Henri G.D. Leuvenink Surgical Research Laboratory, Department of Surgery University of Groningen, University Medical Center Groningen Biography Publications Institution JoVE Articles Henri G.D. Leuvenink has not added a biography. If you are Henri G.D. Leuvenink and would like to personalize this page please email our Author Liaison for assistance. Publications Novel Organ Preservation Methods: Not Only Cool but Supercool! Transplantation. Apr, 2015 | Pubmed ID: 25827321 Hydrogen Sulfide in Renal Physiology, Disease and Transplantation--the Smell of Renal Protection Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Apr, 2015 | Pubmed ID: 25656225 Hydrogen Sulfide: Physiological Properties and Therapeutic Potential in Ischaemia British Journal of Pharmacology. Mar, 2015 | Pubmed ID: 25091411 Sodium Thiosulfate Attenuates Angiotensin II-induced Hypertension, Proteinuria and Renal Damage Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2014 | Pubmed ID: 25459997 Hypoxia and Complement-and-Coagulation Pathways in the Deceased Organ Donor As the Major Target for Intervention to Improve Renal Allograft Outcome Transplantation. Nov, 2014 | Pubmed ID: 25427168 Criteria for Viability Assessment of Discarded Human Donor Livers During Ex Vivo Normothermic Machine Perfusion PloS One. 2014 | Pubmed ID: 25369327 Prednisolone Has a Positive Effect on the Kidney but Not on the Liver of Brain Dead Rats: a Potencial Role in Complement Activation Journal of Translational Medicine. 2014 | Pubmed ID: 24884924 Reply: To PMID 24355874 Journal of the American College of Surgeons. May, 2014 | Pubmed ID: 24745572 α-Melanocyte Stimulating Hormone Treatment in Pigs Does Not Improve Early Graft Function in Kidney Transplants from Brain Dead Donors PloS One. 2014 | Pubmed ID: 24728087 Histopathologic and Molecular Evaluation of the Organ Procurement and Transplantation Network Selection Criteria for Intestinal Graft Donation The Journal of Surgical Research. Jun, 2014 | Pubmed ID: 24655665 Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated After Circulatory Death PloS One. 2014 | Pubmed ID: 24551114 Early Angiopoietin-2 Levels After Onset Predict the Advent of Severe Pancreatitis, Multiple Organ Failure, and Infectious Complications in Patients with Acute Pancreatitis Journal of the American College of Surgeons. Jan, 2014 | Pubmed ID: 24355874 Erythropoietin-mediated Protection in Kidney Transplantation: Nonerythropoietic EPO Derivatives Improve Function Without Increasing Risk of Cardiovascular Events Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2014 | Pubmed ID: 23964738 Renoprotective Capacities of Non-erythropoietic EPO Derivative, ARA290, Following Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 24225194 Gaseous Hydrogen Sulfide Protects Against Myocardial Ischemia-reperfusion Injury in Mice Partially Independent from Hypometabolism PloS One. 2013 | Pubmed ID: 23675473 A Human Model of Intra-abdominal Hypertension: Even Slightly Elevated Pressures Lead to Increased Acute Systemic Inflammation and Signs of Acute Kidney Injury Critical Care (London, England). 2013 | Pubmed ID: 23566574 Nonesterified Fatty Acids and Development of Graft Failure in Renal Transplant Recipients Transplantation. Jun, 2013 | Pubmed ID: 23524974 Cystathionine γ-lyase Protects Against Renal Ischemia/reperfusion by Modulating Oxidative Stress Journal of the American Society of Nephrology : JASN. Apr, 2013 | Pubmed ID: 23449534 Are Brain and Heart Tissue Prone to the Development of Thiamine Deficiency? Alcohol (Fayetteville, N.Y.). May, 2013 | Pubmed ID: 23357554 Brain Death Induces Renal Expression of Heme Oxygenase-1 and Heat Shock Protein 70 Journal of Translational Medicine. 2013 | Pubmed ID: 23356498 SLC22A2 is Associated with Tubular Creatinine Secretion and Bias of Estimated GFR in Renal Transplantation Physiological Genomics. Mar, 2013 | Pubmed ID: 23341218 ARA290, a Non-erythropoietic EPO Derivative, Attenuates Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 23302512 UMOD As a Susceptibility Gene for End-stage Renal Disease BMC Medical Genetics. 