Ian Sigal Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center University of Pittsburgh School of Medicine Biography Publications Institution JoVE Articles Ian Sigal has not added a biography. If you are Ian Sigal and would like to personalize this page please email our Author Liaison for assistance. Publications Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images Investigative Ophthalmology & Visual Science. Jun, 2015 | Pubmed ID: 26066749 In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT Investigative Ophthalmology & Visual Science. Jun, 2015 | Pubmed ID: 26066747 Translating Ocular Biomechanics into Clinical Practice: Current State and Future Prospects Current Eye Research. Jan, 2015 | Pubmed ID: 24832392 Parameters for Lithium Treatment Are Critical in Its Enhancement of Fracture-healing in Rodents The Journal of Bone and Joint Surgery. American Volume. Dec, 2014 | Pubmed ID: 25471914 In Vivo Three-dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Oct, 2014 | Pubmed ID: 25228539 Magic Angle-enhanced MRI of Fibrous Microstructures in Sclera and Cornea with and Without Intraocular Pressure Loading Investigative Ophthalmology & Visual Science. Sep, 2014 | Pubmed ID: 25103267 Recent Advances in OCT Imaging of the Lamina Cribrosa The British Journal of Ophthalmology. Jul, 2014 | Pubmed ID: 24934221 Repeatability of in Vivo 3D Lamina Cribrosa Microarchitecture Using Adaptive Optics Spectral Domain Optical Coherence Tomography Biomedical Optics Express. Apr, 2014 | Pubmed ID: 24761293 Reproducibility of In-vivo OCT Measured Three-dimensional Human Lamina Cribrosa Microarchitecture PloS One. 2014 | Pubmed ID: 24747957 Gold Nanorods As a Contrast Agent for Doppler Optical Coherence Tomography PloS One. 2014 | Pubmed ID: 24595044 Characterisation of Schlemm's Canal Cross-sectional Area The British Journal of Ophthalmology. Jul, 2014 | Pubmed ID: 24590558 IOP Elevation Reduces Schlemm's Canal Cross-sectional Area Investigative Ophthalmology & Visual Science. Mar, 2014 | Pubmed ID: 24526436 Eye-specific IOP-induced Displacements and Deformations of Human Lamina Cribrosa Investigative Ophthalmology & Visual Science. Jan, 2014 | Pubmed ID: 24334450 In Vivo Lamina Cribrosa Micro-architecture in Healthy and Glaucomatous Eyes As Assessed by Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24302585 Automated Lamina Cribrosa Microstructural Segmentation in Optical Coherence Tomography Scans of Healthy and Glaucomatous Eyes Biomedical Optics Express. 2013 | Pubmed ID: 24298418 Signal Normalization Reduces Systematic Measurement Differences Between Spectral-domain Optical Coherence Tomography Devices Investigative Ophthalmology & Visual Science. Nov, 2013 | Pubmed ID: 24114534 Individual A-scan Signal Normalization Between Two Spectral Domain Optical Coherence Tomography Devices Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23611992 High Dynamic Range Imaging Concept-based Signal Enhancement Method Reduced the Optical Coherence Tomography Measurement Variability Investigative Ophthalmology & Visual Science. Jan, 2013 | Pubmed ID: 23299477 Human Lamina Cribrosa Insertion and Age Investigative Ophthalmology & Visual Science. Oct, 2012 | Pubmed ID: 22956611 Visualization of the Conventional Outflow Pathway in the Living Human Eye Ophthalmology. Aug, 2012 | Pubmed ID: 22683063 A Few Good Responses: Which Mechanical Effects of IOP on the ONH to Study? Investigative Ophthalmology & Visual Science. 2012 | Pubmed ID: 22570343 Morphometric Analysis of Aqueous Humor Outflow Structures with Spectral-domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. Aug, 2012 | Pubmed ID: 22499987 The Optic Nerve Head As a Robust Biomechanical System Investigative Ophthalmology & Visual Science. May, 2012 | Pubmed ID: 22427598 Lamina Cribrosa Thickening in Early Glaucoma Predicted by a Microstructure Motivated Growth and Remodeling Approach Mechanics of Materials : an International Journal. Jan, 2012 | Pubmed ID: 22389541 Effect of Acute Intraocular Pressure Elevation on the Monkey Optic Nerve Head As Detected by Spectral Domain Optical Coherence Tomography Investigative Ophthalmology & Visual Science. 2011 | Pubmed ID: 22058335 IOP-induced Lamina Cribrosa Deformation and Scleral Canal Expansion: Independent or Related? Investigative Ophthalmology & Visual Science. Nov, 2011 | Pubmed ID: 21989723 Posterior (outward) Migration of the Lamina Cribrosa and Early Cupping in Monkey Experimental Glaucoma Investigative Ophthalmology & Visual Science. 2011 | Pubmed ID: 21715355 An Applet to Estimate the IOP-induced Stress and Strain Within the Optic Nerve Head Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21527378 3D Visualization of Aqueous Humor Outflow Structures In-situ in Humans Experimental Eye Research. Sep, 2011 | Pubmed ID: 21514296 Longitudinal Change Detected by Spectral Domain Optical Coherence Tomography in the Optic Nerve Head and Peripapillary Retina in Experimental Glaucoma Investigative Ophthalmology & Visual Science. Mar, 2011 | Pubmed ID: 21217108 Finite Element Modeling of the Human Sclera: Influence on Optic Nerve Head Biomechanics and Connections with Glaucoma Experimental Eye Research. Jul, 2011 | Pubmed ID: 20883693 IOP-induced Lamina Cribrosa Displacement and Scleral Canal Expansion: an Analysis of Factor Interactions Using Parameterized Eye-specific Models Investigative Ophthalmology & Visual Science. Mar, 2011 | Pubmed ID: 20881292 Glaucomatous Cupping of the Lamina Cribrosa: a Review of the Evidence for Active Progressive Remodeling As a Mechanism Experimental Eye Research. Aug, 2011 | Pubmed ID: 20708001 Deformation of the Early Glaucomatous Monkey Optic Nerve Head Connective Tissue After Acute IOP Elevation in 3-D Histomorphometric Reconstructions Investigative Ophthalmology & Visual Science. Jan, 2011 | Pubmed ID: 20702834 A Geometric Morphometric Assessment of the Optic Cup in Glaucoma Experimental Eye Research. Sep, 2010 | Pubmed ID: 20599965 Changes in the Biomechanical Response of the Optic Nerve Head in Early Experimental Glaucoma Investigative Ophthalmology & Visual Science. Nov, 2010 | Pubmed ID: 20538991 Dimensions of the Human Sclera: Thickness Measurement and Regional Changes with Axial Length Experimental Eye Research. Feb, 2010 | Pubmed ID: 19900442 Morphing Methods to Parameterize Specimen-specific Finite Element Model Geometries Journal of Biomechanics. Jan, 2010 | Pubmed ID: 19878950 Mesh Morphing and Response Surface Analysis: Quantifying Sensitivity of Vertebral Mechanical Behavior Annals of Biomedical Engineering. Jan, 2010 | Pubmed ID: 19859809 3D Morphometry of the Human Optic Nerve Head Experimental Eye Research. Jan, 2010 | Pubmed ID: 19772858 Correlation Between Local Stress and Strain and Lamina Cribrosa Connective Tissue Volume Fraction in Normal Monkey Eyes Investigative Ophthalmology & Visual Science. Jan, 2010 | Pubmed ID: 19696175 Deformation of the Normal Monkey Optic Nerve Head Connective Tissue After Acute IOP Elevation Within 3-D Histomorphometric Reconstructions Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19628739 Biomechanics of the Optic Nerve Head Experimental Eye Research. Apr, 2009 | Pubmed ID: 19217902 Interactions Between Geometry and Mechanical Properties on the Optic Nerve Head Investigative Ophthalmology & Visual Science. Jun, 2009 | Pubmed ID: 19168906 Modeling Individual-specific Human Optic Nerve Head Biomechanics. Part I: IOP-induced Deformations and Influence of Geometry Biomechanics and Modeling in Mechanobiology. Apr, 2009 | Pubmed ID: 18309526 Modeling Individual-specific Human Optic Nerve Head Biomechanics. Part II: Influence of Material Properties Biomechanics and Modeling in Mechanobiology. Apr, 2009 | Pubmed ID: 18301933 Mesh-morphing Algorithms for Specimen-specific Finite Element Modeling Journal of Biomechanics. 2008 | Pubmed ID: 18397789 Predicted Extension, Compression and Shearing of Optic Nerve Head Tissues Experimental Eye Research. Sep, 2007 | Pubmed ID: 17624325 Factors Influencing Optic Nerve Head Biomechanics Investigative Ophthalmology & Visual Science. Nov, 2005 | Pubmed ID: 16249498 Reconstruction of Human Optic Nerve Heads for Finite Element Modeling Technology and Health Care : Official Journal of the European Society for Engineering and Medicine. 2005 | Pubmed ID: 16055979 Finite Element Modeling of Optic Nerve Head Biomechanics Investigative Ophthalmology & Visual Science. Dec, 2004 | Pubmed ID: 15557446 살아있는 인간의 눈의 압력 상승에 섬유주 응답 Larry Kagemann1,2, Bo Wang2, Gadi Wollstein1, Hiroshi Ishikawa1,2, Brandon Mentley1, Ian Sigal1,2,3, Richard A Bilonick1,4, Joel S Schuman1,2,3 1Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, 2Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 3The McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 4Deptartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh JoVE 52611 Medicina
살아있는 인간의 눈의 압력 상승에 섬유주 응답 Larry Kagemann1,2, Bo Wang2, Gadi Wollstein1, Hiroshi Ishikawa1,2, Brandon Mentley1, Ian Sigal1,2,3, Richard A Bilonick1,4, Joel S Schuman1,2,3 1Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, 2Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, 3The McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine, 4Deptartment of Biostatistics, Graduate School of Public Health, University of Pittsburgh JoVE 52611 Medicina