID: 23046666 Nanoparticle Iron Medicinal Products - Requirements for Approval of Intended Copies of Non-biological Complex Drugs (NBCD) and the Importance of Clinical Comparative Studies Regulatory Toxicology and Pharmacology : RTP. Nov, 2012 | Pubmed ID: 22951348 In Vitro Evaluation of an RGD-functionalized Chitosan Derivative for Enhanced Cell Adhesion Carbohydrate Polymers. Nov, 2012 | Pubmed ID: 22944407 The School of Pharmacy Geneva-Lausanne (EPGL) - the First Ten Years Chimia. 2012 | Pubmed ID: 22867535 Noncovalent PEGylation: Different Effects of Dansyl-, L-tryptophan-, Phenylbutylamino-, Benzyl- and Cholesteryl-PEGs on the Aggregation of Salmon Calcitonin and Lysozyme Journal of Pharmaceutical Sciences. Jun, 2012 | Pubmed ID: 22447529 Toll-like Receptor-7 Agonist Decoration Enhances the Adjuvanticity of Chitosan-DNA Nanoparticles Journal of Pharmaceutical Sciences. Mar, 2012 | Pubmed ID: 22190381 Tryptophan-mPEGs: Novel Excipients That Stabilize Salmon Calcitonin Against Aggregation by Non-covalent PEGylation European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Nov, 2011 | Pubmed ID: 21703347 Noncovalent Pegylation by Dansyl-poly(ethylene Glycol)s As a New Means Against Aggregation of Salmon Calcitonin Journal of Pharmaceutical Sciences. May, 2011 | Pubmed ID: 21374604 Stimulation of Human Macrophages (THP-1) Using Toll-like Receptor-2 (TLR-2) Agonist Decorated Nanocarriers Journal of Drug Targeting. Sep, 2009 | Pubmed ID: 19694614 Análisis dinámico de dispersión de luz para la determinación del tamaño de partícula de complejos hierro-carbohidratos Michael Burgert1, Cintia Baptista Marques2, Gerrit Borchard2, Erik Philipp1, Maria Wilhelm1, Amy Alston1, Reinaldo Digigow1 1Vifor Pharma Group, Vifor Pharma Management Ltd, 2Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva JoVE 63820 Medicina
Análisis dinámico de dispersión de luz para la determinación del tamaño de partícula de complejos hierro-carbohidratos Michael Burgert1, Cintia Baptista Marques2, Gerrit Borchard2, Erik Philipp1, Maria Wilhelm1, Amy Alston1, Reinaldo Digigow1 1Vifor Pharma Group, Vifor Pharma Management Ltd, 2Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva JoVE 63820 Medicina