2012 | Pubmed ID: 22947327 Beneficial Effects of Gaseous Hydrogen Sulfide in Hepatic Ischemia/reperfusion Injury Transplant International : Official Journal of the European Society for Organ Transplantation. Aug, 2012 | Pubmed ID: 22716165 CUBN As a Novel Locus for End-stage Renal Disease: Insights from Renal Transplantation PloS One. 2012 | Pubmed ID: 22574174 L'effetto Della Ridotta Ricircolo Prima Conservazione Freddo Su Lesioni Post-trapianto Di Reni Del Donatore Ischemically Danneggiato Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2012 | Pubmed ID: 22077364 Perfusione Macchina Versus Frigorifere Per La Conservazione Dei Reni Da Donatori Criteri Ampliato Dopo La Morte Cerebrale Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2011 | Pubmed ID: 21332580 Conservazione Del Piccolo Intestino Per Trapianto Intestinale: Una Revisione Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2011 | Pubmed ID: 21083772 Quanto è Importante La Durata Del Periodo Di Morte Cerebrale Per L'esito Nel Trapianto Di Rene? Transplant International : Official Journal of the European Society for Organ Transplantation. Jan, 2011 | Pubmed ID: 20819191 Perfusione Macchina Versus Frigorifere Per La Conservazione Dei Reni Ha Donato Dopo Morte Cardiaca: Un Trial Multicentrico, Randomizzato, Controllato Annals of Surgery. Nov, 2010 | Pubmed ID: 21037431 Il Valore Della Macchina Perfusione Perfusato Biomarkers Per Predire L'esito Del Trapianto Di Rene Transplantation. Nov, 2010 | Pubmed ID: 20861807 Lesioni Ridotta Ischemia-riossigenazione Nell'intestino Del Ratto Dopo Conservazione Del Lume Con Una Soluzione Su Misura Transplantation. Sep, 2010 | Pubmed ID: 20689496 Eparina Binding Epidermal Growth Factor in Lesioni Renali Ischemia/reperfusion The Journal of Pathology. Jun, 2010 | Pubmed ID: 20225242 Pretrattamento Dei Donatori Con Carbamylated Eritropoietina in Un Modello Di Morte Cerebrale Riduce L'infiammazione Più Efficacemente Di Eritropoietina Preservando La Funzione Renale Critical Care Medicine. Apr, 2010 | Pubmed ID: 20124889 Severe Thiamine Deficiency Complicated by Weight Loss Protects Against Renal Ischaemia-reperfusion Injury in Rats NDT Plus. Apr, 2009 | Pubmed ID: 25949326 L'influenza Di Allocazione Di Età E Vecchio Per Vecchio Donatore Deceduto Sull'esito Del Trapianto Di Rene Transplantation. Aug, 2009 | Pubmed ID: 19696638 Aumento Della Permeabilità Intestinale in Ratti Morti Cerebrali Defunto Transplantation. Aug, 2009 | Pubmed ID: 19667953 Hydrogen Sulfide-induced Hypometabolism Prevents Renal Ischemia/reperfusion Injury Journal of the American Society of Nephrology : JASN. Sep, 2009 | Pubmed ID: 19628669 The Goddess of the Waters Kidney International. Apr, 2009 | Pubmed ID: 19337215 Perfusione Macchina O Cold Storage Nel Trapianto Di Rene Del Defunto-donatore The New England Journal of Medicine. Jan, 2009 | Pubmed ID: 19118301 Deterioramento Della Funzione Delle Cellule Endoteliali E Lisci Del Muscolo in Reni DCD Dopo Archiviazione Statica Cold IGL-1, O UW The Journal of Surgical Research. Apr, 2009 | Pubmed ID: 18701116 Morte Cerebrale Induce Infiammazione Nell'intestino Dei Donatori Transplantation. Jul, 2008 | Pubmed ID: 18622292 Primi Eventi in Donazione Di Rene: Progressione Di Attivazione Endoteliale, Stress Ossidativo E Tubolari Lesioni Dopo La Morte Cerebrale American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. May, 2008 | Pubmed ID: 18318776 Frigorifere Statiche Conservazione Dei Reni Ischemically Danneggiati. Un Confronto Tra Soluzione UW E IGL-1 Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2008 | Pubmed ID: 18225993 Migliorata Funzione Di Trapianto Renale Dopo Conservazione Utilizzando Un Dispositivo Di Perfusione Romanzo Macchina Ipotermia Annals of Surgery. Dec, 2007 | Pubmed ID: 18043100 Il Modello Di Esordio Graduale Morte Cerebrale: Un Modello Rilevante Per Studiare La Donazione Di Organi E Le Sue Conseguenze Sul Risultato Dopo Il Trapianto Laboratory Animals. Jul, 2007 | Pubmed ID: 17640464 Prospettive Nella Conservazione Di Organo Transplantation. May, 2007 | Pubmed ID: 17519776 Tissue Thiamine Deficiency As Potential Cause of Delayed Graft Function After Kidney Transplantation: Thiamine Supplementation of Kidney Donors May Improve Transplantation Outcome Medical Hypotheses. 