Huili Hu Key Laboratory of Experimental Teratology, Ministry of Education, Institute of Molecular Medicine and Genetics, School of Basic Medical Sciences, Stem Cell and Regenerative Medicine Research Center, Cheeloo College of Medicine Shandong University Biography Publications Institution JoVE Articles Huili Hu has not added a biography. If you are Huili Hu and would like to personalize this page please email our Author Liaison for assistance. Publications Discovery of a INSIG Binding Compound That Ameliorates Nonalcoholic Steatohepatitis by Inhibiting SREBP-mediated Lipogenesis Hepatology (Baltimore, Md.). Jan, 2022 | Pubmed ID: 35102596 A Combined Model of Human IPSC-Derived Liver Organoids and Hepatocytes Reveals Ferroptosis in DGUOK Mutant MtDNA Depletion Syndrome Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 05, 2021 | Pubmed ID: 34026460 CUL4B Facilitates HBV Replication by Promoting HBx Stabilization Cancer Biology & Medicine. May, 2021 | Pubmed ID: 33969670 CUL4B Promotes Temozolomide Resistance in Gliomas by Epigenetically Repressing Transcription Frontiers in Oncology. 2021 | Pubmed ID: 33869025 CUL4B Contributes to Cancer Stemness by Repressing Tumor Suppressor MiR34a in Colorectal Cancer Oncogenesis. Feb, 2020 | Pubmed ID: 32054830 Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids Cell Stem Cell. Jun, 2019 | Pubmed ID: 31130514 Cul4a Promotes Zebrafish Primitive Erythropoiesis Via Upregulating Scl and Gata1 Expression Cell Death & Disease. 05, 2019 | Pubmed ID: 31101894 Long-Term Expansion of Functional Mouse and Human Hepatocytes As 3D Organoids Cell. 11, 2018 | Pubmed ID: 30500538 A Cullin 4B-RING E3 Ligase Complex Fine-tunes Pancreatic δ Cell Paracrine Interactions The Journal of Clinical Investigation. Jun, 2017 | Pubmed ID: 28604389 Dysregulation of the MiR-194-CUL4B Negative Feedback Loop Drives Tumorigenesis in Non-small-cell Lung Carcinoma Molecular Oncology. 03, 2017 | Pubmed ID: 28164432 The CUL4B/AKT/β-Catenin Axis Restricts the Accumulation of Myeloid-Derived Suppressor Cells to Prohibit the Establishment of a Tumor-Permissive Microenvironment Cancer Research. Dec, 2015 | Pubmed ID: 26450912 MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C Scientific Reports. Jul, 2015 | Pubmed ID: 26184978 Lack of CUL4B Leads to Increased Abundance of GFAP-positive Cells That is Mediated by PTGDS in Mouse Brain Human Molecular Genetics. Aug, 2015 | Pubmed ID: 26025376 CUL4B Activates Wnt/β-catenin Signalling in Hepatocellular Carcinoma by Repressing Wnt Antagonists The Journal of Pathology. Apr, 2015 | Pubmed ID: 25430888 Zebrafish Cul4a, but Not Cul4b, Modulates Cardiac and Forelimb Development by Upregulating Tbx5a Expression Human Molecular Genetics. Feb, 2015 | Pubmed ID: 25274780 CRL4B Interacts with and Coordinates the SIN3A-HDAC Complex to Repress CDKN1A and Drive Cell Cycle Progression Journal of Cell Science. Nov, 2014 | Pubmed ID: 25189618 Chemokine Receptor CXCR2 is Transactivated by P53 and Induces P38-mediated Cellular Senescence in Response to DNA Damage Aging Cell. Dec, 2013 | Pubmed ID: 23869868 CUL4B Promotes Replication Licensing by Up-regulating the CDK2-CDC6 Cascade The Journal of Cell Biology. Mar, 2013 | Pubmed ID: 23479742 CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis Cancer Cell. Dec, 2012 | Pubmed ID: 23238014 A Missense Mutation in SLC33A1, Which Encodes the Acetyl-CoA Transporter, Causes Autosomal-dominant Spastic Paraplegia (SPG42) American Journal of Human Genetics. Dec, 2008 | Pubmed ID: 19061983 Establecimiento y manipulación genética de organoides hepatocitos murinos Jiabei Lian*1,2, Xinyuan Meng*1,3, Xiaohui Zhang1,2, Huili Hu1,2 1Key Laboratory of Experimental Teratology, Ministry of Education, Institute of Molecular Medicine and Genetics, School of Basic Medical Sciences, Stem Cell and Regenerative Medicine Research Center, Cheeloo College of Medicine, Shandong University, 2The Research Center of Stem Cell and Regenerative Medicine, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Shandong University JoVE 62438 Biologia
Establecimiento y manipulación genética de organoides hepatocitos murinos Jiabei Lian*1,2, Xinyuan Meng*1,3, Xiaohui Zhang1,2, Huili Hu1,2 1Key Laboratory of Experimental Teratology, Ministry of Education, Institute of Molecular Medicine and Genetics, School of Basic Medical Sciences, Stem Cell and Regenerative Medicine Research Center, Cheeloo College of Medicine, Shandong University, 2The Research Center of Stem Cell and Regenerative Medicine, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Shandong University JoVE 62438 Biologia