Graham Hatfull Department of Biological Sciences University of Pittsburgh Biography Publications Institution JoVE Articles Graham Hatfull has not added a biography. If you are Graham Hatfull and would like to personalize this page please email our Author Liaison for assistance. Publications Complete Genome Sequences of 138 Mycobacteriophages Journal of Virology. Feb, 2012 | Pubmed ID: 22282335 2GFP10: A High-intensity Fluorophage Enables Detection and Rapid Drug Susceptibility Testing of Mycobacterium Tuberculosis Directly from Sputum Samples Journal of Clinical Microbiology. Jan, 2012 | Pubmed ID: 22278833 The Bxb1 Gp47 Recombination Directionality Factor is Required Not Only for Prophage Excision, but Also for Phage DNA Replication Gene. Mar, 2012 | Pubmed ID: 22227494 Competencies: a Cure for Pre-med Curriculum Science (New York, N.Y.). Nov, 2011 | Pubmed ID: 22076362 Cluster K Mycobacteriophages: Insights into the Evolutionary Origins of Mycobacteriophage TM4 PloS One. 2011 | Pubmed ID: 22053209 Bacteriophages and Their Genomes Current Opinion in Virology. Oct, 2011 | Pubmed ID: 22034588 Reporter Phage and Breath Tests: Emerging Phenotypic Assays for Diagnosing Active Tuberculosis, Antibiotic Resistance, and Treatment Efficacy The Journal of Infectious Diseases. Nov, 2011 | Pubmed ID: 21996696 Phamerator: a Bioinformatic Tool for Comparative Bacteriophage Genomics BMC Bioinformatics. 2011 | Pubmed ID: 21991981 Evaluation of a Transposase Protocol for Rapid Generation of Shotgun High-throughput Sequencing Libraries from Nanogram Quantities of DNA Applied and Environmental Microbiology. Nov, 2011 | Pubmed ID: 21948828 Successive and Targeted DNA Integrations in the Drosophila Genome by Bxb1 and PhiC31 Integrases Genetics. Sep, 2011 | Pubmed ID: 21652525 Single-molecule Analysis Reveals the Molecular Bearing Mechanism of DNA Strand Exchange by a Serine Recombinase Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21502527 Evaluation of Fluoromycobacteriophages for Detecting Drug Resistance in Mycobacterium Tuberculosis Journal of Clinical Microbiology. May, 2011 | Pubmed ID: 21346042 Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution PloS One. 2011 | Pubmed ID: 21298013 Mycobacteriophages: Genes and Genomes Annual Review of Microbiology. 2010 | Pubmed ID: 20528690 Temperature-dependent Regulation of Mycolic Acid Cyclopropanation in Saprophytic Mycobacteria: Role of the Mycobacterium Smegmatis 1351 Gene (MSMEG_1351) in CIS-cyclopropanation of Alpha-mycolates The Journal of Biological Chemistry. Jul, 2010 | Pubmed ID: 20457615 Enzymatic Hydrolysis of Trehalose Dimycolate Releases Free Mycolic Acids During Mycobacterial Growth in Biofilms The Journal of Biological Chemistry. Jun, 2010 | Pubmed ID: 20375425 Do Mycobacteria Produce Endospores? Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080769 Comparative Genomic Analysis of 60 Mycobacteriophage Genomes: Genome Clustering, Gene Acquisition, and Gene Size Journal of Molecular Biology. Mar, 2010 | Pubmed ID: 20064525 Mycobacteriophages BPs, Angel and Halo: Comparative Genomics Reveals a Novel Class of Ultra-small Mobile Genetic Elements Microbiology (Reading, England). Sep, 2009 | Pubmed ID: 19556295 Mycobacteriophage Lysin B is a Novel Mycolylarabinogalactan Esterase Molecular Microbiology. Aug, 2009 | Pubmed ID: 19555454 Fluoromycobacteriophages for Rapid, Specific, and Sensitive Antibiotic Susceptibility Testing of Mycobacterium Tuberculosis PloS One. 2009 | Pubmed ID: 19300517 The Genome of Bacillus Subtilis Bacteriophage SPO1 Journal of Molecular Biology. Apr, 2009 | Pubmed ID: 19285085 BRED: a Simple and Powerful Tool for Constructing Mutant and Recombinant Bacteriophage Genomes PloS One. 2008 | Pubmed ID: 19088849 Recombineering Mycobacteria and Their Phages Nature Reviews. Microbiology. Nov, 2008 | Pubmed ID: 18923412 Bacteriophage Genomics Current Opinion in Microbiology. Oct, 2008 | Pubmed ID: 18824125 Comparative Genomics of the Mycobacteriophages: Insights into Bacteriophage Evolution Research in Microbiology. Jun, 2008 | Pubmed ID: 18653319 Exploring the Prokaryotic Virosphere Research in Microbiology. Jun, 2008 | Pubmed ID: 18639443 Growth of Mycobacterium Tuberculosis Biofilms Containing Free Mycolic Acids and Harbouring Drug-tolerant Bacteria Molecular Microbiology. Jul, 2008 | Pubmed ID: 18466296 Mycobacterial Recombineering Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370078 Two-step Site Selection for Serine-integrase-mediated Excision: DNA-directed Integrase Conformation and Central Dinucleotide Proofreading Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18299577 Efficient Point Mutagenesis in Mycobacteria Using Single-stranded DNA Recombineering: Characterization of Antimycobacterial Drug Targets Molecular Microbiology. Mar, 2008 | Pubmed ID: 18221264 Genomic Characterization of Mycobacteriophage Giles: Evidence for Phage Acquisition of Host DNA by Illegitimate Recombination Journal of Bacteriology. Mar, 2008 | Pubmed ID: 18178732 The Role of Iron in Mycobacterium Smegmatis Biofilm Formation: the Exochelin Siderophore is Essential in Limiting Iron Conditions for Biofilm Formation but Not for Planktonic Growth Molecular Microbiology. Oct, 2007 | Pubmed ID: 17854402 Comparative Genomic Analysis of Mycobacteriophage Tweety: Evolutionary Insights and Construction of Compatible Site-specific Integration Vectors for Mycobacteria Microbiology (Reading, England). Aug, 2007 | Pubmed ID: 17660435 Genomic and Structural Analysis of Syn9, a Cyanophage Infecting Marine Prochlorococcus and Synechococcus Environmental Microbiology. Jul, 2007 | Pubmed ID: 17564603 Genome Sequence, Structural Proteins, and Capsid Organization of the Cyanophage Syn5: a "horned" Bacteriophage of Marine Synechococcus Journal of Molecular Biology. May, 2007 | Pubmed ID: 17383677 Recombineering in Mycobacterium Tuberculosis Nature Methods. Feb, 2007 | Pubmed ID: 17179933 Inquiry Learning. Teaching Scientific Inquiry Science (New York, N.Y.). Dec, 2006 | Pubmed ID: 17185586 A Peptidoglycan Hydrolase Motif Within the Mycobacteriophage TM4 Tape Measure Protein Promotes Efficient Infection of Stationary Phase Cells Molecular Microbiology. Dec, 2006 | Pubmed ID: 17083467 Mycobacteriophage Exploit NHEJ to Facilitate Genome Circularization Molecular Cell. Sep, 2006 | Pubmed ID: 16949369 Efficient Site-specific Integration in Plasmodium Falciparum Chromosomes Mediated by Mycobacteriophage Bxb1 Integrase Nature Methods. Aug, 2006 | Pubmed ID: 16862136 Exploring the Mycobacteriophage Metaproteome: Phage Genomics As an Educational Platform PLoS Genetics. Jun, 2006 | Pubmed ID: 16789831 Control of Phage Bxb1 Excision by a Novel Recombination Directionality Factor PLoS Biology. Jun, 2006 | Pubmed ID: 16719562 GroEL1: a Dedicated Chaperone Involved in Mycolic Acid Biosynthesis During Biofilm Formation in Mycobacteria Cell. Dec, 2005 | Pubmed ID: 16325580 Synapsis in Phage Bxb1 Integration: Selection Mechanism for the Correct Pair of Recombination Sites Journal of Molecular Biology. Jun, 2005 | Pubmed ID: 15890199 Integration and Excision by the Large Serine Recombinase PhiRv1 Integrase Molecular Microbiology. Mar, 2005 | Pubmed ID: 15752208 2004 ASM Conference on the New Phage Biology: the 'Phage Summit' Molecular Microbiology. Mar, 2005 | Pubmed ID: 15720541 The Generalized Transducing Salmonella Bacteriophage ES18: Complete Genome Sequence and DNA Packaging Strategy Journal of Bacteriology. Feb, 2005 | Pubmed ID: 15659686 Bxz1, a New Generalized Transducing Phage for Mycobacteria FEMS Microbiology Letters. Dec, 2004 | Pubmed ID: 15598543 Complete Genomic Sequence of the Virulent Salmonella Bacteriophage SP6 Journal of Bacteriology. Apr, 2004 | Pubmed ID: 15028677 The PKO2 Linear Plasmid Prophage of Klebsiella Oxytoca Journal of Bacteriology. Mar, 2004 | Pubmed ID: 14996813 The Orientation of Mycobacteriophage Bxb1 Integration is Solely Dependent on the Central Dinucleotide of AttP and AttB Molecular Cell. Nov, 2003 | Pubmed ID: 14636570 Mycobacteriophage Bxb1 Integrates into the Mycobacterium Smegmatis GroEL1 Gene Molecular Microbiology. Oct, 2003 | Pubmed ID: 14617171 Rapid Identification and Susceptibility Testing of Mycobacterium Tuberculosis from MGIT Cultures with Luciferase Reporter Mycobacteriophages Journal of Medical Microbiology. Jul, 2003 | Pubmed ID: 12808076 Bacteriophages with Tails: Chasing Their Origins and Evolution Research in Microbiology. May, 2003 | Pubmed ID: 12798229 Origins of Highly Mosaic Mycobacteriophage Genomes Cell. Apr, 2003 | Pubmed ID: 12705866 Control of Directionality in L5 Integrase-mediated Site-specific Recombination Journal of Molecular Biology. Feb, 2003 | Pubmed ID: 12581642 Corrected Sequence of the Bacteriophage P22 Genome Journal of Bacteriology. Feb, 2003 | Pubmed ID: 12562822 Specialized Transduction: an Efficient Method for Generating Marked and Unmarked Targeted Gene Disruptions in Mycobacterium Tuberculosis, M. Bovis BCG and M. Smegmatis Microbiology (Reading, England). Oct, 2002 | Pubmed ID: 12368434 Integration and Excision of the Mycobacterium Tuberculosis Prophage-like Element, PhiRv1 Molecular Microbiology. Sep, 2002 | Pubmed ID: 12354222 Imbroglios of Viral Taxonomy: Genetic Exchange and Failings of Phenetic Approaches Journal of Bacteriology. Sep, 2002 | Pubmed ID: 12169615 Bacteriophage Mu Genome Sequence: Analysis and Comparison with Mu-like Prophages in Haemophilus, Neisseria and Deinococcus Journal of Molecular Biology. Mar, 2002 | Pubmed ID: 11922669 Microbiology. A Tail of Two Specifi-cities Science (New York, N.Y.). Mar, 2002 | Pubmed ID: 11896263 نمو المتفطرة السلية الأغشية الحيوية Kathleen Kulka1, Graham Hatfull2, Anil K. Ojha1 1Department of Infectious Diseases and Microbiology, University of Pittsburgh, 2Department of Biological Sciences, University of Pittsburgh JoVE 3820 Imunologia e Infecção
نمو المتفطرة السلية الأغشية الحيوية Kathleen Kulka1, Graham Hatfull2, Anil K. Ojha1 1Department of Infectious Diseases and Microbiology, University of Pittsburgh, 2Department of Biological Sciences, University of Pittsburgh JoVE 3820 Imunologia e Infecção