2007 | Pubmed ID: 17379423 Determinazione Di Una Pressione Adeguata Perfusione Per Perfusione Ipotermico Macchina Continuo Doppio Vaso Del Fegato Di Ratto Transplant International : Official Journal of the European Society for Organ Transplantation. Apr, 2007 | Pubmed ID: 17326775 La Donazione Di Organi Non-cuore Battere: Panoramica E Prospettive Future Transplant International : Official Journal of the European Society for Organ Transplantation. Jul, 2007 | Pubmed ID: 17263786 Spatiotemporal Espressione Della Eme Ossigenasi-1 Rilevato Da Bioluminescenza in Vivo Dopo Ischemia Epatica in Topi HO-1/Luc Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2006 | Pubmed ID: 17058249 Acuta Isovolemic Hemodilution Innesca Proinflammatory E Procoagulatory Attivazione Endoteliale in Organi Vitali: Ruolo Di Aggregazione Degli Eritrociti Microcirculation (New York, N.Y. : 1994). Jul-Aug, 2006 | Pubmed ID: 16815825 Citoprotettivo Dosi Di Eritropoietina O Carbamylated Eritropoietina Hanno Nettamente Diverso Procoagulante E Attività Vasoattivo Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006 | Pubmed ID: 16585502 Hepatic Expression of ABC Transporters G5 and G8 Does Not Correlate with Biliary Cholesterol Secretion in Liver Transplant Patients Hepatology (Baltimore, Md.). Nov, 2005 | Pubmed ID: 16250035 Ossigenazione Durante La Conservazione Ipotermico Di Fegato Di Ratto: Uno Studio in Vitro Fetta Per Dimostrare Gli Effetti Benefici O Tossici Di Ossigenazione Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2005 | Pubmed ID: 16237692 Expression of Heme Oxygenase-1 in Human Livers Before Transplantation Correlates with Graft Injury and Function After Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2005 | Pubmed ID: 15996234 Rapid Increase of Bile Salt Secretion is Associated with Bile Duct Injury After Human Liver Transplantation Journal of Hepatology. Dec, 2004 | Pubmed ID: 15582136 Distinti Transcriptional Cambiamenti Nei Reni Del Donatore Dopo Induzione Di Morte Cerebrale in Ratti: Intuizioni Nei Processi Di Morte Cerebrale American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2004 | Pubmed ID: 15575899 Effetto Della Morte Cerebrale Sull'attivazione Del Gene Expression E Tessuto in Reni Del Donatore Umano Transplantation. Oct, 2004 | Pubmed ID: 15480162 Lavaggio Iniziale Sangue Durante Gli Appalti Organo Determina Danno Epatico E Funzione Dopo Conservazione E Riperfusione American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2004 | Pubmed ID: 15476484 Effetto Della University of Wisconsin Organo-conservazione Soluzione Su Haemorheology Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2004 | Pubmed ID: 15146313 Conservazione Macchina Ipotermia Nel Trapianto Di Fegato Rivisitato: Concetti E Criteri Nel Nuovo Millennio Annals of Biomedical Engineering. Apr, 2004 | Pubmed ID: 15117035 Effetto Della Morte Cerebrale E Donazione Di Rene-cuore-battendo Sulla Funzione Renale E Lesioni: Una Valutazione Nel Rene Di Ratto Perfusi Isolati Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. Dec, 2003 | Pubmed ID: 15859914 Macrophage Overgrowth Affects Neighboring Nonovergrown Encapsulated Islets The Journal of Surgical Research. Dec, 2003 | Pubmed ID: 14697289 Effective Removal of Alginate-poly-L-lysine Microcapsules from Pancreatic Islets by Use of Trypsin-EDTA Journal of Biomedical Materials Research. Part A. Nov, 2003 | Pubmed ID: 14566813 Rapporto Tra Durata Della Morte Cerebrale Ed Emodinamica (in) Stabilità Sulla Disfunzione Progressiva E Maggiore Attivazione Immunologica Dei Reni Del Donatore Kidney International. Nov, 2003 | Pubmed ID: 14531823 Hyperaggregating Effetto Di Componenti Di Amido Idrossietilico E University of Wisconsin Soluzione Su Eritrociti Umani: Un Rischio Di Perfusione Alterata Innesto Negli Appalti Organo? Transplantation. Jul, 2003 | Pubmed ID: 12865783 Ex Situ normotermica macchina di perfusione di Vivi donatori Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicina
Ex Situ normotermica macchina di perfusione di Vivi donatori Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicina