Grant A. Ramm Hepatic Fibrosis Group QIMR Berghofer Medical Research Institute Biography Publications Institution JoVE Articles Grant A. Ramm has not added a biography. If you are Grant A. Ramm and would like to personalize this page please email our Author Liaison for assistance. Publications Utility of Hepatic or Total Body Iron Burden in the Assessment of Advanced Hepatic Fibrosis in HFE Hemochromatosis Scientific Reports. Dec, 2019 | Pubmed ID: 31882912 Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Oct, 2019 | Pubmed ID: 31622736 Supersonic Shear-wave Elastography and APRI for the Detection and Staging of Liver Disease in Pediatric Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2019 | Pubmed ID: 31303380 Overexpression of MiRNA-25-3p Inhibits Notch1 Signaling and TGF-β-induced Collagen Expression in Hepatic Stellate Cells Scientific Reports. Jun, 2019 | Pubmed ID: 31189969 Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Nov, 2019 | Pubmed ID: 30880274 Serum MicroRNAs As Biomarkers in Hepatitis C: Preliminary Evidence of a MicroRNA Panel for the Diagnosis of Hepatocellular Carcinoma International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30781550 Live Imaging of Collagen Deposition During Experimental Hepatic Schistosomiasis and Recovery: a View on a Dynamic Process Laboratory Investigation; a Journal of Technical Methods and Pathology. 02, 2019 | Pubmed ID: 30401957 Cellular Plasticity in Liver Regeneration: Spotlight on Cholangiocytes Hepatology (Baltimore, Md.). May, 2019 | Pubmed ID: 30382597 Detection of HFE Haemochromatosis in the Clinic and Community Using Standard Erythrocyte Tests Blood Cells, Molecules & Diseases. 02, 2019 | Pubmed ID: 30340937 Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE P.C282Y Homozygotes Annals of Hepatology. Aug, 2018 | Pubmed ID: 30145563 MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis Hepatology (Baltimore, Md.). 12, 2018 | Pubmed ID: 30014495 Phenotypic Analysis of Hemochromatosis Subtypes Reveals Variations in Severity of Iron Overload and Clinical Disease Blood. 07, 2018 | Pubmed ID: 29743178 Self-assembling Asymmetric Peptide-dendrimer Micelles - a Platform for Effective and Versatile in Vitro Nucleic Acid Delivery Scientific Reports. 03, 2018 | Pubmed ID: 29556057 Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells Trends in Parasitology. 06, 2018 | Pubmed ID: 29526403 Vitamin A Status in Human Fetuses with Congenital Diaphragmatic Hernia: (Author Reply to Comment by Rocke AW and Clugston RD) Early Human Development. 01, 2018 | Pubmed ID: 29239745 Lung and Liver Growth and Retinoic Acid Status in Human Fetuses with Congenital Diaphragmatic Hernia Early Human Development. 01, 2018 | Pubmed ID: 29096166 Reduction of Body Iron in HFE-related Haemochromatosis and Moderate Iron Overload (Mi-Iron): a Multicentre, Participant-blinded, Randomised Controlled Trial The Lancet. Haematology. Dec, 2017 | Pubmed ID: 29195602 Extracellular Vesicles in the Adaptive Process of Prostate Cancer During Inhibition of Androgen Receptor Signaling by Enzalutamide Proteomics. Dec, 2017 | Pubmed ID: 29105980 Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease The American Journal of Pathology. Sep, 2017 | Pubmed ID: 28935574 Extracellular Vesicles for Personalized Therapy Decision Support in Advanced Metastatic Cancers and Its Potential Impact for Prostate Cancer The Prostate. Oct, 2017 | Pubmed ID: 28856701 Serum Ferritin Concentration Predicts Hepatic Fibrosis Better Than Hepatic Iron Concentration in Human HFE-Haemochromatosis Liver International : Official Journal of the International Association for the Study of the Liver. Sep, 2017 | Pubmed ID: 28231420 Reply Hepatology (Baltimore, Md.). Mar, 2017 | Pubmed ID: 28010035 GNPAT P.D519G is Independently Associated with Markedly Increased Iron Stores in HFE P.C282Y Homozygotes Blood Cells, Molecules & Diseases. Mar, 2017 | Pubmed ID: 27936396 Diagnosing Schistosomiasis-induced Liver Morbidity: Implications for Global Control International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Jan, 2017 | Pubmed ID: 27816660 Filling the Gap on Caveolin-1 in Liver Carcinogenesis Trends in Cancer. Dec, 2016 | Pubmed ID: 28741517 Function and Regulation of MicroRNAs and Their Potential As Biomarkers in Paediatric Liver Disease International Journal of Molecular Sciences. Oct, 2016 | Pubmed ID: 27801781 Caveolin-1 Function in Liver Physiology and Disease Trends in Molecular Medicine. Oct, 2016 | Pubmed ID: 27633517 Transient Liver Elastography in Unsedated Control Children: Impact of Age and Intercurrent Illness Journal of Paediatrics and Child Health. Jun, 2016 | Pubmed ID: 27203205 Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury The American Journal of Pathology. Jul, 2016 | Pubmed ID: 27181403 Mechanism of Pancreatic and Liver Malformations in Human Fetuses with Short-rib Polydactyly Syndrome Birth Defects Research. Part A, Clinical and Molecular Teratology. Jul, 2016 | Pubmed ID: 26970085 Value of the 8-oxodG/dG Ratio in Chronic Liver Inflammation of Patients with Hepatocellular Carcinoma Redox Biology. Aug, 2016 | Pubmed ID: 26890046 Reply Hepatology (Baltimore, Md.). Jun, 2016 | Pubmed ID: 26845080 Characterising Granuloma Regression and Liver Recovery in a Murine Model of Schistosomiasis Japonica International Journal for Parasitology. Apr, 2016 | Pubmed ID: 26812024 The Role of Liver Progenitor Cells During Liver Regeneration, Fibrogenesis, and Carcinogenesis American Journal of Physiology. Gastrointestinal and Liver Physiology. Feb, 2016 | Pubmed ID: 26608186 Reply Hepatology (Baltimore, Md.). Jun, 2016 | Pubmed ID: 26417986 Should HFE P.C282Y Homozygotes with Moderately Elevated Serum Ferritin Be Treated? A Randomised Controlled Trial Comparing Iron Reduction with Sham Treatment (Mi-iron) BMJ Open. Aug, 2015 | Pubmed ID: 26270952 The Development of Hepatic Stellate Cells in Normal and Abnormal Human Fetuses - an Immunohistochemical Study Physiological Reports. Aug, 2015 | Pubmed ID: 26265759 Aspartate Aminotransferase to Platelet Ratio and Fibrosis-4 As Biomarkers in Biopsy-validated Pediatric Cystic Fibrosis Liver Disease Hepatology (Baltimore, Md.). Nov, 2015 | Pubmed ID: 26223427 Transcriptional Profiling of Chronic Clinical Hepatic Schistosomiasis Japonica Indicates Reduced Metabolism and Immune Responses Parasitology. Oct, 2015 | Pubmed ID: 26216487 An Ex Vivo Model for Studying Hepatic Schistosomiasis and the Effect of Released Protein from Dying Eggs PLoS Neglected Tropical Diseases. May, 2015 | Pubmed ID: 25965781 Type 2 Diabetes Mellitus: Limitations of Conventional Therapies and Intervention with Nucleic Acid-based Therapeutics Chemical Reviews. Jun, 2015 | Pubmed ID: 25918949 Reply: To PMID 25605615 Hepatology (Baltimore, Md.). Dec, 2015 | Pubmed ID: 25914125 Reduced Mortality Due to Phlebotomy in Moderately Iron-loaded HFE Haemochromatosis? The Need for Clinical Trials Journal of Hepatology. Jul, 2015 | Pubmed ID: 25839407 Circulating MicroRNAs As Noninvasive Diagnostic Biomarkers of Liver Disease in Children with Cystic Fibrosis Journal of Pediatric Gastroenterology and Nutrition. Feb, 2015 | Pubmed ID: 25625579 Exome Sequencing in HFE C282Y Homozygous Men with Extreme Phenotypes Identifies a GNPAT Variant Associated with Severe Iron Overload Hepatology (Baltimore, Md.). Aug, 2015 | Pubmed ID: 25605615 TWEAK and LTβ Signaling During Chronic Liver Disease Frontiers in Immunology. 2014 | Pubmed ID: 24592262 Ductular Reaction in Hereditary Hemochromatosis: the Link Between Hepatocyte Senescence and Fibrosis Progression Hepatology (Baltimore, Md.). Mar, 2014 | Pubmed ID: 24037895 Transforming Growth Factor-β and Toll-like Receptor-4 Polymorphisms Are Not Associated with Fibrosis in Haemochromatosis World Journal of Gastroenterology. Dec, 2013 | Pubmed ID: 24409064 Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology Michael A. Pearen*1, Hong Kiat Lim*1, Francis D. Gratte2,3, Manuel A. Fernandez-Rojo1,4,5, Sujeevi K. Nawaratna6, Geoffrey N. Gobert7, John K. Olynyk8,9, Janina E. E. Tirnitz-Parker2,10, Grant A. Ramm1,4 1Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, 2School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, 3School of Veterinary and Life Sciences, Murdoch University, 4School of Medicine, The University of Queensland, 5Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, 6School of Medicine, Griffith University, 7School of Biological Sciences, Queen's University Belfast, 8Department of Gastroenterology & Hepatology, Fiona Stanley and Fremantle Hospital Group, 9School of Medical and Health Sciences, Edith Cowan University, 10Centre for Cell Therapy and Regenerative Medicine, School of Biomedical Sciences, University of Western Australia JoVE 60992 Medicina
Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology Michael A. Pearen*1, Hong Kiat Lim*1, Francis D. Gratte2,3, Manuel A. Fernandez-Rojo1,4,5, Sujeevi K. Nawaratna6, Geoffrey N. Gobert7, John K. Olynyk8,9, Janina E. E. Tirnitz-Parker2,10, Grant A. Ramm1,4 1Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, 2School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, 3School of Veterinary and Life Sciences, Murdoch University, 4School of Medicine, The University of Queensland, 5Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, 6School of Medicine, Griffith University, 7School of Biological Sciences, Queen's University Belfast, 8Department of Gastroenterology & Hepatology, Fiona Stanley and Fremantle Hospital Group, 9School of Medical and Health Sciences, Edith Cowan University, 10Centre for Cell Therapy and Regenerative Medicine, School of Biomedical Sciences, University of Western Australia JoVE 60992 Medicina